Gene News and Research

Latest Gene News and Research

Salk researchers reveal clues into early development of ASD

Autism spectrum disorder is a relatively common developmental disorder of communication and behavior that affects about 1 in 59 children in the US, according to the Centers for Disease Control and Prevention. Despite its prevalence, it is still unclear what causes the disease and what are the best ways to treat it.

7 Jan 2019

Researchers identify genetic risk factor for atypical heart attack in women

New research published by teams from Leicester, UK and Paris, France in collaboration with international partners from the US and Australia, has found a common genetic factor that confers a significant risk of atypical heart attacks in women.

7 Jan 2019

Cellular protein signal can be manipulated to favor bone building

In experiments in rats and human cells, Johns Hopkins Medicine researchers say they have added to evidence that a cellular protein signal that drives both bone and fat formation in selected stem cells can be manipulated to favor bone building.

7 Jan 2019

USC research could lay foundation for a vaccine against tick-borne virus

Two groundbreaking discoveries by USC researchers could lead to medications and a vaccine to treat or prevent a hemorrhagic fever transmitted by a new tick species before it spreads across the United States.

7 Jan 2019

Study of rare uterine sarcoma reveals clinically relevant molecular subtypes

Undifferentiated uterine sarcoma is a very rare but extremely aggressive cancer type. It can be divided into four groups with different characteristics of clinical importance - a new study at Karolinska Institutet reveals.

7 Jan 2019

First viable mouse model of Hirschsprung's disease developed

About one in every 5,000 babies is born without enteric neurons in distal colon resulting in Hirschsprung's disease. Because of the lacking neurons, contents of the gut cannot pass normally resulting in constipation and enlargement of colon.

7 Jan 2019

Study elucidates how essential amino acid in humans acts as growth signal for cells

A recent study from the Laxman lab elucidates how a small metabolite and amino acid, methionine, acts as a growth signal for cells, by setting into motion a metabolic program for cell proliferation.

7 Jan 2019

GE Healthcare and VUMC announce partnership to enable safer, more precise cancer immunotherapies

GE Healthcare and Vanderbilt University Medical Center today announced a five-year partnership to enable safer and more precise cancer immunotherapies. Multiple diagnostic tools will be developed to help predict both the efficacy of an immunotherapy treatment and its adverse effects for a specific patient before the therapy is administered.

7 Jan 2019

Common food additive could cause celiac disease, review says

Research suggests that celiac disease could be caused by a bacterial enzyme used to manufacture sausages, cheese, bread and other processed foods.

7 Jan 2019

Research reveals factors at play in genetic incompatibility of different species

Most evolutionary biologists distinguish one species from another based on reproductivity: members of different species either won't or can't mate with one another, or, if they do, the resulting offspring are often sterile, unviable, or suffer some other sort of reduced fitness.

4 Jan 2019

Research illuminates abilities of ADAR1 to ‘hyper-mutate’ tumor suppressor RNAs in leukemia

Writing in the January 3 issue of Cancer Cell, researchers at University of California San Diego School of Medicine report that detection of "copy editing" by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, may provide a kind of molecular radar for early detection of malignancies and represent a new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.

3 Jan 2019

Bulldogs' screw tails linked to rare inherited syndrome in humans

With their small size, stubby faces and wide-set eyes, bulldogs, French bulldogs and Boston terriers are among the most popular of domestic dog breeds. Now researchers at the University of California, Davis, School of Veterinary Medicine have found the genetic basis for these dogs' appearance, and linked it to a rare inherited syndrome in humans.

3 Jan 2019

Study follows children into adolescence to more accurately assess type 1 diabetes risk

Scientists are narrowing in on checklists of both errant genes and the environmental factors that could trigger those genes to more accurately assess type 1 diabetes risk and help children and their families avoid it.

3 Jan 2019

Study: Mice lacking PARL protein display specific problems in the nervous system reminiscent of Leigh syndrome

Leuven researchers led by professor Bart De Strooper (VIB-KU Leuven) have identified a new role for PARL, a protein that has been linked to Parkinson's disease.

3 Jan 2019

Researchers identify genes that drive male-female brain differences, trigger initiation of puberty

Researchers have identified a group of genes that induces differences in the developing brains of male and female roundworms and triggers the initiation of puberty, a genetic pathway that may have the same function in controlling the timing of sual maturation in humans.

3 Jan 2019

Scientists cast new light on function of long-mysterious PCSK9 mutation

High levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading risk factor for heart disease. Many cholesterol medications lower LDL, some of them by targeting the protein PCSK9. In the January issue of the Journal of Lipid Research, scientists at the University of California, San Francisco, report on an investigation into why experiments on PCSK9 give different results in a test tube and in liver cells.

2 Jan 2019

Study provides new insights into how genes are activated

In a study in Nature, researchers at Karolinska Institutet present a new method for analyzing how instructions in the genome control how our genes are activated in individual cells.

2 Jan 2019

Rockefeller scientists uncover genetic mutation responsible for tuberculosis vulnerability

If you live in the United States, you are unlikely to come into contact with the microbe that causes tuberculosis. Your odds of encountering the microbe are so low, in fact, that risk factors for the disease can easily go unnoticed: If you happened to carry a gene that predisposed you to tuberculosis, you likely wouldn't know.

2 Jan 2019

Hyperactive immune system implicated in aging brain disorders

In a study of fruit flies, NIH scientists suggested that the body's immune system may play a critical role in the damage caused by aging brain disorders. The results are based on experiments in which the researchers altered the activity of Cdk5, a gene that preclinical studies have suggested is important for early brain development and may be involved in neurodegenerative diseases, such as ALS, Alzheimer's and Parkinson's disease.

2 Jan 2019

Molecular signatures reveal why women are more likely to die from glioblastoma

Scientists have discovered molecular signatures that reveal why women are more likely to develop and die from the brain cancer, glioblastoma.

2 Jan 2019

Gene News and Research

Latest Gene News and Research

Salk researchers reveal clues into early development of ASD

Researchers identify genetic risk factor for atypical heart attack in women

Cellular protein signal can be manipulated to favor bone building

USC research could lay foundation for a vaccine against tick-borne virus

Study of rare uterine sarcoma reveals clinically relevant molecular subtypes

First viable mouse model of Hirschsprung's disease developed

Study elucidates how essential amino acid in humans acts as growth signal for cells

GE Healthcare and VUMC announce partnership to enable safer, more precise cancer immunotherapies

Common food additive could cause celiac disease, review says

Research reveals factors at play in genetic incompatibility of different species

Research illuminates abilities of ADAR1 to ‘hyper-mutate’ tumor suppressor RNAs in leukemia

Bulldogs' screw tails linked to rare inherited syndrome in humans

Study follows children into adolescence to more accurately assess type 1 diabetes risk

Study: Mice lacking PARL protein display specific problems in the nervous system reminiscent of Leigh syndrome

Researchers identify genes that drive male-female brain differences, trigger initiation of puberty

Scientists cast new light on function of long-mysterious PCSK9 mutation

Study provides new insights into how genes are activated

Rockefeller scientists uncover genetic mutation responsible for tuberculosis vulnerability

Hyperactive immune system implicated in aging brain disorders

Molecular signatures reveal why women are more likely to die from glioblastoma

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