Gene News and Research

Latest Gene News and Research

Study of gene network could lead to new treatment for different neurological disorders

A mutated gene found in people with intellectual disabilities that could be targeted for treatment has been identified by an international team including University of Queensland researchers.

5 Dec 2019

Scientists identify how damaged DNA molecules are repaired inside the human genome

A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its health and how it responds to diseases that stem from impaired DNA.

5 Dec 2019

Overabundance of novel gene in aggressive form of ovarian cancer may serve as prognostic tool

Investigators at Rutgers Cancer Institute of New Jersey have determined that an overabundance of a novel gene known as ADNP in an aggressive form of ovarian cancer may serve as a prognostic tool.

5 Dec 2019

Coriell scientist awarded grant to explore epigenetic drivers of breast cancer

Shoghag Panjarian, PhD, a research scientist at the Coriell Institute for Medical Research, has been awarded a grant from the W. W. Smith Charitable Trust to support her search for epigenetic factors that contribute to the development and growth of breast cancer.

5 Dec 2019

New discovery on chromosomal function may shed light on human health and disease

Researchers have discovered key mechanisms and structural details of a fundamental biological process - how a cell nucleus and its chromosomal material reorganizes itself after cell division

5 Dec 2019

ADDF announces new awards through its Diagnostics Accelerator initiative

The Alzheimer's Drug Discovery Foundation announced six new investments totaling $6 million through its Diagnostics Accelerator initiative.

4 Dec 2019

Epigenomic techniques used to fight disease

Humans differ from one another in many ways, including how they react to disease, because of their DNA blueprint, as well as the difference in the environments they face. These factors combine to make each person unique. Now a new study published in the journal Nature Protocols reports the development of a promising technology to uncover the process by which the body fights diseases in different ways.

4 Dec 2019

A major step toward preventing GvHD in patients receiving bone marrow transplants

A drug used for rheumatoid arthritis has moved a step closer to FDA approval for a desperately needed new use.

4 Dec 2019

Baylor researchers report creation of an 'epigenetic couch potato' mouse

Why is it that some people love to exercise, and others hate it? Most people would assume it's all due to genetics, but a new Baylor College of Medicine led study in mice shows for the first time that a different molecular level of regulation - epigenetics - plays a key role in determining one's innate drive to exercise.

4 Dec 2019

Early adherence step in intestinal transit of Shigella discovered

The bacterial pathogen Shigella, often spread through contaminated food or water, is a leading cause of mortality in both children and older adults in the developing world.

4 Dec 2019

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium.

4 Dec 2019

Experts condemn CRISPR babies research as original manuscript is made public

Scientists have criticized the gene-editing of the Chinese twins last year, following the first public release of the research.

4 Dec 2019

Study identifies improved treatment option for neuroblastoma

Neuroblastoma is a rare form of malignant tumor, primarily affecting children under the age of six. A research team led by molecular pathologist Lukas Kenner from MedUni Vienna's Department of Pathology has now discovered, through genome sequencing, that the protein ALK and the cancer gene PIM1 are involved in the development of this tumor.

4 Dec 2019

Why some sperm swim in circles – it’s a protein defect

A new study published in the journal PNAS shows that some sperm cannot swim straight because they lack a protein called VSP. This motility defect seriously impacts the rates of successful fertilization. In addition, VSP is also found to regulate the amount of calcium that enters the flagellum, the whiplike organelle that propels the sperm towards the waiting ovum or egg. This important discovery may help treat infertility more effectively.

3 Dec 2019

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Along with the promise that CRISPR-Cas9 gene editing technology can offer new human therapies is the need to ensure its safety. A recent study showed that CRISPR-Cas9 did not produce off-target gene mutations in zebrafish. These results, published in Frontiers in Genetics, confirm previous data in animal models that the risk to the rest of the genome from gene editing is minimal.

3 Dec 2019

Failure in proteasome transportation system may cause neurodegenerative diseases

All neurodegenerative diseases have a common thread: the appearance of protein clumps in the brain such as amyloid-beta plaques in Alzheimer's disease and alpha synuclein aggregates in Parkinson's.

3 Dec 2019

Researchers discover regulatory map of the human EphB4 gene

Pierluigi Scalia and coworkers at the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University in Philadelphia, and the affiliated Italian research organization ISOPROG, have announced the regulatory map of the human EphB4 gene.

3 Dec 2019

Early-morning, starch-rich meal improves glycemic control among type 2 diabetics

Type 2 diabetics inject themselves with insulin, a hormone that regulates the movement of sugar into liver, muscle and fat cells, up to four times a day. But insulin injections are linked to weight gain and the loss of control of blood sugar levels. This triggers a vicious cycle of higher insulin doses, continuous weight gain, a higher incidence of cardiovascular disease and other complications.

3 Dec 2019

Roswell Park-led scientists identify new defense mechanism against prostate cancer

A research team led by a scientist at Roswell Park Comprehensive Cancer Center has identified the molecule LRIG1 as an important endogenous tumor suppressor in prostate cancer. Writing in the journal Nature Communications, the team documents their findings from preclinical studies showing that overexpression of the LRIG1 protein inhibits prostate cancer development, while reducing naturally occurring LRIG1 promotes prostate tumor development.

3 Dec 2019

Freiburg scientists decipher basic molecular control mechanisms behind cellular identity

A research team headed by Prof. Dr. Sebastian Arnold and Jelena Tosic from the Faculty of Medicine at the University of Freiburg has now succeeded in deciphering basic molecular control mechanisms by which stem cells decide which embryonic cell types to turn into.

3 Dec 2019

Gene News and Research

Latest Gene News and Research

Study of gene network could lead to new treatment for different neurological disorders

Scientists identify how damaged DNA molecules are repaired inside the human genome

Overabundance of novel gene in aggressive form of ovarian cancer may serve as prognostic tool

Coriell scientist awarded grant to explore epigenetic drivers of breast cancer

New discovery on chromosomal function may shed light on human health and disease

ADDF announces new awards through its Diagnostics Accelerator initiative

Epigenomic techniques used to fight disease

A major step toward preventing GvHD in patients receiving bone marrow transplants

Baylor researchers report creation of an 'epigenetic couch potato' mouse

Early adherence step in intestinal transit of Shigella discovered

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

Experts condemn CRISPR babies research as original manuscript is made public

Study identifies improved treatment option for neuroblastoma

Why some sperm swim in circles – it’s a protein defect

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Failure in proteasome transportation system may cause neurodegenerative diseases

Researchers discover regulatory map of the human EphB4 gene

Early-morning, starch-rich meal improves glycemic control among type 2 diabetics

Roswell Park-led scientists identify new defense mechanism against prostate cancer

Freiburg scientists decipher basic molecular control mechanisms behind cellular identity

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Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research