Gene News and Research

Latest Gene News and Research

Targeted therapy achieves durable objective responses Phase I/II LIBRETTO-001 trial

For patients with non-small cell lung cancers (NSCLC) marked by RET gene fusions, the targeted therapy selpercatinib was well tolerated and achieved durable objective responses, or tumor shrinkage, in the majority of participants in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center.

27 Aug 2020

New group of Chlamydiae have hydrogen-producing genes that help them survive without oxygen

An international team of researchers has discovered a new group of Chlamydiae - Anoxychlamydiales - living under the ocean floor without oxygen.

27 Aug 2020

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

A Cambridge-developed DNA vaccine candidate against SARS-CoV-2 could begin clinical trials in the UK in late autumn or early next year, thanks to a £1.9 million award from the UK government.

27 Aug 2020

Targeting a key gateway can help treat chronic pain, shows study

Something like a quarter of the world's population suffers from chronic pain at some point. As opposed to acute pain – for example, that feeling after hitting your finger with a hammer – chronic pain may not even have a clear cause, and it can linger for years or lifetimes.

27 Aug 2020

Blood test can help predict who is likely to develop psychotic disorders

Scientists have discovered that testing the levels of certain proteins in blood samples can predict whether a person at risk of psychosis is likely to develop a psychotic disorder years later.

26 Aug 2020

Study offers hope for treatment of Krabbe disease

In one out of 100,000 infants, a mutation in the GALC gene causes an incurable, always fatal disorder known as infantile Krabbe disease, or globoid cell leukodystrophy. Most children with the condition die before they turn 2.

26 Aug 2020

Novel cell-based therapy holds promise for obesity and diabetes

Obesity is the main cause of type 2 diabetes and related chronic illnesses that together will kill more people around the globe this year than the Covid-19 coronavirus.

26 Aug 2020

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease.

26 Aug 2020

Scientists discover possible biomarkers for detecting opioid use disorder during pregnancy

Scientists at the University of Missouri have discovered possible biological markers that they hope could one day help identify the presence of an opioid use disorder during human pregnancy.

26 Aug 2020

Largely ignored 'housekeeping' gene plays a role in seizures

Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.

26 Aug 2020

New computational methods help find genetic causes of severe childhood brain disorders

A team of researchers at Children's Hospital of Philadelphia affiliated with the CHOP Epilepsy Neurogenetics Initiative have combined clinical information with large-scale genomic data to successfully link characteristic presentations of childhood epilepsies with specific genetic variants.

26 Aug 2020

Exosomes: The cancer cell communication mechanism

Professor Deborah Goberdhan speaks to News-Medical about her team's latest research into cancer cells, and the mechanisms they use to communicate.

26 Aug 2020

Estradiol appears to help in female SARS-CoV-2 infection

A new study published on the preprint server medRxiv in August 2020 shows that the risk of infection is high for pre-menopausal women but the risk of death is much higher for men in the same age group and throws light on the protective nature of estradiol therapy in post-menopausal women.

26 Aug 2020

Identifying COVID-19 host genes using symptom-based predictions

A recent study published on the preprint server bioRxiv* in August 2020 shows that symptom-based prediction of the diagnosis can help identify host genes that are responsible for part of this variability.

26 Aug 2020

Personalized genetic testing helps reduce adverse events following balloon angioplasty

An international, first-of-its-kind cardiology trial used personalized genetic testing to reduce by 34 per cent the number of serious adverse events following balloon angioplasty, a treatment for the most common form of heart disease.

26 Aug 2020

Synthetic gene fragments from SARS-CoV-2 can help produce accurate diagnostic tests

Researchers at the National Institute of Standards and Technology (NIST) have produced synthetic gene fragments from SARS-CoV-2, the virus that causes COVID-19. This material, which is non-infectious and safe to handle, can help manufacturers produce more accurate and reliable diagnostic tests for the disease.

26 Aug 2020

Gene News and Research

Latest Gene News and Research

Targeted therapy achieves durable objective responses Phase I/II LIBRETTO-001 trial

New group of Chlamydiae have hydrogen-producing genes that help them survive without oxygen

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

Targeting a key gateway can help treat chronic pain, shows study

Blood test can help predict who is likely to develop psychotic disorders

Study offers hope for treatment of Krabbe disease

Novel cell-based therapy holds promise for obesity and diabetes

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

Scientists discover possible biomarkers for detecting opioid use disorder during pregnancy

Largely ignored 'housekeeping' gene plays a role in seizures

New computational methods help find genetic causes of severe childhood brain disorders

Exosomes: The cancer cell communication mechanism

Estradiol appears to help in female SARS-CoV-2 infection

Identifying COVID-19 host genes using symptom-based predictions

Personalized genetic testing helps reduce adverse events following balloon angioplasty

Synthetic gene fragments from SARS-CoV-2 can help produce accurate diagnostic tests

Study examines safety and early outcomes of gene therapy for spinal muscular atrophy

Advances in Virus Epigenetics

Inhaled steroids reduce SARS-CoV-2-related genes in COPD

Study examines potential therapeutic approach for Alzheimer's disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging