Gene News and Research

Latest Gene News and Research

Gene therapy to the inner retina prevents blindness in mouse model of CLN3 Batten disease

Gene therapy to the inner retina prevented blindness in a mouse model of the neuro-degenerative disorder CLN3 Batten disease.

10 Aug 2020

NIH awards $1.2 million grant to create humanized mice susceptible to COVID-19

The National Institutes of Health has awarded a grant of $1.2 million to the Mouse Biology Program at the University of California, Davis, to create mice that are susceptible to the COVID-19 virus, and to distribute them to researchers.

10 Aug 2020

Dietary interventions to optimize healing of injury-induced inflammation

Injuries induce the initiation of inflammation to control the damage. However, the resolution of the injury-induced inflammation leading to healing is not well characterized.

10 Aug 2020

AI-enhanced precision medicine approach lays groundwork for identification of autism subtype

A novel precision medicine approach enhanced by artificial intelligence (AI) has laid the groundwork for what could be the first biomedical screening and intervention tool for a subtype of autism, reports a new study from Northwestern University, Ben Gurion University, Harvard University and the Massachusetts Institute of Technology.

10 Aug 2020

Quantum cryptographic communications technology can provide safe, secure data transmission in genomic medicine

Toshiba Corporation, Tohoku University Tohoku Medical Megabank Organization and Tohoku University Hospital have demonstrated that quantum cryptographic communications technology can provide genomic medicine with a safe, completely secure data management environment.

10 Aug 2020

Study suggests novel strategy to slow down evolution of antibiotic resistance

The rise of antibiotic resistance in many pathogens has been driven by the spread of a small number of strains, suggesting that some bacteria may be genetically pre-disposed to evolving resistance.

10 Aug 2020

Genetic variant in Japanese population increases risk of interstitial lung disease among RA patients

In many cases, a complex interplay between our genes and the environment governs whether or not we will develop a certain disease. Interestingly though, researchers are discovering that the genetic component of disease predisposition may depend on our ethnic background.

10 Aug 2020

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

As COVID-19 continues to take a heavy toll on human health and life in many parts of the world, there is still no effective antiviral drug or vaccine. This has fueled an intensive search for small molecules and proteins that can inhibit viral entry and replication.

10 Aug 2020

FDA approves first companion diagnostic that uses liquid biopsy and NGS technology

Today, the U.S. Food and Drug Administration approved the first liquid biopsy companion diagnostic that also uses next-generation sequencing (NGS) technology to identify patients with specific types of mutations of the epidermal growth factor receptor (EGFR) gene in a deadly form of metastatic non-small cell lung cancer (NSCLC).

7 Aug 2020

Method provides new insight into brain cells that maintain body's master circadian clock.

UT Southwestern scientists have developed a genetically engineered mouse and imaging system that lets them visualize fluctuations in the circadian clocks of cell types in mice.

7 Aug 2020

New approach improves SCA1 symptoms in animal models

Research has shown that a mutation in the ATAXIN-1 gene leads to accumulation of Ataxin-1 (ATXN1) protein in brain cells and is the root cause of a rare genetic neurodegenerative disease known as spinocerebellar ataxia type 1 (SCA1).

7 Aug 2020

Study shows link between high blood lead levels and aberrant methylation of DNA

Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.

7 Aug 2020

Nanomedicine-based strategy enhances anti-PD1 therapy to eradicate PTEN-negative GBM

A nanomedicine-based strategy for chemo-immunotherapy (CIT) of glioblastoma (GBM), which has the worst prognosis among brain tumors, was successfully developed.

7 Aug 2020

NSD2 enzyme protects against cellular senescence

Researchers from Kumamoto University in Japan have used comprehensive genetic analysis to find that the enzyme NSD2, which is known to regulate the actions of many genes, also works to block cell aging.

7 Aug 2020

USF Health researchers develop new reporter mouse strain for identifying P2X2-expressing cells

Despite frequent news announcing "medical breakthroughs," advancements in biomedical and clinical science typically happen incrementally.

7 Aug 2020

Study reveals the genetic cause of congenital malformation

Study by the University of Bonn reveals that genetic information controls development of the urinary tract, rectum and genitals Spontaneous mutations of a single gene are likely to cause serious developmental disorders of the excretory organs and genitalia.

7 Aug 2020

Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments

A large-scale analysis of the clinical characteristics of Alport syndrome in Japanese patients has revealed that the effectiveness of existing treatment with ACE inhibitors and/or angiotensin receptor blockers (RAS inhibitors) varies depending on the type of mutation in the syndrome's causal gene (COL4A5).

7 Aug 2020

Gene News and Research

Latest Gene News and Research

Gene therapy to the inner retina prevents blindness in mouse model of CLN3 Batten disease

NIH awards $1.2 million grant to create humanized mice susceptible to COVID-19

Dietary interventions to optimize healing of injury-induced inflammation

AI-enhanced precision medicine approach lays groundwork for identification of autism subtype

Quantum cryptographic communications technology can provide safe, secure data transmission in genomic medicine

Study suggests novel strategy to slow down evolution of antibiotic resistance

Genetic variant in Japanese population increases risk of interstitial lung disease among RA patients

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

FDA approves first companion diagnostic that uses liquid biopsy and NGS technology

Method provides new insight into brain cells that maintain body's master circadian clock.

New approach improves SCA1 symptoms in animal models

Study shows link between high blood lead levels and aberrant methylation of DNA

Nanomedicine-based strategy enhances anti-PD1 therapy to eradicate PTEN-negative GBM

NSD2 enzyme protects against cellular senescence

USF Health researchers develop new reporter mouse strain for identifying P2X2-expressing cells

Study reveals the genetic cause of congenital malformation

Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments

Study: Early training of cell development and network improves response

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

Immune system derails during severe course of COVID-19

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging