Gene News and Research

Latest Gene News and Research

GW study examines impact of nervous system on non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease, the accumulation of fat in the liver of people who drink little or no alcohol, affects 1 in 3 Americans. NAFLD is a significant risk factor for Type 2 diabetes, insulin resistance, and hepatic carcinoma, and incidence of the disease is increasing with the growing obesity epidemic in the United States.

8 Nov 2018

Researchers secure NIH grant to prevent heart disease in chronic kidney disease patients

Researchers at New York Institute of Technology have secured a grant for $391,041 from the National Institutes of Health that may allow for improved understanding of vascular calcification and prevent heart disease in chronic kidney disease patients.

8 Nov 2018

New, naturally low-caffeine option for tea drinkers

Tea drinkers who seek the popular beverage's soothing flavor without its explosive caffeine jolt could soon have a new, naturally low-caffeine option.

8 Nov 2018

Scientists grow 3D, beating human heart tissue

Researchers at the University Medical Center Hamburg-Eppendorf have found a way to grow human heart tissue that can serve as a model for the atria of the heart.

8 Nov 2018

Researchers discover gene signature biomarker that may predict patients' response to immune therapy

Scientists led by Dr. Daniel De Carvalho at Princess Margaret Cancer Centre have discovered a gene signature biomarker that may predict which patients will respond - or not - to immune therapy.

8 Nov 2018

Researchers find new tiny molecule that is capable of killing medulloblastoma

A new study by UT Health San Antonio researchers found that a molecule thousands of times smaller than a gene is able to kill medulloblastoma, the most common childhood brain cancer.

8 Nov 2018

CWRH/UH researcher receives grant to study role of KLF2 factor in vascular-related disorders

Transcription factors are proteins that determine whether specific genes are transcribed or not by binding to DNA. In other words, they help turn genes "on" or "off."

8 Nov 2018

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

A new study by Washington State University researchers suggests that a protein called CDK2 plays a critical role in heart damage caused by doxorubicin, a commonly used chemotherapy drug.

8 Nov 2018

New study shows promise of innovative strategy against HER2-driven lung cancers

The HER2 gene is a well-known driver of breast cancer, where changes in this gene are found in about 1-in-5 cases of the disease. HER2 also contributes to about 3 percent of lung cancers, representing about 6,500 patients per year.

8 Nov 2018

Study elucidates genetic causes of severe cardiomyopathies in children

Cardiac muscle degeneration (cardiomyopathy) is the most common cause of severe cardiac dysfunction and life-threatening cardiac arrhythmias in children. These severe disorders often lead to consideration of heart transplant. However, their actual cause - the genetic basis - has been poorly characterized.

7 Nov 2018

Promising new glioblastoma treatment could improve and extend patients' lives

Glioblastoma is a serious and incurable brain cancer. Patients receiving this diagnosis typically have 11-20 months to live. One of the main difficulties in treating this cancer is that its cells quickly build up a resistance to chemotherapy.

7 Nov 2018

UTSA research could help address genetically based challenges with male fertility

Millions of couples who have trouble conceiving may get relief from new research led by scientists at The University of Texas at San Antonio.

7 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Tracking down microRNA candidates linked to disease

What started as Ninad Oak's side project turned out into something much larger, his doctorate thesis. "The project started as my qualifying exam that I proposed at the end of my first year of graduate school," said Oak, a graduate student in molecular and human genetics in Dr. Sharon E. Plon's lab. "This was an off topic qualifying exam at the time, meaning the lab had not worked on this topic before."

7 Nov 2018

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong, in collaboration with scientists from Tsinghua University in China, The Rockefeller University, and The University of Texas MD Anderson Cancer Center in the United States, developed the first chemical inhibitors against a novel therapeutic target for treatment of acute myeloid leukemia, a fast-growing cancer of bone marrow and blood cells.

7 Nov 2018

Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

Treating pre-cancerous stem cells at an early stage could be key to preventing bowel cancer in people born with a very high risk of the disease, according to a study in mice presented at the 2018 NCRI Cancer Conference.

7 Nov 2018

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

The U.S. Department of Defense has granted the "Impact Award" to explore new therapeutic options against advanced prostate cancer - scientifically known as castration-resistant or hormone therapy resistant prostate cancer- to a multidisciplinary team of researchers made up of the Prostate Cancer Clinical Research Unit of the Spanish National Cancer Research Center, led by David Olmos, the Prostate Cancer Translational Research Group of the Vall d'Hebron Institute of Oncology, led by Joaquín Mateo, and the Genetics and Solid Tumors Laboratory of the University of Washington, led by Colin Pritchard.

7 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

The human gut is teeming with billions of beneficial bacteria. Therapies that use antibiotics often destroy most of them.

7 Nov 2018

Researchers identify pathway to resolve allergic asthma

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible for producing a cytokine that triggers a cascade of events resulting in the onset and progression of the disease.

6 Nov 2018

Gene News and Research

Latest Gene News and Research

GW study examines impact of nervous system on non-alcoholic fatty liver disease

Researchers secure NIH grant to prevent heart disease in chronic kidney disease patients

New, naturally low-caffeine option for tea drinkers

Scientists grow 3D, beating human heart tissue

Researchers discover gene signature biomarker that may predict patients' response to immune therapy

Researchers find new tiny molecule that is capable of killing medulloblastoma

CWRH/UH researcher receives grant to study role of KLF2 factor in vascular-related disorders

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

New study shows promise of innovative strategy against HER2-driven lung cancers

Study elucidates genetic causes of severe cardiomyopathies in children

Promising new glioblastoma treatment could improve and extend patients' lives

UTSA research could help address genetically based challenges with male fertility

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Tracking down microRNA candidates linked to disease

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

Scientists discover new details about UHRF1 protein

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

Researchers identify pathway to resolve allergic asthma

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