Gene News and Research

Latest Gene News and Research

Biodegradable microcapsules loaded with nerve growth factor can guide neuronal development

Researchers from Skoltech and their colleagues have demonstrated that nanoengineered biodegradable microcapsules can guide the development of hippocampal neurons in an in vitro experiment.

16 Feb 2021

Study outlines the reasons to test pediatric cancer patients for inherited genes

Because cancers in children are rare, many details about their biology remain unknown. In the field of cancer genetics, there's a limited understanding of how inherited genetic changes may contribute to the formation and growth of tumors.

16 Feb 2021

Kruppel-like factor 15 controls skeletal muscle fat uptake and utilization

Metabolic diseases, such as obesity and type 2 diabetes, have risen to epidemic proportions in the U.S. and occur in about 30 percent of the population. Skeletal muscle plays a prominent role in controlling the body's glucose levels, which is important for the development of metabolic diseases like diabetes.

16 Feb 2021

Elevated Activin A and FLRG levels correlate with worst outcomes in severe COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes a "cytokine storm" in hospitalized and ICU patients. Studies have shown that the blockade of cytokine signaling and steroid treatment helps achieve positive outcomes in patients.

15 Feb 2021

Genetic testing technology wrongly detects the presence of very rare genetic variants

A technology that is widely used by commercial genetic testing companies is "extremely unreliable" in detecting very rare variants, meaning results suggesting individuals carry rare disease-causing genetic variants are usually wrong, according to new research published in the BMJ.

15 Feb 2021

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders.

15 Feb 2021

Research shows how chemicals in the tumor microenvironment enable cancer to evade attack

A paper published today in Nature shows how chemicals in the areas surrounding tumors--known as the tumor microenvironment--subvert the immune system and enable cancer to evade attack. These findings suggest that an existing drug could boost cancer immunotherapy.

15 Feb 2021

Scientists discover new immunotherapy target for malignant brain tumors

Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system.

15 Feb 2021

RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

A new study by researchers at the University of Connecticut Health Center, USA, reports the crucial nature of the pathogen pattern recognition receptor (PRRs), especially the two RLRs, retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5), in triggering host cell immune responses within the cell. The RLRs are viral RNA sensors.

15 Feb 2021

High-throughput sequencing could allow detection of new SARS-CoV-2 variants in wastewater

A new study reports the use of metagenomics to detect the virus from wastewater samples, indicating community-level circulating variants that are not yet identified or are present in very low proportions on clinical databases.

15 Feb 2021

Researchers study host and viral transcriptomes in tandem to shed light on SARS-CoV-2 infection

In a new study, researchers discuss the use of simultaneous sequencing of both human and viral genes to better understand SARS-CoV-2's infection pathway.

15 Feb 2021

A machine learning approach to identify drugs that could be repurposed to fight COVID-19

When the Covid-19 pandemic struck in early 2020, doctors and researchers rushed to find effective treatments. There was little time to spare.

15 Feb 2021

Naïve B cells can neutralize SARS-CoV-2 via RBD recognition

A new preprint research paper posted to the bioRxiv server demonstrates the potential of using the pre-existing protective responses to produce a broad-spectrum neutralizing response against not just SARS-CoV-2 but other future pathogens.

14 Feb 2021

New mouse model of SARS-CoV-2 infection reflects features of human infection

Now, a new preprint research paper posted to the bioRxiv server reports the development of a modified mouse model that allows productive SARS-CoV-2 infection of the mouse lungs, as well as the exploration of type I and III interferon responses in this condition.

14 Feb 2021

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

Researchers at Icahn School of Medicine at Mount Sinai in New York have provided evidence suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – was infecting people in New York City (NYC) at least one month before the first case was officially documented in the city.

14 Feb 2021

Scientists identify genes involved in autoimmune Addison's disease

Novel genetic associations could pave the way for early interventions and personalized treatment of an incurable condition.

13 Feb 2021

LMU researchers study T cell exhaustion

T lymphocytes, or T cells, are an important component of our immune system. They can recognize foreign proteins, so-called antigens, as peptide fragments - for instance, those derived from viruses or cancer cells.

13 Feb 2021

Study reveals mechanisms behind sensitivity of multiple myeloma cells to EZH2 inhibition

Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma.

13 Feb 2021

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

Tumor cells are able to avoid the attack of the immune system through several mechanisms. For instance, these can secrete factors that turn macrophages -cells in the immune system- into dual action agents that contribute to the tumor progress and will protect it from immune body defenses: these become, thus, the tumor-associated macrophages (TAMs).

13 Feb 2021

Novel finding could lead to better treatments for Type 1 and Type 2 diabetes

Monash University researchers have uncovered the barrier to β-cell (beta cell) regeneration that could pave the way for improved treatments for diabetes and diseases that involve organ and tissue damage.

12 Feb 2021

Gene News and Research

Latest Gene News and Research

Biodegradable microcapsules loaded with nerve growth factor can guide neuronal development

Study outlines the reasons to test pediatric cancer patients for inherited genes

Kruppel-like factor 15 controls skeletal muscle fat uptake and utilization

Elevated Activin A and FLRG levels correlate with worst outcomes in severe COVID-19

Genetic testing technology wrongly detects the presence of very rare genetic variants

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

Research shows how chemicals in the tumor microenvironment enable cancer to evade attack

Scientists discover new immunotherapy target for malignant brain tumors

RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

High-throughput sequencing could allow detection of new SARS-CoV-2 variants in wastewater

Researchers study host and viral transcriptomes in tandem to shed light on SARS-CoV-2 infection

A machine learning approach to identify drugs that could be repurposed to fight COVID-19

Naïve B cells can neutralize SARS-CoV-2 via RBD recognition

New mouse model of SARS-CoV-2 infection reflects features of human infection

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

Scientists identify genes involved in autoimmune Addison's disease

LMU researchers study T cell exhaustion

Study reveals mechanisms behind sensitivity of multiple myeloma cells to EZH2 inhibition

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

Novel finding could lead to better treatments for Type 1 and Type 2 diabetes

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)