Gene News and Research

Latest Gene News and Research

Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing

Single-cell sequencing technologies are filling in fine details in the catalog of life. Researchers at the University of Connecticut Health Center and The Jackson Laboratory have identified 40 subtypes of retinal ganglion cells along with the genetic markers and transcription factors that differentiate them.

19 Jul 2018

Scientists identify melanoma biomarkers that could help tailor immunotherapy treatments

Scientists at Dana-Farber/Brigham and Women's Cancer Center have identified biomarkers in melanoma that could help tailor immunotherapy treatments to maximize the benefits for patients while reducing the likelihood of severe side effects.

19 Jul 2018

Research uncovers new target for therapeutic intervention in breast cancer

Research led by Suresh Alahari, PhD, Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has shown for the first time that a tiny piece of RNA deregulates energy metabolism, an emerging hallmark of cancer. The finding identifies a new target for therapeutic intervention in breast cancer.

18 Jul 2018

Study calls for new gold standard in research to treat non-alcoholic steatohepatitis

A new study by scientists from the Vrije Universiteit Brussel calls for a new gold standard in research to treat non-alcoholic steatohepatitis, an obesity-linked chronic liver disease impacting millions of people of all ages worldwide, which can progress to liver cancer if untreated, creating a massive strain on an already overburdened healthcare system.

18 Jul 2018

Single genetic change in gut bacteria can lead to obesity

A new study has shown that a single genetic change in a bacterium of the gut microbiome can lead to metabolic diseases such as obesity.

18 Jul 2018

Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice, according to a study in the journal eLife.

18 Jul 2018

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Osaka University-led study shows how a high-fat diet and systemic inflammation contribute to prostate cancer progression

18 Jul 2018

Maintaining high levels of vinculin confers heart health benefits to fruit flies

Our cells tend to lose their shape as we grow older, contributing to many of the effects we experience as aging. This poses particular problems for the heart, where aging can disrupt the protein network within muscle cells that move blood around the body.

18 Jul 2018

Researchers identify key protein involved in irregular brain cell activity

In a new study in mice, researchers have identified a key protein involved in the irregular brain cell activity seen in autism spectrum disorders and epilepsy. The protein, p53, is well-known in cancer biology as a tumor suppressor.

17 Jul 2018

Inflection Biosciences' dual mechanism inhibitor shows promise as treatment for CLL

Inflection Biosciences Ltd, a private company developing innovative therapeutics for cancer, today announced the publication of preclinical data showing the company's dual mechanism PIM/PI3 kinase inhibitor IBL-202 has promise as a treatment for chronic lymphocytic leukemia.

17 Jul 2018

Researchers develop machine learning method to predict unknown gene functions of microbes

An international team led by computational biologist Fran Supek at IRB Barcelona develop a machine learning method to predict unknown gene functions of microbes.

17 Jul 2018

Study identifies new genes linked to heart function and development

A new study from an international research team, led by Dr Yalda Jamshidi at St George's, University of London, has identified new genes associated with heart function and development.

17 Jul 2018

Staggering prices slow insurers’ coverage of CAR-T cancer therapy

Patients whose blood cancers have failed to respond to repeated rounds of chemotherapy may be candidates for a new type of gene therapy that could send their cancers into remission for years.

17 Jul 2018

Study findings highlight importance of early detection of SMA through newborn screening

Spinal muscular atrophy is a genetic disease that affects motor neurons in the spinal cord, resulting in muscle atrophy and widespread weakness that eventually impair swallowing and breathing.

17 Jul 2018

New machine learning framework predicts effects of genetic mutations in ‘dark matter’ regions

A new machine learning framework, dubbed ExPecto, can predict the effects of genetic mutations in the so-called "dark matter" regions of the human genome.

17 Jul 2018

Researchers map family trees of cancer cells to understand how AML responds to new drug

For the first time, a team of international researchers have mapped the family trees of cancer cells in acute myeloid leukemia to understand how this blood cancer responds to a new drug, enasidenib.

17 Jul 2018

NeuroTrauma Sciences and Henry Ford join hands to advance exosome technology

NeuroTrauma Sciences, LLC, a biopharmaceutical company, and Henry Ford Health System, a non-profit organization, today announce that a newly-formed subsidiary of NTS has entered into multi-year Sponsored Research and License Agreements.

16 Jul 2018

Study highlights potential of fetal gene therapy to prevent lethal neurodegenerative disease

A fatal neurodegenerative condition known as Gaucher disease can be prevented in mice following fetal gene therapy, finds a new study led by UCL, the KK Women's and Children's Hospital and National University Health System in Singapore.

16 Jul 2018

CRISPR/Cas9 gene editing can cause greater genetic damage than previously thought

Scientists at the Wellcome Sanger Institute have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies using CRISPR/Cas9 in the future as the unexpected damage could lead to dangerous changes in some cells.

16 Jul 2018

Researchers solve mystery of final blood group system

Ever since the blood type was discovered in 1962, no one has been able to explain why some people become Xga positive while others are Xga negative.

16 Jul 2018

Gene News and Research

Latest Gene News and Research

Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing

Scientists identify melanoma biomarkers that could help tailor immunotherapy treatments

Research uncovers new target for therapeutic intervention in breast cancer

Study calls for new gold standard in research to treat non-alcoholic steatohepatitis

Single genetic change in gut bacteria can lead to obesity

Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Maintaining high levels of vinculin confers heart health benefits to fruit flies

Researchers identify key protein involved in irregular brain cell activity

Inflection Biosciences' dual mechanism inhibitor shows promise as treatment for CLL

Researchers develop machine learning method to predict unknown gene functions of microbes

Study identifies new genes linked to heart function and development

Staggering prices slow insurers’ coverage of CAR-T cancer therapy

Study findings highlight importance of early detection of SMA through newborn screening

New machine learning framework predicts effects of genetic mutations in ‘dark matter’ regions

Researchers map family trees of cancer cells to understand how AML responds to new drug

NeuroTrauma Sciences and Henry Ford join hands to advance exosome technology

Study highlights potential of fetal gene therapy to prevent lethal neurodegenerative disease

CRISPR/Cas9 gene editing can cause greater genetic damage than previously thought

Researchers solve mystery of final blood group system

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging