Gene News and Research

Latest Gene News and Research

New AI-based method of image analysis finds new cell types in tissue

In situ sequencing enables gene activity inside body tissues to be depicted in microscope images. To facilitate interpretation of the vast quantities of information generated, Uppsala University researchers have now developed an entirely new method of image analysis.

19 Oct 2020

Researchers discover gene that may help the body sense a full urinary bladder

In a National Institutes of Health (NIH)-funded study involving both mice and patients who are part of an NIH Clinical Center trial, researchers discovered that a gene, called PIEZO2, may be responsible for the powerful urge to urinate that we normally feel several times a day. The

19 Oct 2020

Cleveland Clinic joins new Center for Integrated Multi-Modal and Multi-Scale Nucleome Research

Cleveland Clinic has been named a participating institution for the newly established Center for Integrated Multi-Modal and Multi-Scale Nucleome Research, made possible by a recently awarded five-year, $6.5 million consortium grant from the National Institutes of Health Common Fund.

19 Oct 2020

Three new research teams aim to improve therapies for difficult-to-treat pediatric cancers

While incredible progress has been made in advancing pediatric cancer research, critical unmet needs still exist, especially for more aggressive cancers such as neuroblastomas and Ewing sarcoma.

19 Oct 2020

Cytotoxic NK cells also have immunological memory function

Good news for the human immune system: researchers from MedUni Vienna's Departments of Dermatology and Surgery have managed to ascribe an immunological memory function to a subset of cytotoxic NK cells, which have hitherto been regarded as antigen-non-specific.

19 Oct 2020

Study provides possible explanation for progressive course of multiple sclerosis in mice

People with multiple sclerosis gradually develop increasing functional impairment. Researchers at Karolinska Institutet in Sweden have now found a possible explanation for the progressive course of the disease in mice and how it can be reversed.

16 Oct 2020

Tracing lineage to demonstrate direct astrocyte-to-neuron conversion in mouse brain

Regeneration of functional new neurons to repair injured human brain is a long-term unsolved problem up till today.

16 Oct 2020

Researchers develop new strategy to improve siRNA stability

RNA interference is a gene regulatory mechanism in which the expression of specific genes is downregulated by endogenous microRNAs or by small interfering RNAs (siRNAs).

16 Oct 2020

Gene variants may provide clues to successful treatment of pediatric eosinophilic esophagitis

A group of three gene variants, commonly inherited together, may provide clues to more successful treatment of pediatric eosinophilic esophagitis (EoE), a chronic inflammation of the food pipe often confused with gastroesophageal reflux disease (GERD).

16 Oct 2020

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Synthego, the genome engineering company, has collaborated with The Krogan Lab, a world-renowned scientific research unit at the Quantitative Biosciences Institute (QBI) at the University of California, San Francisco (UCSF), to deliver multiple CRISPR-based engineered cell lines to accelerate the study of potential treatment targets for SARS-CoV-2, the novel coronavirus that causes COVID-19 disease.

16 Oct 2020

Patients with soft-tissue cancer show rapid and complete response to novel combination of immunotherapy

A patient with end-stage and rapidly progressing soft-tissue cancer whose tumor did not respond to standard treatment, had a "rapid and complete response" to a novel combination of immunotherapy, according to new research published by a team of scientists from John Theurer Cancer Center at Hackensack University Medical Center and the Georgetown Lombardi Comprehensive Cancer Center, both of whom are part of the Georgetown Lombardi Comprehensive Cancer Center Consortium.

16 Oct 2020

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

Now, a recent study published on the preprint server bioRxiv in October 2020 reports the development of a rapid process for generating high-affinity mouse mAbs, and their functional attributes.

16 Oct 2020

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Why are some people more resilient to viruses than others? The answer has eluded scientists for centuries and, in the age of COVID-19, has come to represent one of the holy grails of biomedical research.

16 Oct 2020

Synthetic signals could help control tissue regeneration, guide cellular therapies

For a tiny embryo to develop into an adult organism, its cells must develop in precise patterns and interact with their neighbors in carefully orchestrated ways.

16 Oct 2020

Early trauma leads to changes in blood metabolites, study finds

A study by the Brain Research Institute at UZH reveals that early trauma leads to changes in blood metabolites - similarly in mice and humans.

15 Oct 2020

NIH grants 4D Nucleome award to support research by Gladstone scientists

The National Institutes of Health has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, PhD, and Katie Pollard, PhD.

15 Oct 2020

UTHSC professor receives $2.2 million for research into arterial stiffness and hypertension

In humans, large arteries lose elasticity and thicken with age and other pathological conditions, leading to arteriosclerosis and high blood pressure.

15 Oct 2020

Moffitt study uncovers how specific molecules promote cancer progression

The development of cancer is a highly complicated process, involving multiple genes and signaling pathways that become upregulated or downregulated throughout different stages of tumor growth and spread.

15 Oct 2020

UCI-led researchers receive $3 million NIH grant for 4D Nucleome project

The National Institutes of Health has awarded a team of researchers, led by the University of California, Irvine's Xiangmin Xu, PhD, a five-year, $3 million grant for a project titled, "Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus."

15 Oct 2020

Small molecule restores normal heart development in animal model with rare genetic disorder

A research team at the Greenwood Genetic Center has successfully used small molecules to restore normal heart and valve development in an animal model for Mucolipidosis II (ML II), a rare genetic disorder. Progressive heart disease is commonly associated with ML II.

15 Oct 2020

Gene News and Research

Latest Gene News and Research

New AI-based method of image analysis finds new cell types in tissue

Researchers discover gene that may help the body sense a full urinary bladder

Cleveland Clinic joins new Center for Integrated Multi-Modal and Multi-Scale Nucleome Research

Three new research teams aim to improve therapies for difficult-to-treat pediatric cancers

Cytotoxic NK cells also have immunological memory function

Study provides possible explanation for progressive course of multiple sclerosis in mice

Tracing lineage to demonstrate direct astrocyte-to-neuron conversion in mouse brain

Researchers develop new strategy to improve siRNA stability

Gene variants may provide clues to successful treatment of pediatric eosinophilic esophagitis

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Patients with soft-tissue cancer show rapid and complete response to novel combination of immunotherapy

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Synthetic signals could help control tissue regeneration, guide cellular therapies

Early trauma leads to changes in blood metabolites, study finds

NIH grants 4D Nucleome award to support research by Gladstone scientists

UTHSC professor receives $2.2 million for research into arterial stiffness and hypertension

Moffitt study uncovers how specific molecules promote cancer progression

UCI-led researchers receive $3 million NIH grant for 4D Nucleome project

Small molecule restores normal heart development in animal model with rare genetic disorder

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