Gene News and Research

Latest Gene News and Research

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

A team of researchers has come out with the first detailed map of the transcriptome and epitranscriptome of the virulent SARS-CoV-2 that causes COVID-19 disease, the illness that has become a pandemic ravaging both developed and less developed countries of the world. The study, published in the journal Cell in April 2020, may assist in the development of new vaccines and therapeutics.

12 Apr 2020

PARP inhibitor drugs can be structurally modified to better kill tumor cells

A prospective "PARP inhibitor" drug that has struggled to show effectiveness in clinical trials against cancers can be structurally modified to greatly increase its power to kill tumor cells, researchers from Penn Medicine report this week in Science.

12 Apr 2020

Researchers identify new risk gene for Parkinson's disease

Screening DNA of Parkinson's patients in the Christine Van Broeckhoven laboratory (VIB-UAntwerpen Center for Molecular Neurology) identified a new risk gene for Parkinson's disease. Mutations in ATP10B resulted in loss of ATP10B protein.

12 Apr 2020

Scientists make plant genome public to help combat COVID-19

Plant Nicotiana benthamiana is currently used as a bio-factory for several experimental vaccines against SARS-COV-2.

11 Apr 2020

Researchers pinpoint genetic variation responsible for development of IBD

Researchers at Children's Hospital of Philadelphia have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease.

9 Apr 2020

Combination of rare, damaging mutations negatively affects healthspan and longevity

Scientists report that the combined effects of rare, damaging mutations present at birth have a negative impact on healthspan and longevity, according to a study published this week in eLife.

9 Apr 2020

Researchers identify protein that plays critical role in cancer treatment-related heart damage

Many cancers can be successfully treated, but treatment itself often comes with risks as well. Cancer therapy that uses anthracyclines--a class of commonly used chemotherapy drugs--has been associated with heart damage that can eventually result in heart failure. It is thought to be the reason why heart disease is a leading cause of death in cancer survivors, immediately following cancer recurrence.

9 Apr 2020

Missing BAP1 gene renders immunotherapies ineffectual in uveal melanomas

New study from researchers in Finland and the United Kingdom reveals that tumors lacking a protein called BAP1 have an ineffective immune reaction against cancer, thus rendering immunotherapies ineffectual, particularly in uveal melanomas.

9 Apr 2020

Researchers discover novel role for dopamine that impacts gene expression related to cocaine abuse

A new role for dopamine independent of classic neurotransmission may be critical gene expression changes related to cocaine use.

9 Apr 2020

Novel coronavirus targets specific secretory cells in the lungs

Viruses attack specific host cells, which can cause chaos in the body. The novel coronavirus, now called severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 for short, infects respiratory epithelial cells in the lining of the lung, causing difficulty of breathing. The usual cause of death of those who contract the virus is pneumonia and acute respiratory distress syndrome (ARDS). Now, a new study has found that SARS-CoV-2 specifically attack certain progenitor cells called bronchial transient secretory cells in the lungs.

9 Apr 2020

LGC launches new proficiency testing program for SARS-CoV-2 detection

LGC today launched a Proficiency Testing service for the detection of SARS-CoV-2 (COVID 19) by nucleic acid amplification testing, one of the first global schemes for COVID-19.

From ATCC 9 Apr 2020

Smokers have more ACE2 receptors making it easier for SARS-CoV-2 to infect

A new study published in the European Respiratory Journal in April 2020 reveals that people with smoking-damaged lungs and those with chronic obstructive pulmonary disease (COPD) are likely to have a higher level of the angiotensin-converting enzyme II (ACE2).

9 Apr 2020

PIV5-based MERS vaccine shows promise for COVID-19

The coronavirus disease (COVID-19) has spread to 184 countries and territories. Currently, there is no vaccine available for COVID-19 disease, or SARS-CoV-2 infection. However, scientists around the world are racing to find ways to block the virus.

8 Apr 2020

Researchers develop online resource to refine results from RNA sequencing

DNA sequencing is becoming a more commonplace method for detecting diseases and improving precision medicine.

8 Apr 2020

Modifiable risk factors could play important role in Alzheimer's disease, study finds

Amyloid is a key feature of Alzheimer's disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer's disease, according to a new study published this week.

8 Apr 2020

World's largest protein connection map reveals cell workings

The human body is comprised of billions of cells. Yet it functions and grows as a single organism, because of trillions of interactions that help various cells recognize and respond to each other via different molecules on their surface or inside the cells. Now, a new study published in the journal Nature in April 2020 describes the first-ever interactome map, to help distinguish healthy interactions and disease-producing ones.

8 Apr 2020

Short-term exposure to even low levels of air pollution can affect gene expression

New data from a landmark study done by Monash University researchers in Australia raises significant concerns that even short-term exposure to low level air pollution can affect gene expression, leaving us at risk of other diseases such as cancer, cardiovascular and respiratory diseases.

8 Apr 2020

Cancer-causing mutation also promotes inflammation

Analyses of cell signals provide insight into the origin of severe inflammatory symptoms that appear in various types of blood cancer and point to possible therapeutic approaches: In around one-fourth of patients suffering from juvenile myelomonocytic leukemia, there is evidence of mutations in the so-called KRAS gene in the leukemia cells.

8 Apr 2020

World's largest map of protein connections holds clues to health and disease

Scientists have described the first reference map of interactions between gene-encoded proteins which make up cells.

8 Apr 2020

Wyatt Technology Pioneers Multi-CQA Method for Gene Vectors

Wyatt Technology, the world leader in instrumentation for absolute macromolecular and nanoparticle characterization, announces the release of a novel method suitable for determining multiple critical quality attributes of adeno-associated virus and similar small gene vectors, in a single chromatographic run.

From Waters | Wyatt Technology 8 Apr 2020

Gene News and Research

Latest Gene News and Research

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

PARP inhibitor drugs can be structurally modified to better kill tumor cells

Researchers identify new risk gene for Parkinson's disease

Scientists make plant genome public to help combat COVID-19

Researchers pinpoint genetic variation responsible for development of IBD

Combination of rare, damaging mutations negatively affects healthspan and longevity

Researchers identify protein that plays critical role in cancer treatment-related heart damage

Missing BAP1 gene renders immunotherapies ineffectual in uveal melanomas

Researchers discover novel role for dopamine that impacts gene expression related to cocaine abuse

Novel coronavirus targets specific secretory cells in the lungs

LGC launches new proficiency testing program for SARS-CoV-2 detection

Smokers have more ACE2 receptors making it easier for SARS-CoV-2 to infect

PIV5-based MERS vaccine shows promise for COVID-19

Researchers develop online resource to refine results from RNA sequencing

Modifiable risk factors could play important role in Alzheimer's disease, study finds

World's largest protein connection map reveals cell workings

Short-term exposure to even low levels of air pollution can affect gene expression

Cancer-causing mutation also promotes inflammation

World's largest map of protein connections holds clues to health and disease

Wyatt Technology Pioneers Multi-CQA Method for Gene Vectors

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting