Gene News and Research

Latest Gene News and Research

Inherited DNA defects cause squamous cell carcinoma in kids with Fanconi anemia

Physicians and scientists at Cincinnati Children's Hospital Medical Center used new stem cell technology to regenerate and study living patient-specific skin in the lab.

24 Nov 2020

Researchers develop new search engine to investigate viral sequences in COVID-19

Since the beginning of 2020, labs from all around the world are sequencing the material from positive tests of people affected by COVID-19 and then depositing sequences mostly to three points of collection: GenBank, COG-UK, and GISAID.

23 Nov 2020

Study shows BICRA gene functions in neural development in humans, flies

Physicians and scientists are constantly on the lookout for new disease genes that can help them understand why patients have undiagnosed medical problems.

23 Nov 2020

New link found between Alzheimer's dementia and Dlgap2 gene

A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer's dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine.

23 Nov 2020

Favorable clinical outcome for ivermectin in COVID-19 animal model

A team of researchers at the Institut Pasteur in France has found that ivermectin prevented clinical deterioration in infected animals. The drug also reduced the inflammatory cytokines, interleukin-6 and 10 (IL-6 and IL-10) in lung tissue, which leads to more favorable clinical outcomes in treated animals.

23 Nov 2020

University of Sheffield and Pfizer launch new consortium to accelerate development of ATMPs

The University of Sheffield and Pfizer have today (23 November 2020) launched a new consortium which aims to standardize and accelerate the development of Advanced Therapy Medicinal Products (ATMPs), allowing potentially transformative treatments to reach patients sooner.

23 Nov 2020

UNC scientists find brain cells that help drive arousal responses to strong emotions

Strong emotions such as fear and anxiety tend to be accompanied and reinforced by measurable bodily changes including increased blood pressure, heart rate and respiration, and dilation of the eyes' pupils. These so-called "physiological arousal responses" are often abnormally high or low in psychiatric illnesses such as anxiety disorders and depression.

23 Nov 2020

SARS-CoV-2's spike protein mutations have slowed, study finds

A team of researchers at the School of Information Sciences in Illinois, USA, has revealed the rate of mutation in the 29 proteins that make up the SARS-CoV-2 microbe.

23 Nov 2020

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

A thought-provoking new study reports that the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibodies elicited by natural infection may not be able to neutralize emerging strains that display deletion mutations in their genomic RNA.

23 Nov 2020

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects.

23 Nov 2020

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Researchers have developed a fluorescent reporter gene-bearing recombinant form of SARS-CoV-2, which is capable of replication.

23 Nov 2020

Research can bring new possibilities for earlier diagnosis, preventive treatment of dementia

Researchers at Karolinska Institutet in Sweden have studied the incidence and regional distribution of Alzheimer's disease biomarkers in the brains of people with Down's syndrome.

23 Nov 2020

Basic concepts lay the foundation for personalized immunotherapy

Personalized Immunotherapy for Tumor Diseases and Beyond introduces personalized immunotherapy with multi-dimensional models of analysis to determine the best plan for the immunotherapy of patients.

23 Nov 2020

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

20 Nov 2020

Researchers discover potential cellular target for eliminating bone breakdown in osteoporosis

New research has discovered a cell type that governs the way bones form and maintain themselves, opening up a potential target for future therapies for bone disorders like osteoporosis.

20 Nov 2020

New findings could pave the way for more effective, safer and cheaper gene therapy

In a promising advance for affordable, personalized medicine, researchers have used metal-organic frameworks to successfully deliver the genetic snipping tool CRISPR/Cas9 into human cancer cells.

20 Nov 2020

UVA researchers discover gene responsible for the metastasis of triple-negative breast cancer

University of Virginia Cancer Center researchers have identified a gene responsible for the spread of triple-negative breast cancer to other parts of the body - a process called metastasis - and developed a potential way to stop it.

20 Nov 2020

SARS-CoV-2 suppresses ACE2 activity in COVID-19 patients

A recent study conducted by a team of international scientists has revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19), suppresses the expression and function of human angiotensin-converting enzyme 2 (ACE2) and induces the expression of interferon-stimulated genes at the initial phase of infection. The study is currently available on the bioRxiv* preprint server.

20 Nov 2020

Furin inhibition may mitigate severe COVID-19, study finds

Dr. Kara Fitzgerald, a researcher at the Institute for Functional Medicine in the United States, has explained the role of furin protease in developing severe COVID-19 illness.

20 Nov 2020

New method of repairing damage to optic nerve offers hope for people with glaucoma-related sight loss

Fight for Sight funded researchers have successfully demonstrated a new method of repairing damage to the optic nerve in the lab for the first time, in new research that hopes to restore vision to those who’ve lost it as a result of glaucoma and other conditions.

20 Nov 2020

Gene News and Research

Latest Gene News and Research

Inherited DNA defects cause squamous cell carcinoma in kids with Fanconi anemia

Researchers develop new search engine to investigate viral sequences in COVID-19

Study shows BICRA gene functions in neural development in humans, flies

New link found between Alzheimer's dementia and Dlgap2 gene

Favorable clinical outcome for ivermectin in COVID-19 animal model

University of Sheffield and Pfizer launch new consortium to accelerate development of ATMPs

UNC scientists find brain cells that help drive arousal responses to strong emotions

SARS-CoV-2's spike protein mutations have slowed, study finds

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Research can bring new possibilities for earlier diagnosis, preventive treatment of dementia

Basic concepts lay the foundation for personalized immunotherapy

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

Researchers discover potential cellular target for eliminating bone breakdown in osteoporosis

New findings could pave the way for more effective, safer and cheaper gene therapy

UVA researchers discover gene responsible for the metastasis of triple-negative breast cancer

SARS-CoV-2 suppresses ACE2 activity in COVID-19 patients

Furin inhibition may mitigate severe COVID-19, study finds

New method of repairing damage to optic nerve offers hope for people with glaucoma-related sight loss

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)