Gene News and Research

Latest Gene News and Research

Study could help understand the evolution of nervous systems in animals and humans

When it comes to brain cells, one size does not fit all. Neurons come in a wide variety of shapes, sizes, and contain different types of brain chemicals. But how did they get that way?

20 Aug 2020

Study indicates a potential link between Alzheimer's and common brain disorder

Alzheimer's disease is one of the most common causes of dementia, and while most people might know someone who is affected by it, the genetic factors behind the disease are less known.

20 Aug 2020

Researchers identify mechanism that explains lower-quality immune response in COVID-19 patients

The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19.

20 Aug 2020

Adaptions to aging may be impacted by genetic background

How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside.

19 Aug 2020

Genomics study shows multiple and diverse SARS-CoV-2 introductions in the US capital region

A recent study led by the researchers from Johns Hopkins University reveals multiple and diverse introductions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the United States National Capital Region during the initial phase of coronavirus disease 2019 (COVID-19) pandemic. The study is currently available on the medRxiv* preprint server.

19 Aug 2020

New database could speed the development of gene-targeted therapies for breast cancer

All current breast cancer drugs were first tested in cell lines. Each cell line began as cancer in a patient. As such, each cell line is a surrogate for that patient's disease.

19 Aug 2020

New approach to chronic pain treatment could bring relief

Something like a quarter of the world's population suffers from chronic pain at some point in their lives. As opposed to acute pain - for example, the feeling after hitting your finger with a hammer - chronic pain may not even have a clear cause, and it can linger for years or lifetimes.

19 Aug 2020

Study investigates onset of spinocerebellar ataxia associated with loss of motor coordination

A European research alliance tracks the onset of ataxias "Spinocerebellar ataxias" are diseases of the nervous system associated with a loss of motor coordination.

19 Aug 2020

Single-dose adenovirus-vectored vaccine protects mice against SARS-CoV-2

The researchers selected the human adenovirus type 5 on which to base their vaccine because this replication-defective vector had already been used in their Ebola vaccine, with an excellent safety and immunogenicity profile in a phase 1 trial. The current study aimed to produce a vaccine that could offer mucosal vaccination and enhanced protection against this respiratory virus.

19 Aug 2020

Study identifies key gene as future therapeutic target for aggressive endometrial cancer

A new study has identified a key gene in aggressive endometrial cancer, which could lead to a targeted therapeutic strategy to improve survival rates.

19 Aug 2020

Antibody and cellular immunity in severe vs. mild COVID-19

Now, a new study published in the journal Signal Transduction and Targeted Therapy in August 2020 shows that while humoral and T-cell immune responses are more robust in severe infection, the disease activates memory T cells as part of the adaptive immune system in COVID-19 patients irrespective of disease severity.

18 Aug 2020

Study shows how common drug paralyzes the parasites that cause elephantiasis

For years, many scientists and medical professionals likely misunderstood how a commonly prescribed medication for elephantiasis battled the disease, but a new study sets the record straight.

18 Aug 2020

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

ETH Zurich scientists have developed an RNA molecule that can be used in bone marrow cells to correct genetic errors that affect protein production.

18 Aug 2020

Manipulating cancer cell metabolism may help combat DIPGs and other brain tumors

Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures.

18 Aug 2020

Gene editing approach removes oral herpes

Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes.

18 Aug 2020

Study shows how bacteria become increasingly infectious under certain conditions

Bacteria that invade animal cells in order to multiply are widespread in nature. Some of these are pathogens of humans and animals. In the environment, they are often found inside unicellular organisms.

18 Aug 2020

Combination therapy effective for patients with cholangiocarcinoma marked by BRAF mutations

In a Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center, the combination of dabrafenib, a BRAF inhibitor, and trametinib, a MEK inhibitor, achieved a 51% overall response rate (ORR) in patients with cholangiocarcinoma marked by the BRAF V600E mutation.

18 Aug 2020

Researchers identify shared molecular roots between lipid dysfunction and autism

Researchers at Harvard Medical School, Massachusetts Institute of Technology and Northwestern University have identified a subtype of autism arising from a cluster of genes that regulate cholesterol metabolism and brain development.

18 Aug 2020

Study reports potential therapeutic target for lethal heart defect in children

When children are born with hypoplastic left heart syndrome (HLHS), they require a series of major surgical procedures to survive. But even with a repaired heart, as many as one in four children die from complications before age 25.

18 Aug 2020

Researchers solve a long-held mystery of X chromosome inactivation

Researchers at Massachusetts General Hospital (MGH) have solved a mystery that has long puzzled scientists: How do the bodies of female humans and all other mammals decide which of the two X chromosomes it carries in each cell should be active and which one should be silent?

18 Aug 2020

Gene News and Research

Latest Gene News and Research

Study could help understand the evolution of nervous systems in animals and humans

Study indicates a potential link between Alzheimer's and common brain disorder

Researchers identify mechanism that explains lower-quality immune response in COVID-19 patients

Adaptions to aging may be impacted by genetic background

Genomics study shows multiple and diverse SARS-CoV-2 introductions in the US capital region

New database could speed the development of gene-targeted therapies for breast cancer

New approach to chronic pain treatment could bring relief

Study investigates onset of spinocerebellar ataxia associated with loss of motor coordination

Single-dose adenovirus-vectored vaccine protects mice against SARS-CoV-2

Study identifies key gene as future therapeutic target for aggressive endometrial cancer

Antibody and cellular immunity in severe vs. mild COVID-19

Study shows how common drug paralyzes the parasites that cause elephantiasis

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

Manipulating cancer cell metabolism may help combat DIPGs and other brain tumors

Gene editing approach removes oral herpes

Study shows how bacteria become increasingly infectious under certain conditions

Combination therapy effective for patients with cholangiocarcinoma marked by BRAF mutations

Researchers identify shared molecular roots between lipid dysfunction and autism

Study reports potential therapeutic target for lethal heart defect in children

Researchers solve a long-held mystery of X chromosome inactivation

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging