Gene News and Research

Latest Gene News and Research

Differences in mitochondrial DNA determine severity of heart disease caused by nDNA mutation

Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation.

12 Sep 2018

Researchers design new medicine to treat highly aggressive pancreatic cancer

A treatment for highly aggressive and commonly fatal pancreatic cancer is being developed, reports a University of Houston researcher who has designed a new medicine that can inhibit two of the major pathways of the deadly disease.

12 Sep 2018

Prenatal cannabinoid use can cause behavioral and neuronal deficits in male offspring

Taking cannabinoids during pregnancy can cause behavioral and neuronal deficits in adult male offspring, while females remain unaffected, says new research published in eLife.

12 Sep 2018

Discovery of unusual biosynthetic pathways could aid in the search for new natural products

Bacteria are master engineers of small, biologically useful molecules. A new study in Nature Communications has revealed one of the tricks of this microbial trade: synthesizing and then later inserting a nitrogen-nitrogen bond, like a prefabricated part, into a larger molecule.

12 Sep 2018

Inhaled form of high blood pressure drug has potential to treat anxiety, pain

An inhaled form of a high blood pressure medication has potential to treat certain types of anxiety as well as pain, according to a new study by the Centre for Addiction and Mental Health.

11 Sep 2018

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

Scientists with the Virginia Tech Carilion Research Institute say a gene involved in the body's circadian rhythms is a potential target for therapies to help patients with a deadly form of brain cancer known as glioblastoma.

11 Sep 2018

Eastenders actress supports awareness campaign on importance of eye tests

Leading eye research charity Fight for Sight has found that nearly three in ten British adults don’t follow the NHS recommendation to have an eye test every two years, and that the majority of this group (74%) say that it’s either because they can’t afford it or because they ‘can see fine’.

11 Sep 2018

Synergism between HOXB13 and CIP2A genes predisposes men to get prostate cancer

A research team at the University of Turku in Finland discovered a link between the interplay of certain simultaneously occurring genetic changes in the HOXB13 and CIP2A genes, aggressiveness of prostate cancer, high risk of developing the disease, and poorer survival rates of patients.

11 Sep 2018

Researchers unravel how Zika virus manipulates the human immune system

Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune cells.

11 Sep 2018

BAP1 protein serves as tumor suppressor gene in kidney, eye, bile duct and mesothelioma cancers

Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research.

10 Sep 2018

Mouse study suggests new therapeutic approach to treat heart failure

A heart attack triggers an acute inflammatory response, followed by resolution of inflammation and wound healing. A severe heart attack, however, can cause chronic and sustained inflammation that leads to heart failure and death.

10 Sep 2018

New framework combines three existing methods to find cancer cell mutations

Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a new method may offer more complete, comprehensive results.

10 Sep 2018

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

UC San Francisco researchers have discovered how a mutation in a gene regulator called the TERT promoter -- the third most common mutation among all human cancers and the most common mutation in the deadly brain cancer glioblastoma -- confers "immortality" on tumor cells, enabling the unchecked cell division that powers their aggressive growth.

10 Sep 2018

Male and female brains are affected differently by repeated binge drinking

Gene expression in an area of the brain linked to addiction is affected differently by repeated binge drinking in males and females, finds a new study published today in Frontiers in Genetics.

10 Sep 2018

Individualized therapies targeting specific features show promise in transforming cancer treatment

Individualized therapies that target the specific genetic features of tumors have the potential to transform cancer diagnosis, treatment and care.

10 Sep 2018

Superbugs often move between humans and animals

The MRSA staphylococcus is an example of a pathogen, the likes of which are often called superbugs. These are resistant to most antibiotics and can cause serious infections.

7 Sep 2018

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Exelixis, Inc. today announced that the National Comprehensive Cancer Network updated its Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets.

7 Sep 2018

A joint effort to provide new insights into how gene activity drives cartilage development

Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem Cell laboratory of Denis Evseenko, MD, PhD, collaborated with colleagues at several institutions to provide new insights into how gene activity drives the development of cartilage.

7 Sep 2018

Mimicking Human Brain Development Using Organoids

Dr. Paul Tesar from the Tesar Laboratory at Case Western University, Ohio, discusses the importance of organoids in biological research and the development of organoids which are capable of simulating the early stages of human myelin.

7 Sep 2018

Researchers develop rapid, cost-effective method to create human cortical organoids

Writing in the current online issue of the journal Stem Cells and Development, researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.

7 Sep 2018

Gene News and Research

Latest Gene News and Research

Differences in mitochondrial DNA determine severity of heart disease caused by nDNA mutation

Researchers design new medicine to treat highly aggressive pancreatic cancer

Prenatal cannabinoid use can cause behavioral and neuronal deficits in male offspring

Discovery of unusual biosynthetic pathways could aid in the search for new natural products

Inhaled form of high blood pressure drug has potential to treat anxiety, pain

Gene involved in circadian rhythms can be potential target for glioblastoma treatment

Eastenders actress supports awareness campaign on importance of eye tests

Synergism between HOXB13 and CIP2A genes predisposes men to get prostate cancer

Researchers unravel how Zika virus manipulates the human immune system

BAP1 protein serves as tumor suppressor gene in kidney, eye, bile duct and mesothelioma cancers

Mouse study suggests new therapeutic approach to treat heart failure

New framework combines three existing methods to find cancer cell mutations

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

Male and female brains are affected differently by repeated binge drinking

Individualized therapies targeting specific features show promise in transforming cancer treatment

Superbugs often move between humans and animals

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

A joint effort to provide new insights into how gene activity drives cartilage development

Mimicking Human Brain Development Using Organoids

Researchers develop rapid, cost-effective method to create human cortical organoids

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging