Gene News and Research

Latest Gene News and Research

New cellular pathway protects cells from infection by Ebola virus, coronaviruses

Discoveries from the Benaroya Research Institute at Virginia Mason (BRI) have identified a new cellular protection pathway that targets a common vulnerability in several different pandemic viruses, and collaborators at Case Western Reserve University, Boston University School of Medicine and MRIGlobal have shown that this pathway can protect cells from infection by Ebola virus and coronaviruses, like SARS-CoV-2.

28 Aug 2020

Researchers identify RNA molecule that aids in lung cancer immune evasion

Researchers in Spain have identified a non-coding RNA molecule that helps lung cancer cells proliferate and avoid being killed by the body's immune cells.

27 Aug 2020

New low-cost COVID-19 test quickly delivers accurate results

A new low-cost diagnostic test for coronavirus disease 2019 (COVID-19) quickly delivers accurate results without the need for sophisticated equipment, according to a study published August 27 2020 in the open-access journal PLOS Pathogens by Teng Xu of the Vision Medicals Center for Infectious Diseases, Tieying Hou of the Guangdong Academy of Medical Sciences, Bing Gu of the Affiliated Hospital of Xuzhou Medical University, Jianwei Wang of the Chinese Academy of Medical Sciences and Peking Union Medical College, and colleagues.

27 Aug 2020

Researchers discover how brain cancer cells evade the body's immune system

Researchers in China have discovered how brain cancer cells increase production of a key protein that allows them to evade the body's immune system.

27 Aug 2020

Two viral gene targets needed in SARS-CoV-2 detection by PCR, say researchers

Researchers at the Chan Zuckerberg Biohub, San Francisco, and collaborators have warned against only targeting one viral gene when carrying out reverse transcriptase-polymerase chain reaction (RT-PCR) testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Aug 2020

First lethal mouse model of SARS-CoV-2 developed

Army scientists have developed the first lethal mouse model of SARS-CoV-2, the virus that causes COVID-19, using mice that were genetically engineered to express the human ACE2 gene--a key mechanism by which the virus enters human cells.

27 Aug 2020

Researchers find link between dystrophic muscles and lymphatic system in mice with Duchenne disease

Researchers at the Universities of Maynooth and Bonn discover a new connection in muscular dystrophy Duchenne muscular dystrophy (DMD) is the most common muscle disease in children and is passed on by X-linked recessive inheritance.

27 Aug 2020

New sequencing approach can detect rare mutation in large number of cells

A sequencing approach can home in on a rare mutation within a large number of cells, revealing implications for CRISPR genome editing and early cancer detection.

27 Aug 2020

A powerful tool for separation and sizing of virus mixtures

Postnova Analytics has published an applications report that presents data from a collaboration with the Analytical Development group at Biogen Inc. on separation of a virus mixture using Asymmetrical Flow Field-Flow Fractionation and measurement of their radius of gyration.

From Postnova Analytics 27 Aug 2020

Targeted therapy achieves durable objective responses Phase I/II LIBRETTO-001 trial

For patients with non-small cell lung cancers (NSCLC) marked by RET gene fusions, the targeted therapy selpercatinib was well tolerated and achieved durable objective responses, or tumor shrinkage, in the majority of participants in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center.

27 Aug 2020

New group of Chlamydiae have hydrogen-producing genes that help them survive without oxygen

An international team of researchers has discovered a new group of Chlamydiae - Anoxychlamydiales - living under the ocean floor without oxygen.

27 Aug 2020

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

A Cambridge-developed DNA vaccine candidate against SARS-CoV-2 could begin clinical trials in the UK in late autumn or early next year, thanks to a £1.9 million award from the UK government.

27 Aug 2020

Targeting a key gateway can help treat chronic pain, shows study

Something like a quarter of the world's population suffers from chronic pain at some point. As opposed to acute pain – for example, that feeling after hitting your finger with a hammer – chronic pain may not even have a clear cause, and it can linger for years or lifetimes.

27 Aug 2020

Blood test can help predict who is likely to develop psychotic disorders

Scientists have discovered that testing the levels of certain proteins in blood samples can predict whether a person at risk of psychosis is likely to develop a psychotic disorder years later.

26 Aug 2020

Study offers hope for treatment of Krabbe disease

In one out of 100,000 infants, a mutation in the GALC gene causes an incurable, always fatal disorder known as infantile Krabbe disease, or globoid cell leukodystrophy. Most children with the condition die before they turn 2.

26 Aug 2020

Novel cell-based therapy holds promise for obesity and diabetes

Obesity is the main cause of type 2 diabetes and related chronic illnesses that together will kill more people around the globe this year than the Covid-19 coronavirus.

26 Aug 2020

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease.

26 Aug 2020

Scientists discover possible biomarkers for detecting opioid use disorder during pregnancy

Scientists at the University of Missouri have discovered possible biological markers that they hope could one day help identify the presence of an opioid use disorder during human pregnancy.

26 Aug 2020

Largely ignored 'housekeeping' gene plays a role in seizures

Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.

26 Aug 2020

New computational methods help find genetic causes of severe childhood brain disorders

A team of researchers at Children's Hospital of Philadelphia affiliated with the CHOP Epilepsy Neurogenetics Initiative have combined clinical information with large-scale genomic data to successfully link characteristic presentations of childhood epilepsies with specific genetic variants.

26 Aug 2020

Gene News and Research

Latest Gene News and Research

New cellular pathway protects cells from infection by Ebola virus, coronaviruses

Researchers identify RNA molecule that aids in lung cancer immune evasion

New low-cost COVID-19 test quickly delivers accurate results

Researchers discover how brain cancer cells evade the body's immune system

Two viral gene targets needed in SARS-CoV-2 detection by PCR, say researchers

First lethal mouse model of SARS-CoV-2 developed

Researchers find link between dystrophic muscles and lymphatic system in mice with Duchenne disease

New sequencing approach can detect rare mutation in large number of cells

A powerful tool for separation and sizing of virus mixtures

Targeted therapy achieves durable objective responses Phase I/II LIBRETTO-001 trial

New group of Chlamydiae have hydrogen-producing genes that help them survive without oxygen

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

Targeting a key gateway can help treat chronic pain, shows study

Blood test can help predict who is likely to develop psychotic disorders

Study offers hope for treatment of Krabbe disease

Novel cell-based therapy holds promise for obesity and diabetes

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

Scientists discover possible biomarkers for detecting opioid use disorder during pregnancy

Largely ignored 'housekeeping' gene plays a role in seizures

New computational methods help find genetic causes of severe childhood brain disorders

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research