Gene News and Research

Latest Gene News and Research

Active ingredient in eye drops shows promise for treating aggressive blood cancer

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells.

19 Dec 2018

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

Potential combination therapy against rare disease of the bone marrow could improve treatment

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. Its low incidence rate is one of the reasons why effective therapies are still lacking.

19 Dec 2018

Gut microbiome plays role in immune system regulation, study finds

Scientist have long known that bacteria in the intestines, also known as the microbiome, perform a variety of useful functions for their hosts, such as breaking down dietary fiber in the digestive process and making vitamins K and B7.

19 Dec 2018

New therapy for childhood blindness shows 'very promising' results

A new therapy aimed at improving the sight of people with one of the most common forms of childhood blindness, has shown 'very promising' initial results, according to a study involving UCL researchers.

18 Dec 2018

Researchers identify link between mucus in the small airways and pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

18 Dec 2018

Study reveals mechanism behind failed remyelination in MS

Researchers have discovered that in adult stem cells, the activation of a specific transcription factor induces pathological quiescence and that this is deactivated in MS.

18 Dec 2018

New genetic testing method increases the precision of biomarker analysis

Estonian scientists have announced the invention of a genetic testing technology that allows the number of clinical biomarkers to be analyzed at the single-molecule level, which enhances the sensitivity of tests in precision medicine and will make them more affordable in future.

18 Dec 2018

Mouse study uncovers how marijuana may damage some adolescent brains

In a study of adolescent mice with a version of a gene linked to serious human mental illnesses, Johns Hopkins Medicine researchers say they have uncovered a possible explanation for how marijuana may damage the brains of some human teens.

18 Dec 2018

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

The CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or "knocking out" a gene in cancer tumors that helps the tumors develop resistance to the drugs.

18 Dec 2018

UI study leads to better understanding of signaling capacity between neurons

The fundamental process of information transfer from neuron to neuron occurs through a relay of electrical and chemical signaling at the synapse, the junction between neurons. Electrical signals, called action potentials, cause voltage-gated calcium channels on the presynaptic neuron to open.

18 Dec 2018

New $1.6 million NIH grant supports study on a gene vital to circadian rhythms

Circadian rhythms (from the Latin circa diem -- "around a day") based on the Earth's 24-hour rotation have been observed since the fourth century.

18 Dec 2018

Intraocular injection improves vision in a form of congenital retinal blindness

A new treatment for patients with a form of congenital retinal blindness has shown success in improving vision, according to results published today in Nature Medicine led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.

18 Dec 2018

Neuroscience-protein that creates borders inside the brain

Boundaries between different regions of the brain are essential for the brain to function. Research to-date has shown that molecular machineries located at the cell membrane such as cell adhesion molecules are responsible for regulating the boundary formation.

18 Dec 2018

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

In biomedical research, plant breeding, and countless other endeavors, geneticists are on the hunt for the specific genes responsible for disease susceptibility, yield, and other traits of interest.

17 Dec 2018

Researchers reveal how key transcription factor keeps the immune system in check

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end up harming healthy tissues.

17 Dec 2018

Mechanisms behind neonatal diabetes uncovered

Researchers at the University of Helsinki, Finland, have described mechanisms linking chronic cellular stress to the poor development of the insulin-producing cells.

17 Dec 2018

Study finds epigenetic differences in the brains of individuals with schizophrenia

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital has identified, for the first time, epigenetic differences between the brains of individuals with schizophrenia and those of unaffected study participants.

17 Dec 2018

Researchers uncover microRNAs involved in the control of social behavior

The recent discovery of microRNAs as key regulators of biological processes has fueled an explosion of research activity into their function in health and disease.

14 Dec 2018

Geneticists discover how sex-linked disorders arise

Researchers have discovered a regulatory gene carried on the Y chromosome that determines whether a baby will be male or female and the risk of disease.

14 Dec 2018

Gene News and Research

Latest Gene News and Research

Active ingredient in eye drops shows promise for treating aggressive blood cancer

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Potential combination therapy against rare disease of the bone marrow could improve treatment

Gut microbiome plays role in immune system regulation, study finds

New therapy for childhood blindness shows 'very promising' results

Researchers identify link between mucus in the small airways and pulmonary fibrosis

Study reveals mechanism behind failed remyelination in MS

New genetic testing method increases the precision of biomarker analysis

Mouse study uncovers how marijuana may damage some adolescent brains

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

UI study leads to better understanding of signaling capacity between neurons

New $1.6 million NIH grant supports study on a gene vital to circadian rhythms

Intraocular injection improves vision in a form of congenital retinal blindness

Neuroscience-protein that creates borders inside the brain

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

Researchers reveal how key transcription factor keeps the immune system in check

Mechanisms behind neonatal diabetes uncovered

Study finds epigenetic differences in the brains of individuals with schizophrenia

Researchers uncover microRNAs involved in the control of social behavior

Geneticists discover how sex-linked disorders arise

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