Gene News and Research

Latest Gene News and Research

Researchers develop new methods for studying evolution of cancer treatment resistance

New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center.

3 Jul 2018

Researchers identify molecular mechanism leading to cortical malformation from brain-only mutations

Focal malformations of cortical development are a heterogeneous group of brain cortical abnormalities.

2 Jul 2018

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

A new Tel Aviv University study suggests there is hope of treating certain inborn congenital metabolic diseases -- a hope found in green tea and in red wine.

2 Jul 2018

New biomarker paves way for personalized bladder cancer treatments

Researchers have identified a potential new target for the treatment of a particularly aggressive form of bladder cancer, in the form of microRNA.

2 Jul 2018

Cilia appears to play key role in formation of melanoma

Most cells in the human body have a cilium, a slender cell protuberance that picks up signals from the cell's external environment.

2 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Streamlining and translating basic science discoveries into the clinic

To make sure that good ideas to enhance healthcare are not lost due to a lack of resources, a growing number of centers at Penn Medicine organize forums to pitch ideas to improve medical devices and technology, hold annual competitions to fund studies to improve patient care while keeping costs down, and sponsor seed grants for programs focused on patients who need individualized tailoring of their treatment.

2 Jul 2018

Researchers discover gene that plays role in regulating body's immune response to infection

Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease.

2 Jul 2018

Individuals may react differently to environmental chemicals based upon genetic profile

Why do individuals respond differently to the same environment? Researchers from North Carolina State University and Oregon State University have pinpointed a genetic difference in zebrafish tied to differing responses to the same environmental chemical.

30 Jun 2018

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

The California Institute for Regenerative Medicine board has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients that will genetically engineer their stem cells to better tolerate chemotherapy's side effects, allowing them to receive higher doses of the therapy.

30 Jun 2018

Study: Administration of endocrine disruptor causes epigenetic changes in pregnant sow's DNA

The public debate on endocrine disrupting chemicals- exogenous substances that have the same or similar effects as endogenous hormones - has been going on for some time.

30 Jun 2018

Research shows why new cancer therapies fail to work on some patients

University of Otago research provides insights into an underlying mechanism that could explain why new cancer therapies to help treat metastatic melanoma do not always work on patients, paving the way for predicting which patients will benefit from certain drugs.

30 Jun 2018

Glucose-based dietary supplement increases muscle-force in Duchenne muscular dystrophy mouse

A dietary supplement derived from glucose increases muscle-force production in the Duchenne muscular dystrophy mouse model by 50% in ten days, according to a study conducted by researchers from Université Laval's Faculty of Medicine and Centre hospitalier universitaire de Québec Research Centre-Université Laval.

30 Jun 2018

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

James McNew's and Michael Stern's biochemical hunt for the root cause of a rare, paralyzing genetic disorder is a 10-year quest that's taken an unexpected turn toward everyday killers such as Alzheimer's disease, cancer and aging.

30 Jun 2018

Enzyme TLK2 could serve as potential therapies for breast cancer, brain condition

In recent years, researchers have focussed on the enzyme TLK2 suspecting it of playing a main role in several diseases.

30 Jun 2018

Lamin proteins organize a cell's genetic material from the sidelines

A tremendous amount of genetic material must be packed into the nucleus of every cell--a tiny compartment.

29 Jun 2018

Researchers focus on delivery of insulin in pill form

One mother vividly remembers her three-and-a-half-year-old son's pleas when he received insulin injections several times each day. "He would beg and plead, 'Don't do it Momma!'" she recalls.

29 Jun 2018

Computational biological models help uncover wealth of knowledge about atherosclerosis

Researchers have identified a new gene-activation pathway caused by lipids associated with coronary artery disease, a finding that could help identify new directions in research and drug development. The study was published in June in Nature Communications.

29 Jun 2018

Only one of 21 genes in BrS genetic test found to be associated with Brugada Syndrome

Clinical laboratories often rely on medical articles and public information on gene disease associations in determining the genes to include on genetic testing panels for specific conditions or the specific results to return to patients.

29 Jun 2018

Genes associated with autism interact to modulate variable symptoms of disease

Genes located in a large chromosomal aberration associated with autism interact with each other to modulate the variable symptoms of the disease, according to new research.

29 Jun 2018

Gene News and Research

Latest Gene News and Research

Researchers develop new methods for studying evolution of cancer treatment resistance

Researchers identify molecular mechanism leading to cortical malformation from brain-only mutations

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

New biomarker paves way for personalized bladder cancer treatments

Cilia appears to play key role in formation of melanoma

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Streamlining and translating basic science discoveries into the clinic

Researchers discover gene that plays role in regulating body's immune response to infection

Individuals may react differently to environmental chemicals based upon genetic profile

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

Study: Administration of endocrine disruptor causes epigenetic changes in pregnant sow's DNA

Research shows why new cancer therapies fail to work on some patients

Glucose-based dietary supplement increases muscle-force in Duchenne muscular dystrophy mouse

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

Enzyme TLK2 could serve as potential therapies for breast cancer, brain condition

Lamin proteins organize a cell's genetic material from the sidelines

Researchers focus on delivery of insulin in pill form

Computational biological models help uncover wealth of knowledge about atherosclerosis

Only one of 21 genes in BrS genetic test found to be associated with Brugada Syndrome

Genes associated with autism interact to modulate variable symptoms of disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging