Gene News and Research

Latest Gene News and Research

Cobra Biologics successfully produced master cell banks for CombiGene’s gene therapy

Cobra Biologics, part of the Cognate BioServices family, an international CDMO manufacturer of biological materials and pharmaceuticals, and CombiGene AB, the leading gene therapy company in the Nordic region, today announced that Cobra has successfully produced master cell banks for the three plasmids used as starting material for CombiGene’s gene therapy CG01.

21 Aug 2020

Bioinformatics identifies key genes and cellular pathways in COVID-19

The COVID-19 pandemic is showing no signs of waning or extinction anytime soon. Now, a new study published on the preprint server bioRxiv* in August 2020 shows a new bioinformatics approach to studying the pathogenesis of this disease, by uncovering the differentially expressed genes (DEGs) and cell signaling pathways that cause the disease characteristics. This will help develop better therapies to counter the effects of these genes.

20 Aug 2020

Combining expertise in organoids and sequencing technologies for ALS research

MDC researchers received a $150,000 pilot project grant from the Chan Zuckerberg Initiative's Neurodegeneration Challenge Network to investigate a defining feature of amyotrophic lateral sclerosis (ALS).

20 Aug 2020

Using engineered off-the-shelf therapeutic T cells to fight cancer

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors.

20 Aug 2020

Sortilin may hold the key to developing more effective treatment for pancreatic cancer

Pancreatic cancer has an extremely poor prognosis; it is the third most common cause of cancer deaths in the United States.

20 Aug 2020

Study may lead to novel therapies for asthma

Researchers identify master regulator genes of asthma, provide new path forward in the study of asthma and the development of novel therapies.

20 Aug 2020

Study shows why certain genetically predisposed individuals do not develop heart disease

Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can lead to elevated cholesterol and increased risk for a premature heart attack.

20 Aug 2020

Researchers develop vaccine for human herpesvirus 6B

A research group led by Professor MORI Yasuko (of the Division of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine) has revealed that the HHV-6B glycoprotein complex gH/gL/gQ1/gQ2 is an effective vaccine candidate for human herpesvirus 6B (HHV-6B).

20 Aug 2020

Study may lead to new targeted therapies that inhibit the spread of cancer

For decades, physicians have known that many kinds of cancer cells often spread first to lymph nodes before traveling to distant organs through the bloodstream.

20 Aug 2020

Study could help understand the evolution of nervous systems in animals and humans

When it comes to brain cells, one size does not fit all. Neurons come in a wide variety of shapes, sizes, and contain different types of brain chemicals. But how did they get that way?

20 Aug 2020

Study indicates a potential link between Alzheimer's and common brain disorder

Alzheimer's disease is one of the most common causes of dementia, and while most people might know someone who is affected by it, the genetic factors behind the disease are less known.

20 Aug 2020

Researchers identify mechanism that explains lower-quality immune response in COVID-19 patients

The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19.

20 Aug 2020

Adaptions to aging may be impacted by genetic background

How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside.

19 Aug 2020

Genomics study shows multiple and diverse SARS-CoV-2 introductions in the US capital region

A recent study led by the researchers from Johns Hopkins University reveals multiple and diverse introductions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the United States National Capital Region during the initial phase of coronavirus disease 2019 (COVID-19) pandemic. The study is currently available on the medRxiv* preprint server.

19 Aug 2020

New database could speed the development of gene-targeted therapies for breast cancer

All current breast cancer drugs were first tested in cell lines. Each cell line began as cancer in a patient. As such, each cell line is a surrogate for that patient's disease.

19 Aug 2020

New approach to chronic pain treatment could bring relief

Something like a quarter of the world's population suffers from chronic pain at some point in their lives. As opposed to acute pain - for example, the feeling after hitting your finger with a hammer - chronic pain may not even have a clear cause, and it can linger for years or lifetimes.

19 Aug 2020

Study investigates onset of spinocerebellar ataxia associated with loss of motor coordination

A European research alliance tracks the onset of ataxias "Spinocerebellar ataxias" are diseases of the nervous system associated with a loss of motor coordination.

19 Aug 2020

Single-dose adenovirus-vectored vaccine protects mice against SARS-CoV-2

The researchers selected the human adenovirus type 5 on which to base their vaccine because this replication-defective vector had already been used in their Ebola vaccine, with an excellent safety and immunogenicity profile in a phase 1 trial. The current study aimed to produce a vaccine that could offer mucosal vaccination and enhanced protection against this respiratory virus.

19 Aug 2020

Study identifies key gene as future therapeutic target for aggressive endometrial cancer

A new study has identified a key gene in aggressive endometrial cancer, which could lead to a targeted therapeutic strategy to improve survival rates.

19 Aug 2020

Antibody and cellular immunity in severe vs. mild COVID-19

Now, a new study published in the journal Signal Transduction and Targeted Therapy in August 2020 shows that while humoral and T-cell immune responses are more robust in severe infection, the disease activates memory T cells as part of the adaptive immune system in COVID-19 patients irrespective of disease severity.

18 Aug 2020

Gene News and Research

Latest Gene News and Research

Cobra Biologics successfully produced master cell banks for CombiGene’s gene therapy

Bioinformatics identifies key genes and cellular pathways in COVID-19

Combining expertise in organoids and sequencing technologies for ALS research

Using engineered off-the-shelf therapeutic T cells to fight cancer

Sortilin may hold the key to developing more effective treatment for pancreatic cancer

Study may lead to novel therapies for asthma

Study shows why certain genetically predisposed individuals do not develop heart disease

Researchers develop vaccine for human herpesvirus 6B

Study may lead to new targeted therapies that inhibit the spread of cancer

Study could help understand the evolution of nervous systems in animals and humans

Study indicates a potential link between Alzheimer's and common brain disorder

Researchers identify mechanism that explains lower-quality immune response in COVID-19 patients

Adaptions to aging may be impacted by genetic background

Genomics study shows multiple and diverse SARS-CoV-2 introductions in the US capital region

New database could speed the development of gene-targeted therapies for breast cancer

New approach to chronic pain treatment could bring relief

Study investigates onset of spinocerebellar ataxia associated with loss of motor coordination

Single-dose adenovirus-vectored vaccine protects mice against SARS-CoV-2

Study identifies key gene as future therapeutic target for aggressive endometrial cancer

Antibody and cellular immunity in severe vs. mild COVID-19

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research