Gene News and Research

Latest Gene News and Research

Discovery of novel mechanism by which certain breast cancers can metastasize

Researchers from the Baylor College of Medicine and Harvard Medical School have found a novel mechanism to explain the resistance of certain breast cancers that spread in the major organs of the body. They hope that this would help develop new therapeutic strategies to treat the cancer.

12 Dec 2019

Scientists develop an approach to vaccinate against gut inflammation

Inflammatory bowel disease (IBD) is an umbrella term that describes many disorders that involve chronic inflammation of the digestive tract, including ulcerative colitis and Crohn's disease. These conditions are tied to certain alternations in the gut flora.

12 Dec 2019

New insights into the most perplexing medical mysteries associated with schizophrenia

Four unsolved mysteries around schizophrenia have long plagued the medical community, but a new hypothesis identifying a common link between them and an almost forgotten epidemic of a disease called pellagra could have profound implications for our understanding of psychosis in poorer nations.

12 Dec 2019

Harvard scientists demonstrate possible strategy for achieving herpes virus control

The herpes simplex virus, commonly known as the cold sore virus, is a devious microbe.

12 Dec 2019

University Of Iowa wins $18 million grant to continue study on Huntington's disease

Peg Nopoulos, MD, chair of psychiatry and professor of psychiatry, neurology, and pediatrics in the University of Iowa Carver College of Medicine, has received a five-year, $18 million grant from the National Institute of Neurological Disorders and Stroke to continue and expand a decade-long study on brain development in children at risk for developing Huntington's Disease.

11 Dec 2019

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

UCLA scientists have discovered one reason why autoimmune diseases are more prevalent in women than in men.

11 Dec 2019

Gut disease and gene analysis networks

Gut diseases are difficult to diagnose in many cases, and their underlying dysfunction is hard to understand in many cases. Now, a new study published in the journal Molecular Omics promises to uncover a better insight into how these conditions occur and their mechanisms, by providing a deeper look at how genes interact in complex ways in health and fail to do so in disease.

11 Dec 2019

Epigenome editing could repair genetic brain disorder

A new study published in the journal Nature Communications shows that it may be possible to reverse gene mutations that cause brain disorders, using a very precisely targeted epigenome editing technique. This type of gene editing does not change the gene’s DNA sequence itself but is focused on correcting epigenome changes only. The condition that was corrected in the study is called the WAGR syndrome and is associated with obesity and intellectual disability in people.

11 Dec 2019

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings.

11 Dec 2019

Genetic code doesn't dictate whether a person is guaranteed to develop Alzheimer's

The colour of our eyes or the straightness of our hair is linked to our DNA, but the development of Alzheimer's disease isn't exclusively linked to genetics, suggest recently published findings.

11 Dec 2019

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies.

11 Dec 2019

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

The sweeping extent to which increasing 40Hz "gamma" rhythm power in the brain can affect the pathology and symptoms of Alzheimer's disease in mouse models has been surprising, even to the MIT neuroscientists who've pioneered the idea. So surprising, in fact, they can't yet explain why it happens.

11 Dec 2019

OGT develops targeted NGS panel for constitutional cytogenetics research

Oxford Gene Technology, A Sysmex Group Company, has developed a breakthrough targeted NGS panel for constitutional cytogenetics research. The new CytoSure NGS panel—launching early in 2020—will combine the strengths of microarrays and NGS to deliver a comprehensive all-in-one assay.

From Oxford Gene Technology 11 Dec 2019

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

A genetic variant in the gene transthyretin (TTR)- which is found in about 3 percent of individuals of African ancestry- is a more significant cause of heart failure than previously believed, according to a multi-institution study led by researchers at Penn Medicine.

10 Dec 2019

Online decision aid provides more knowledge about the benefits of genomic sequencing

A decision aid developed to support patients undergoing genomic sequencing can reduce the amount of time patients spend speaking with overburdened genetic counselors while helping them were more knowledgeable about the benefits of sequencing, suggests a study from St. Michael's Hospital.

10 Dec 2019

Huntington's disease patients need to better understand the risks and benefits of new therapies

For patients with Huntington's disease (HD), clinical trials can offer hope when there are no treatments available despite unknowns about whether the therapy will work or is safe.

10 Dec 2019

Researchers find another piece of puzzle relating to bird flu viruses

Normally, bird flu viruses do not spread easily from person to person. But if this does happen, it could trigger a pandemic. Researchers from the MDC and RKI have now explained in the journal Nature Communications what makes the leap from animals to humans less likely.

10 Dec 2019

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

10 Dec 2019

A network approach to explore the causes of IBD

Diseases of the gut are often notoriously difficult to diagnose, nevermind understand, which is where a network-based approach comes in.

10 Dec 2019

ERC promotes CRISPR research to better treat infections

Chase Beisel heads the "Synthetic Biology of RNA" research group at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a branch of the Helmholtz Centre for Infection Research in Braunschweig and run in collaboration with the Julius-Maximilians-Universität in Würzburg.

10 Dec 2019

Gene News and Research

Latest Gene News and Research

Discovery of novel mechanism by which certain breast cancers can metastasize

Scientists develop an approach to vaccinate against gut inflammation

New insights into the most perplexing medical mysteries associated with schizophrenia

Harvard scientists demonstrate possible strategy for achieving herpes virus control

University Of Iowa wins $18 million grant to continue study on Huntington's disease

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

Gut disease and gene analysis networks

Epigenome editing could repair genetic brain disorder

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

Genetic code doesn't dictate whether a person is guaranteed to develop Alzheimer's

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

OGT develops targeted NGS panel for constitutional cytogenetics research

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

Online decision aid provides more knowledge about the benefits of genomic sequencing

Huntington's disease patients need to better understand the risks and benefits of new therapies

Researchers find another piece of puzzle relating to bird flu viruses

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

A network approach to explore the causes of IBD

ERC promotes CRISPR research to better treat infections

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