Gene News and Research

Latest Gene News and Research

Selectively deleting stem cell factor promotes recovery after TBI in mice

UT Southwestern molecular biologists today report the unexpected finding that selectively deleting a stem cell transcription factor in adult mice promotes recovery after traumatic brain injury (TBI).

17 Nov 2017

Specially tailored, ultrafast light pulses can trigger neurons to fire in different patterns

Specially tailored, ultrafast pulses of light can trigger neurons to fire and could one day help patients with light-sensitive circadian or mood problems, according to a new study in mice at the University of Illinois.

17 Nov 2017

Researchers identify possible genetic basis for coronary artery disease

The buildup of plaque in the heart's arteries is an unfortunate part of aging. But by studying the genetic makeup of people who maintain clear arteries into old age, researchers led by UNC's Jonathan Schisler, PhD, have identified a possible genetic basis for coronary artery disease (CAD), as well as potential new opportunities to prevent it.

17 Nov 2017

Brain astrocytes could play key role in pathogenesis of Alzheimer's disease

Astrocytes, the supporting cells of the brain, could play a significant role in the pathogenesis of Alzheimer's disease (AD), according to a new study from the University of Eastern Finland. This is the first time researchers discovered a direct association between astrocytes and AD. Published in Stem Cell Reports, the study investigated the brain cell function of familial AD patients by using stem cell technologies.

17 Nov 2017

New model to test effectiveness of existing and potential CF therapies

UNC School of Medicine researchers have developed a new laboratory model of the infection- and inflammation-plagued airways of cystic fibrosis (CF) patients.

17 Nov 2017

Research suggests new ways to mitigate impact of mistreatment at early age

Everyone has challenges of one kind or another. But research shows that mistreatment at an early age can have long-lasting and life-altering repercussions that could be passed to future generations.

17 Nov 2017

FDA approves new drug to treat bleeding in hemophilia A patients

The U.S. Food and Drug Administration today approved Hemlibra (emicizumab-kxwh) to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients with hemophilia A who have developed antibodies called Factor VIII (FVIII) inhibitors.

17 Nov 2017

Scientists unveil pathology underlying optic nerve hypoplasia in children

Scientists at the Virginia Tech Carilion Research Institute (VTCRI) have revealed the pathology of cells and structures stricken by optic nerve hypoplasia, a leading cause of childhood blindness in developed nations.

16 Nov 2017

CRISPR shows potential to reduce diseases spread by mosquitoes

Research at the University of California, Riverside, have shown that it is possible for transgenic mosquitos to stably express the Cas9 enzyme in their germline. Cas9 addition will allow the utilization of the CRISPR gene editing tool to carry out efficient and highly targeted changes to the DNA of the mosquitoes.

16 Nov 2017

New research shows how a gene can fuel obesity in mice

Obesity is often attributed to a simple equation: People are eating too much and exercising too little. But evidence is growing that at least some of the weight gain that plagues modern humans is predetermined.

16 Nov 2017

Aging tests disagree with one another

Whether it's an on-line quiz, a $300 chromosome test or an $800 blood panel, a lot of people seem to be interested in whether they're aging faster or slower than their chronological age would suggest.

16 Nov 2017

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

A new study focused on describing genetic variations within a primary tumor, differences between the primary and a metastatic branch of that tumor, and additional diversity found in tumor DNA in the blood stream could help physicians make better treatment choices for patients with gastric and esophageal adenocarcinoma.

15 Nov 2017

Study identifies molecular pathway critical to development of fibrosis

A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis - scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.

15 Nov 2017

Researchers discover new way to target cancer without destroying healthy T-cells

A unique approach to targeting the abnormal T-cells that cause T-cell lymphomas could offer hope to patients with the aggressive and difficult-to-treat family of cancers, finds a study involving researchers from Cardiff University.

15 Nov 2017

Researchers test new vaccination strategy against HIV-related SIV in monkeys

According to the WHO, there are currently more than 36 million people infected with the human immunodeficiency virus (HIV) and a further 2.4 million become infected every year.

15 Nov 2017

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate to all those different cell fates.

15 Nov 2017

Study: People with non-O blood types have elevated risk of heart attack during high air pollution periods

Individuals who have A, B, or AB blood types have an elevated risk of having a heart attack during periods of significant air pollution, compared to those with the O blood type, according to new research from the Intermountain Medical Center Heart Institute and Brigham Young University.

15 Nov 2017

Tulane professor wins Department of Defense grant for research into arteriovenous malformations

Tulane University's Stryder Meadows, a cell and molecular biology professor, received a $1.7 million grant from the Department of Defense to study how arteriovenous malformations (AVM), which are defects in arteries, veins and capillaries, form Hereditary Hemorrhagic Telangiectasia (HHT), a genetic disorder that affects about 1 in 5,000 people.

14 Nov 2017

Nanoparticles carrying CRISPR gene editing tools for genetic modifications

Researchers from MIT have now developed nanoparticles that could carry CRISPR genetic editing systems deep within the cells and perform their functions on the DNA. The paper was published in the November issue of Nature Biotechnology.

14 Nov 2017

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs.

14 Nov 2017

Gene News and Research

Latest Gene News and Research

Selectively deleting stem cell factor promotes recovery after TBI in mice

Specially tailored, ultrafast light pulses can trigger neurons to fire in different patterns

Researchers identify possible genetic basis for coronary artery disease

Brain astrocytes could play key role in pathogenesis of Alzheimer's disease

New model to test effectiveness of existing and potential CF therapies

Research suggests new ways to mitigate impact of mistreatment at early age

FDA approves new drug to treat bleeding in hemophilia A patients

Scientists unveil pathology underlying optic nerve hypoplasia in children

CRISPR shows potential to reduce diseases spread by mosquitoes

New research shows how a gene can fuel obesity in mice

Aging tests disagree with one another

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

Study identifies molecular pathway critical to development of fibrosis

Researchers discover new way to target cancer without destroying healthy T-cells

Researchers test new vaccination strategy against HIV-related SIV in monkeys

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

Study: People with non-O blood types have elevated risk of heart attack during high air pollution periods

Tulane professor wins Department of Defense grant for research into arteriovenous malformations

Nanoparticles carrying CRISPR gene editing tools for genetic modifications

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging