Gene News and Research

Latest Gene News and Research

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

An antibody that binds simultaneously to two distinct regions of the HER2 receptor to block the growth of cancer cells has shown promising signs of anti-tumor activity in a number of cancers including those of the gullet (esophagus), stomach and bowel.

14 Nov 2018

Study identifies potential therapeutic strategy for patients with clear cell renal cancer

Researchers have provided new insight on the mechanisms behind the development of clear cell Renal Cell Carcinoma (ccRCC), according to new findings published in eLife.

13 Nov 2018

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia

While it has long been recognized that mutated gene NPM1 plays an important role in acute myeloid leukemia, no one has determined how the normal and the mutated forms of the protein NPM1 function.

13 Nov 2018

NIH awards $3.5 million to continue development of robotic system for treating brain tumors

Researchers at Worcester Polytechnic Institute and Albany Medical College, along with corporate partners GE Global Research and Acoustic MedSystems Inc., have received a five-year, $3.5 million award from the National Institutes of Health through the National Cancer Institutes' Academic-Industrial Partnership program, to continue development of an innovative robotic system that, operating within an MRI scanner, can deliver a minimally invasive probe into the brain to destroy metastatic brain tumors with high-intensity therapeutic ultrasound under real-time guidance.

13 Nov 2018

Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health

According to new research, epigenetic changes found in the offspring exposed to maternal smoking during pregnancy or in current smokers are linked to smoking-related diseases in adulthood.

13 Nov 2018

Immunity connects gut microbiota and age-related pathologies

EPFL scientists have discovered how a dysfunction in the immune system can cause an overload of a gut bacterium. The bacterium produces excess lactic acid, which in turn triggers the production of reactive oxygen species that cause damage to cells and many age-related pathologies.

13 Nov 2018

Study shows new emerging role of osteopontin in HCV-related hepatocellular carcinoma

Hepatitis C virus (HCV) infection is the major cause of hepatocellular carcinoma (HCC) and was estimated to be responsible for 745,000 deaths in 2012.

13 Nov 2018

Study uncovers link between gut disruption and aging

A new study has shed light on how the disruption of commensal bacteria within the gut can affect the immune system and lead to age-related pathologies.

13 Nov 2018

First bifacial molecule can invade double-stranded DNA or RNA

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could provide a new platform for developing methods for the diagnosis and treatment of genetic conditions.

13 Nov 2018

Growth and spread of deadly eye tumor suppressed in cells, animals

By comparing genetic sequences in the eye tumors of children whose cancers spread with tumors that didn't spread, Johns Hopkins Medicine researchers report new evidence that a domino effect in cells is responsible for the cancer spreading.

12 Nov 2018

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Experimenting with lab-grown brain cancer cells, Johns Hopkins Medicine researchers have added to evidence that a shortage of specific tiny molecules that silence certain genes is linked to the development and growth of pediatric brain tumors known as low-grade gliomas.

12 Nov 2018

Kawasaki disease may be triggered by a combination of environmental factors

A new study has found that Kawasaki disease (KD) is not caused by one single factor but has multiple environmental triggers.

12 Nov 2018

Medical experts discuss future challenges of healthcare at HSMA’s inaugural conference

Last week The Howard de Walden Estate gathered medical experts from across the industry for a one day conference to discuss the future challenges of healthcare in the UK and globally.

12 Nov 2018

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Genetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a common feature of cardiovascular disease, according to a new study by an international team of researchers led by scientists at UC San Francisco and Washington University School of Medicine in St. Louis.

9 Nov 2018

Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility

About 1.5 billion years ago, tiny visitors came to live inside the cells that later evolved into all plant and animal life -- including humans.

9 Nov 2018

Small populations of normal T cells could modify disease severity in patients with XLP1

Human SH2D1A mutations resulting in X-linked lymphoproliferative syndrome type 1 are associated with a unique susceptibility to the Epstein-Barr virus, which may lead to fatal infectious mononucleosis.

9 Nov 2018

ChromDesign project trains budding scientists in 3D architecture of genome

How does the three-dimensional architecture of our genes affect the differentiation of cells and development of diseases? This is the question behind the European Innovation Training Network "ChromDesign- Chromatin and Design".

8 Nov 2018

Salk researchers solve genetic 'whodunnit' for cancer gene

Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, Salk Institute researchers have solved the long-standing mystery around why AMPK can both hinder and help cancer.

8 Nov 2018

Scientists move closer to gonorrhea vaccine after large-scale proteomic study

In a study of proteins historic in its scope, researchers at Oregon State University have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause the disease are so good at fending off antimicrobial drugs.

8 Nov 2018

Researchers identify epigenetic changes that increase risk of type 2 diabetes

Small chemical changes in the DNA building blocks, which may be influenceable by lifestyle factors, can reduce the amount of IGFBP2. A DIfE / DZD research team has now reported in the journal Diabetes that these epigenetic changes increase the risk of type 2 diabetes.

8 Nov 2018

Gene News and Research

Latest Gene News and Research

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

Study identifies potential therapeutic strategy for patients with clear cell renal cancer

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia

NIH awards $3.5 million to continue development of robotic system for treating brain tumors

Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health

Immunity connects gut microbiota and age-related pathologies

Study shows new emerging role of osteopontin in HCV-related hepatocellular carcinoma

Study uncovers link between gut disruption and aging

First bifacial molecule can invade double-stranded DNA or RNA

Growth and spread of deadly eye tumor suppressed in cells, animals

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Kawasaki disease may be triggered by a combination of environmental factors

Medical experts discuss future challenges of healthcare at HSMA’s inaugural conference

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility

Small populations of normal T cells could modify disease severity in patients with XLP1

ChromDesign project trains budding scientists in 3D architecture of genome

Salk researchers solve genetic 'whodunnit' for cancer gene

Scientists move closer to gonorrhea vaccine after large-scale proteomic study

Researchers identify epigenetic changes that increase risk of type 2 diabetes

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging