Gene News and Research

Latest Gene News and Research

Diet-induced obesity synchronizes opposing liver fat metabolic processes in mice

Mice fed a fattening diet develop new liver circadian rhythms that impact the way fat is accumulated and simultaneously burned, according to a new study published in Cell by researchers in the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2018

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending approval of Tafinlar® in combination with Mekinist® for the adjuvant treatment of adult patients with stage III melanoma with a BRAF V600 mutation, following complete resection.

27 Jul 2018

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Committee for Medicinal Products for Human Use has adopted a Positive Opinion recommending marketing authorization of patisiran for the treatment of hereditary transthyretin-mediated amyloidosis in adults with stage 1 or stage 2 polyneuropathy.

27 Jul 2018

Researchers discover novel antibiotic from leaf of common weed

Researchers working on an SNSF project have discovered novel, antibiotically active chemical substances in a previously rarely explored site: the leaf of a common field weed.

27 Jul 2018

Newer version of ALS drug may effectively treat inherited form of the disease

NIH-funded researchers delayed signs of amyotrophic lateral sclerosis in rodents by injecting them with a second-generation drug designed to silence the gene, superoxide dismutase 1.

27 Jul 2018

Researchers identify genes linked to childhood nephrotic syndrome

Childhood nephrotic syndrome is the most frequently occurring chronic kidney disease among children. A Japanese research team has identified a group of genes that are strongly related to the development of childhood nephrotic syndrome.

27 Jul 2018

Researchers discover new protein that controls level of inflammation-inducing molecule

One of the major therapeutic targets for inflammatory diseases is the inflammation-inducing molecule TNF. However, excess levels of TNF cause side effects and can lead to diseases.

27 Jul 2018

Nucleic acid nanoparticles found to have varying immune responses

An extensive experiment testing the immune effects of a broad group of lab-designed nucleic acid nanoparticles did not find a strong, uniform immune response, as had been predicted.

27 Jul 2018

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

Researchers have helped solve a decades-old mystery about which mutations are responsible for an inherited bone marrow disorder.

27 Jul 2018

Scientists take important step to understand mechanisms that cause Huntington's disease

The neuroscientist Dr David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease.

27 Jul 2018

Study shares public views of using gene editing to change unborn baby’s genetic makeup

A majority of Americans support the idea of using gene editing with the goal of delivering direct health benefits for babies.

27 Jul 2018

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

An international team of scientists, including researchers from Baylor College of Medicine, has discovered mutations of gene IRF2BPL that are associated with a previously undiagnosed neurological disorder in seven unrelated individuals.

27 Jul 2018

Most Americans skeptical about gene editing

A new survey from Pew Research Center has found that nearly half of the surveyed Americans believe that in the coming 50 years, nearly all genetic birth defects could be eliminated due to advances in gene editing.

26 Jul 2018

New mouse model shows great promise for Rett syndrome research

In an article released today from Jeannie T. Lee, MD PhD of Massachusetts General Hospital, there is hope on the horizon for future research specific to Rett syndrome, a rare childhood neurodevelopmental disorder.

26 Jul 2018

Scientists discover gene that predicts arthritis severity

Scientists have discovered a new gene that is associated with disease severity in rheumatoid arthritis. HIP1 produces an inflammatory molecule which drives RA.

26 Jul 2018

Researchers find distinct microbiomes in airway, gastrointestinal systems of children with chronic cough

Different respiratory diseases associated with chronic cough create distinct microbial imbalances in the lower airways of children, according to a study led by researchers at NYU School of Medicine.

26 Jul 2018

Scientists uncover new strategy to kill tumors without harming healthy cells

Scientists at Scripps Research have uncovered a new strategy to kill tumors, including some triple-negative breast cancers, without harming healthy cells, a discovery that could lead to more ways to treat tumors while reducing side effects.

26 Jul 2018

Study reveals key role of actin cytoskeletal dynamics in supporting immune cell function

In order to move, a body needs a strong scaffold. This is not only true on a macroscopic level, where animals rely on skeletons to support their muscles.

26 Jul 2018

Anti-cancer gene may switch side and promote cancer growth, shows study

It doesn't often happen that army generals switch sides in the middle of a war, but when cancer's attack is underway, it may even cause a gene that acts as the body's master defender to change allegiance.

26 Jul 2018

Study observes how nanoplastics cause damage to DNA and cell membranes in mussels

Plastic pollution is a worldwide environmental problem which worsens when this material degrades into smaller-sized particles such as microplastics and nanoplastics, the latter capable of penetrating into an organism's cells.

26 Jul 2018

Gene News and Research

Latest Gene News and Research

Diet-induced obesity synchronizes opposing liver fat metabolic processes in mice

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Researchers discover novel antibiotic from leaf of common weed

Newer version of ALS drug may effectively treat inherited form of the disease

Researchers identify genes linked to childhood nephrotic syndrome

Researchers discover new protein that controls level of inflammation-inducing molecule

Nucleic acid nanoparticles found to have varying immune responses

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

Scientists take important step to understand mechanisms that cause Huntington's disease

Study shares public views of using gene editing to change unborn baby’s genetic makeup

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

Most Americans skeptical about gene editing

New mouse model shows great promise for Rett syndrome research

Scientists discover gene that predicts arthritis severity

Researchers find distinct microbiomes in airway, gastrointestinal systems of children with chronic cough

Scientists uncover new strategy to kill tumors without harming healthy cells

Study reveals key role of actin cytoskeletal dynamics in supporting immune cell function

Anti-cancer gene may switch side and promote cancer growth, shows study

Study observes how nanoplastics cause damage to DNA and cell membranes in mussels

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

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