Gene News and Research

Latest Gene News and Research

UTSA research could help address genetically based challenges with male fertility

Millions of couples who have trouble conceiving may get relief from new research led by scientists at The University of Texas at San Antonio.

7 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Tracking down microRNA candidates linked to disease

What started as Ninad Oak's side project turned out into something much larger, his doctorate thesis. "The project started as my qualifying exam that I proposed at the end of my first year of graduate school," said Oak, a graduate student in molecular and human genetics in Dr. Sharon E. Plon's lab. "This was an off topic qualifying exam at the time, meaning the lab had not worked on this topic before."

7 Nov 2018

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong, in collaboration with scientists from Tsinghua University in China, The Rockefeller University, and The University of Texas MD Anderson Cancer Center in the United States, developed the first chemical inhibitors against a novel therapeutic target for treatment of acute myeloid leukemia, a fast-growing cancer of bone marrow and blood cells.

7 Nov 2018

Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

Treating pre-cancerous stem cells at an early stage could be key to preventing bowel cancer in people born with a very high risk of the disease, according to a study in mice presented at the 2018 NCRI Cancer Conference.

7 Nov 2018

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

The U.S. Department of Defense has granted the "Impact Award" to explore new therapeutic options against advanced prostate cancer - scientifically known as castration-resistant or hormone therapy resistant prostate cancer- to a multidisciplinary team of researchers made up of the Prostate Cancer Clinical Research Unit of the Spanish National Cancer Research Center, led by David Olmos, the Prostate Cancer Translational Research Group of the Vall d'Hebron Institute of Oncology, led by Joaquín Mateo, and the Genetics and Solid Tumors Laboratory of the University of Washington, led by Colin Pritchard.

7 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

The human gut is teeming with billions of beneficial bacteria. Therapies that use antibiotics often destroy most of them.

7 Nov 2018

Researchers identify pathway to resolve allergic asthma

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible for producing a cytokine that triggers a cascade of events resulting in the onset and progression of the disease.

6 Nov 2018

Geneticists decipher new gene responsible for rare form of hair loss

Hypotrichosis simplex leads to progressive hair loss already in childhood. A team of researchers led by human geneticists at the University Hospital of Bonn has now deciphered a new gene that is responsible for this rare form of hair loss.

6 Nov 2018

Dietary restriction could help prevent age-related decline in integrity of human gut

Flies eating a Spartan diet are protected from leaky gut and the systemic inflammation associated with it as they age. Conversely, flies on a rich Atkins-like diet are more prone to developing intestinal permeability, a condition linked to a variety of human conditions including inflammatory bowel disease.

5 Nov 2018

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with ALK-positive metastatic non-small cell lung cancer whose disease has progressed on crizotinib and at least one other ALK inhibitor for metastatic disease; or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy for metastatic disease.

5 Nov 2018

TGen and City of Hope announce letter of intent to develop new cell therapy manufacturing facility

City of Hope, a world-renowned independent cancer research and treatment center, and its affiliate, Translational Genomics Research Institute, have announced a letter of intent to develop a state-of-the-art cell therapy manufacturing facility in the Phoenix Metropolitan Area, a move that would improve the speed at which stem cell research and cancer treatment is delivered.

5 Nov 2018

Genetics can be used to predict schizophrenic patient's response to antipsychotic drugs

Genetics can be used to predict a patient's response to antipsychotic drug treatment for schizophrenia, according to a recent study by investigators at The Feinstein Institute for Medical Research. The findings were published online today in the American Journal of Psychiatry.

5 Nov 2018

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

VTT and Dyadic International, Inc., today announced that VTT scientists will present the excellent results in their collaboration over the past two years at two international conferences: AAPS PharmSci on November 7th in Washington DC and PEGS Europe on November 14th in Lisbon.

5 Nov 2018

Researchers identify genetic variation that may influence severity of CTE disease

Researchers have identified a genetic variation that may influence chronic traumatic encephalopathy disease severity.

5 Nov 2018

Horizon Discovery collaborates with Biocartis to offer reference standards for new Idylla MSI assay

Horizon Discovery Group plc, a global leader in gene editing and gene modulation technologies, today announces that it has developed a set of precisely defined cell line-derived reference standards to support Biocartis’ recently launched Idylla™ microsatellite instability Assay.

From Revvity 5 Nov 2018

PPM1D gene confers a survival advantage to stem cells after chemotherapy

Chemotherapy has been associated with increased risk of leukemia years after the treatment, but what leads to that association is not clear.

2 Nov 2018

Illumina signs agreement to acquire Pacific Biosciences

Illumina, Inc. and Pacific Biosciences today announced they have signed an agreement for Illumina to acquire Pacific Biosciences at a price of $8.00 per Pacific Biosciences share in an all-cash transaction.

2 Nov 2018

TGen, City of Hope to develop cell therapy manufacturing facility in Phoenix

City of Hope, a world-renowned independent cancer research and treatment center, and its affiliate, Translational Genomics Research Institute (TGen), have announced a letter of intent to develop a state-of-the-art cell therapy manufacturing facility in the Phoenix Metropolitan Area, a move that would improve the speed at which stem cell research and cancer treatment is delivered.

2 Nov 2018

Gene News and Research

Latest Gene News and Research

UTSA research could help address genetically based challenges with male fertility

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Tracking down microRNA candidates linked to disease

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

Scientists discover new details about UHRF1 protein

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

Researchers identify pathway to resolve allergic asthma

Geneticists decipher new gene responsible for rare form of hair loss

Dietary restriction could help prevent age-related decline in integrity of human gut

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

TGen and City of Hope announce letter of intent to develop new cell therapy manufacturing facility

Genetics can be used to predict schizophrenic patient's response to antipsychotic drugs

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

Researchers identify genetic variation that may influence severity of CTE disease

Horizon Discovery collaborates with Biocartis to offer reference standards for new Idylla MSI assay

PPM1D gene confers a survival advantage to stem cells after chemotherapy

Illumina signs agreement to acquire Pacific Biosciences

TGen, City of Hope to develop cell therapy manufacturing facility in Phoenix

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research