Gene News and Research

Latest Gene News and Research

New study focuses on two-way gene switches controlling gene activity

Led by ICREA research professors at the Centre for Genomic Regulation, Luciano Di Croce and Marc A. Marti-Renom, the study focused on a set of genes with what's known as bivalent promoters - two-way genetic 'control switches' that are poised either to turn on in early development and rapidly drive high levels of gene activity, or to switch off and shut down the gene completely.

20 Sep 2018

First U.S. patient treated with innovative gene therapy at Bascom Palmer Eye Institute

A Puerto Rican patient with X-linked retinitis pigmentosa (XLRP) is hoping to save his vision after an innovative gene therapy procedure at Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine.

19 Sep 2018

UNC scientists reveal new approach to prevent obesity and diabetes

Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet.

19 Sep 2018

Antioxidant in green tea helps sneak therapeutic RNAs into cells

Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss.

19 Sep 2018

DermTech completes enrollment in clinical study to assess DNA damage and reversal

DermTech, Inc., the global leader in non-invasive molecular dermatology, announced today it has completed enrollment in a clinical study to assess DNA damage induced by an excimer laser and evaluate the potential of topical agents T4 endonuclease and photolyase to reduce DNA damage induced as measured through gene expression analysis.

19 Sep 2018

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Exelixis, Inc. today announced that its partner Ipsen Biopharmaceuticals Canada Inc. received approval from Health Canada of CABOMETYX® tablets for the treatment of adults with advanced renal cell carcinoma who have received prior vascular endothelial growth factor targeted therapy.

19 Sep 2018

Study finds why some human genes are more popular with biomedical researchers

Historical bias is a key reason why biomedical researchers continue to study the same 10 percent of all human genes while ignoring many genes known to play roles in disease, according to a study publishing September 18 in the open access journal PLOS Biology, led by Thomas Stoeger and Luís Amaral of Northwestern University, and colleagues. This bias is bolstered by research funding mechanisms and social forces.

19 Sep 2018

Henry Ford Health System receives $600k grant to study genetic makeup of gliomas

Henry Ford Health System's Department of Neurosurgery was awarded a $600,000 grant by the Department of Defense to study the genetic makeup of gliomas, a type of brain cancer, in hope of identifying new therapies.

19 Sep 2018

Penn researchers find common thread linking almost all TNR expansion diseases

In a class of roughly 30 neurological disorders that includes ALS, Huntington's Disease and Fragile X Syndrome, the relevant mutant gene features sections of repeating base pair sequences known as short tandem repeats, or STRs. Healthy people have STRs of normal lengths distributed across their DNA.

19 Sep 2018

Scientists discover new molecules that work together to remove unwanted DNA

Scientists have discovered a new family of molecules that work together to precisely remove unwanted DNA during reproduction in single-celled, freshwater organisms called ciliates.

19 Sep 2018

Tweaking nuclear pores could provide new avenue to battle against cancer

If the cell nucleus is like a bank for DNA, nuclear pores are the security doors around its perimeter. Yet more security doors aren't necessarily better: some cancer cells contain a dramatic excess of nuclear pores.

19 Sep 2018

Research shows enlarged genotype-phenotype correlation for three-base pair deletion in NF1

International collaborative research led by Ludwine Messiaen, Ph.D., shows that while a three-base pair, in-frame deletion called p.Met992del in the NF1 gene has a mild phenotype for people with the genetic disorder neurofibromatosis type 1, or NF1, the mutation does cause complications.

18 Sep 2018

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

A little p63 goes a long way in embryonic development - and flaws in p63 can result in birth defects like cleft palette, fused fingers or even missing limbs.

18 Sep 2018

Scientists find the genetic code underlying limb growth

Researchers at the Ecole Polytechnique Fédérale de Lausanne have discovered the gene code that sets the pace and order of fetal development.

18 Sep 2018

KAIST researchers develop heart-targeting drug delivery technology using tannin acid

Typical methods of drug delivery to the heart require surgical procedures involving incisions in the chest wall and bones.

18 Sep 2018

Key signaling molecule that helps stem cells make healthy bone declines as we age

With age, expression of a small molecule that can silence others goes way up while a key signaling molecule that helps stem cells make healthy bone goes down, scientists report.

18 Sep 2018

Researchers identify key step in how plant cells respond to pathogens

Just like humans, plants have an immune system that helps them fight off infections. Plant immunity has some important differences: they don't make antibodies and can't fight off the same bug more quickly months or years later.

18 Sep 2018

Brigham Genomic Medicine program unravels 30 medical mysteries

A table in a recently published paper tells the story of 30 families who have, sometimes after years of searching, finally received an answer about the condition that has plagued one or more family members.

18 Sep 2018

Researchers use CRISPR to identify gene that helps cells resist flavivirus infection

UT Southwestern researchers today report the first use of CRISPR genome-wide screening to identify a gene that helps cells resist flavivirus infection. That nasty class of pathogens includes West Nile virus, dengue fever, Zika virus, and yellow fever.

18 Sep 2018

Machine learning program could distinguish between two lung cancer types

A new computer program can analyze images of patients' lung tumors, specify cancer types, and even identify altered genes driving abnormal cell growth, a new study shows.

17 Sep 2018

Gene News and Research

Latest Gene News and Research

New study focuses on two-way gene switches controlling gene activity

First U.S. patient treated with innovative gene therapy at Bascom Palmer Eye Institute

UNC scientists reveal new approach to prevent obesity and diabetes

Antioxidant in green tea helps sneak therapeutic RNAs into cells

DermTech completes enrollment in clinical study to assess DNA damage and reversal

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Study finds why some human genes are more popular with biomedical researchers

Henry Ford Health System receives $600k grant to study genetic makeup of gliomas

Penn researchers find common thread linking almost all TNR expansion diseases

Scientists discover new molecules that work together to remove unwanted DNA

Tweaking nuclear pores could provide new avenue to battle against cancer

Research shows enlarged genotype-phenotype correlation for three-base pair deletion in NF1

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

Scientists find the genetic code underlying limb growth

KAIST researchers develop heart-targeting drug delivery technology using tannin acid

Key signaling molecule that helps stem cells make healthy bone declines as we age

Researchers identify key step in how plant cells respond to pathogens

Brigham Genomic Medicine program unravels 30 medical mysteries

Researchers use CRISPR to identify gene that helps cells resist flavivirus infection

Machine learning program could distinguish between two lung cancer types

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

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