Gene News and Research

Latest Gene News and Research

Gene therapy reverses cardiac dysfunction in mice with Barth syndrome

Barth syndrome is a rare metabolic disease in boys caused by mutation of a gene called tafazzin or TAZ. It can cause life-threatening heart failure and also weakens the skeletal muscles, undercuts the immune response, and impairs overall growth.

9 Mar 2020

Scientists create new tool to study the genetic underpinnings of brain disorders

Scientists at the UNC School of Medicine and colleagues created a new computational tool called H-MAGMA to study the genetic underpinnings of nine brain disorders, including the identification of new genes associated with each disorder.

9 Mar 2020

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

Solute carriers represent the largest family of transmembrane transporters in the human genome, with over 400 members arranged into 65 families.

9 Mar 2020

Researchers uncover creeping, crawling origin of MYH9-related blood disorders

Ouch, you've cut your finger! As you fumble to grab a tissue, the paramedics in your blood are already rushing to the scene.

9 Mar 2020

Research sheds light on molecular mechanisms that enable bacteria to compete and establish symbiosis

Two factors that control the expression of a key gene required by luminescent bacteria to kill competing bacterial cells have been identified.

7 Mar 2020

Biomarker in saliva linked to emergence of childhood obesity

A molecular marker in saliva is associated with the emergence of childhood obesity in a group of preschool-aged Hispanic children.

7 Mar 2020

New technique to distinguish freshly made transcripts from pre-existing transcripts

Our bodies consist of trillions of cells that all contain the same DNA. Even though the DNA in each cell is the same, we consist of many different cell types, each with different functions.

6 Mar 2020

The Pancreatic Cancer Collective awards additional funding of $16 million for new therapies

The Pancreatic Cancer Collective, the strategic partnership of Lustgarten Foundation and Stand Up To Cancer, has awarded additional funding of up to $16 million to four teams of top researchers as part of its "New Therapies Challenge Grants," the American Association for Cancer Research, Scientific Partner of SU2C, announced today.

5 Mar 2020

Study provides new insight into neurofibromin-deficient ER+ breast cancer

An international team of researchers led by scientists at Baylor College of Medicine has new insights into the function of neurofibromin, a tumor suppressor produced by the NF1 gene.

5 Mar 2020

Newly identified genetic signatures in common pediatric cancer pave way for precision medicine

Researchers with Nemours Children's Health System utilized Next Generation Sequencing (NGS) to more precisely identify genomic characteristics of leukemias in children, the most common childhood cancer.

5 Mar 2020

X-ray free electron laser helps probe deeper into deadly pathogen

Tularemia is a rare but often lethal disease. It is caused by one of the most aggressive pathogens on earth, the bacterium Francisella tularensis.

5 Mar 2020

Researchers identify a gut microbe generated byproduct linked to cardiovascular disease

Cleveland Clinic researchers have identified a gut microbe generated byproduct - phenylacetylglutamine - that is linked to development of cardiovascular disease, including heart attack, stroke and death.

5 Mar 2020

Researchers uncover novel neurotransmitter system in the brain

Neurotransmitters are chemicals that transmit signals between neurons or from neurons to other cells. They interact with specific receptors found in the brain of humans and animals, controlling a variety of biological processes, e.g. fear, anger, pleasure, memory, energy, appetite and sleep.

5 Mar 2020

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response.

5 Mar 2020

Beating heart muscle tissues to be sent up to the microgravity environment of ISS

Launching no earlier than March 6 at 11:50 PM EST, the Johns Hopkins University will send heart muscle tissues, contained in a specially-designed tissue chip the size of a small cellphone, up to the microgravity environment of the International Space Station for one month of observation.

5 Mar 2020

Study provides new evidence about optimal way to treat BRCA carriers with breast cancer

Commonly known as the breast cancer genes, the BRCA gene family plays a role in repairing damaged DNA. Inherited mutations in the genes BRCA1 or BRCA2 raise the risk of developing breast, ovarian, prostate and other cancers.

5 Mar 2020

New repair mechanism for alcohol-induced DNA damage discovered

Researchers of the Hubrecht Institute in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol.

4 Mar 2020

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Ocugen, Inc., a clinical-stage company focused on discovering, developing and commercializing transformative therapies to treat rare and underserved ophthalmic diseases, announced today the publication in Nature Gene Therapy of preclinical data of nuclear hormone receptor gene NR2E3 as a genetic modifier and therapeutic agent to treat multiple retinal degenerative diseases.

3 Mar 2020

Chemists develop promising molecular tool to target cell immortality's underlying gears

One of the hallmarks of cancer is cell immortality. A Northwestern University organic chemist and his team now have developed a promising molecular tool that targets and inhibits one of cell immortality's underlying gears: the enzyme telomerase.

3 Mar 2020

UAB research reveals hydrogen sulfide as new culprit for deadly tuberculosis

A new culprit -- hydrogen sulfide -- has been found for the deadly infectious disease tuberculosis. Hydrogen sulfide gas is known for its rotten egg smell, yet it has normal physiological roles in the human body to communicate among cells.

3 Mar 2020

Gene News and Research

Latest Gene News and Research

Gene therapy reverses cardiac dysfunction in mice with Barth syndrome

Scientists create new tool to study the genetic underpinnings of brain disorders

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

Researchers uncover creeping, crawling origin of MYH9-related blood disorders

Research sheds light on molecular mechanisms that enable bacteria to compete and establish symbiosis

Biomarker in saliva linked to emergence of childhood obesity

New technique to distinguish freshly made transcripts from pre-existing transcripts

The Pancreatic Cancer Collective awards additional funding of $16 million for new therapies

Study provides new insight into neurofibromin-deficient ER+ breast cancer

Newly identified genetic signatures in common pediatric cancer pave way for precision medicine

X-ray free electron laser helps probe deeper into deadly pathogen

Researchers identify a gut microbe generated byproduct linked to cardiovascular disease

Researchers uncover novel neurotransmitter system in the brain

New type of adoptive cell therapy could target prostate and pancreatic cancers in humans

Beating heart muscle tissues to be sent up to the microgravity environment of ISS

Study provides new evidence about optimal way to treat BRCA carriers with breast cancer

New repair mechanism for alcohol-induced DNA damage discovered

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Chemists develop promising molecular tool to target cell immortality's underlying gears

UAB research reveals hydrogen sulfide as new culprit for deadly tuberculosis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging