Gene News and Research

Latest Gene News and Research

Scientists use haploid stem cells to create an atlas of the human genome

Researchers have used a sophisticated gene-editing technology to create a new type of embryonic stem cell and an atlas of the human genome.

24 Apr 2018

Researchers find role of iron storage gene in slowing down prostate cancer growth

An abnormally high level of iron in the body is associated with prostate cancer, and researchers from the Cancer Science Institute of Singapore at the National University of Singapore may have uncovered the mechanism to explain this link.

24 Apr 2018

Role of extrachromosomal pieces of DNA in cancer development and treatment resistance

Glioblastoma is the most common and aggressive form of brain cancer. Response to standard-of-care treatment is poor, with a two-year survival rate of only 15 percent.

24 Apr 2018

Researchers discover genetic catalysts that accelerate evolution of antibiotic resistance in bacteria

Researchers at Oxford University have shown that it is possible to identify genetic catalysts that accelerate the evolution of antibiotic resistance in bacteria - and that this knowledge could be used to design treatments to stifle the development of resistance.

24 Apr 2018

Cytochalasin B-induced membrane vesicles successfully tested as vector for anti-tumor drug delivery

Extracellular vesicles (EV) represent a promising vector system for biomolecules and drug delivery due to their natural origin and participation in intercellular communication.

24 Apr 2018

NF-κB1 gene known to drive cancer development is critical for preventing stomach cancers

Melbourne researchers have made the surprise discovery that the 'odd one out' in a family of proteins known to drive cancer development is instead critical for preventing stomach cancers.

24 Apr 2018

Gene related to high fatality could be used as biomarker in patients with P. aeruginosa infection

Researchers discovered an easily measured gene linked to a high fatality rate, which could be used as a novel prognostic biomarker in patients with a Pseudomonas aeruginosa (P. aeruginosa) bloodstream infection, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases.

23 Apr 2018

Scientists examine how specific eating patterns could help fight cancer and obesity

What we eat plays a significant role in our health. The Experimental Biology 2018 meeting (EB 2018) will showcase new research into how diet could be used to fight cancer and how specific eating patterns can encourage weight loss.

23 Apr 2018

Researchers trigger E. coli’s toxin-antitoxin system to inhibit bacterial growth

According to new research, the toxin-antitoxin (TA) system found within E. coli can be induced to inhibit the growth of the bacterium. This may have important consequences for human infection.

23 Apr 2018

Researchers identify target gene in P. aeruginosa infection

Researchers have discovered a gene linked to fatal outcomes in Pseudomonas aeruginosa (P. aeruginosa) infection that could be used as a novel prognostic biomarker and treatment target.

23 Apr 2018

Salamander study provides clues for treating spinal cord injuries

One of the most vexing problems with spinal cord injuries is that the human body does not rebuild nerves once they have been damaged. Other animals, on the other hand, seem to have no problem repairing broken neurons.

23 Apr 2018

Innovative research could lead to new ways to treat, prevent cancer

Research into cancer can provide new insight into how this disease works and how it can be stopped. The Experimental Biology 2018 meeting will showcase innovative research that could lead to new ways to treat and prevent cancer.

23 Apr 2018

Study examines how higher-order gene combinations help maintain normal cell physiology

We inherit many traits from our parents including the color of our eyes and hair. Unfortunately, we also inherit risk factors for certain diseases such as cancer, heart disease, and diabetes. Understanding those genetic connections can help prevention efforts and develop new life-saving treatments to combat these diseases.

20 Apr 2018

Scientists identify gene responsible for evolution of recombination rates

Genetics is a crapshoot. During sexual reproduction, genes from both the mother and the father mix and mingle to produce a genetic combination unique to each offspring. In most cases, the chromosomes line up properly and crossover. In some unlucky cases, however, "selfish DNA" enters the mix, causing abnormal crossovers with deletions or insertions in chromosomes, which can manifest as birth defects.

20 Apr 2018

Drawbacks and benefits of using saliva for epigenetic studies

Biomarkers in saliva identify changes that impact the body, according to research published in Current Genomics. This important paper details the drawbacks and benefits of using saliva as a tissue sample for the study of epigenetic changes affected by experiences.

20 Apr 2018

Study may explain how chemoresistance evolves over time in some triple-negative breast cancers

Triple-negative breast cancer is an aggressive form of the disease accounting for 12 to 18 percent of breast cancers. It is a scary diagnosis, and even though chemotherapy can be effective as standard-of-care, many patients become resistant to treatment.

20 Apr 2018

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

20 Apr 2018

EPFL becomes part of Chan Zuckerberg’s project to develop Human Cell Atlas

"The automated single-cell analysis pipeline is a software tool that catalyzes interdisciplinary work as it allows non-expert labs to engage in high-level genomic research that otherwise would require significant computational expertise," explains Professor Bart Deplancke, director of a lab at EPFL's Institute of Bioengineering.

20 Apr 2018

Evolutionary history of tumor helps predict severity of prostate cancer

Findings from Canadian Prostate Cancer Genome Network (CPC-GENE) researchers and their collaborators, published today in Cell, show that the aggressiveness of an individual prostate cancer can be accurately assessed by looking at how that tumor has evolved. This information can be used to determine what type and how much treatment should be given to each patient, or if any is needed at all.

20 Apr 2018

Role of UBE3A enzyme in Angelman syndrome

The group, led by the Ikerbasque professor Ugo Mayor of the UPV/EHU's Department of Biochemistry and Molecular Biology, has just published in the journal Human Molecular Genetics an explanation of the mechanisms affected by Angelman syndrome.

20 Apr 2018

Gene News and Research

Latest Gene News and Research

Scientists use haploid stem cells to create an atlas of the human genome

Researchers find role of iron storage gene in slowing down prostate cancer growth

Role of extrachromosomal pieces of DNA in cancer development and treatment resistance

Researchers discover genetic catalysts that accelerate evolution of antibiotic resistance in bacteria

Cytochalasin B-induced membrane vesicles successfully tested as vector for anti-tumor drug delivery

NF-κB1 gene known to drive cancer development is critical for preventing stomach cancers

Gene related to high fatality could be used as biomarker in patients with P. aeruginosa infection

Scientists examine how specific eating patterns could help fight cancer and obesity

Researchers trigger E. coli’s toxin-antitoxin system to inhibit bacterial growth

Researchers identify target gene in P. aeruginosa infection

Salamander study provides clues for treating spinal cord injuries

Innovative research could lead to new ways to treat, prevent cancer

Study examines how higher-order gene combinations help maintain normal cell physiology

Scientists identify gene responsible for evolution of recombination rates

Drawbacks and benefits of using saliva for epigenetic studies

Study may explain how chemoresistance evolves over time in some triple-negative breast cancers

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

EPFL becomes part of Chan Zuckerberg’s project to develop Human Cell Atlas

Evolutionary history of tumor helps predict severity of prostate cancer

Role of UBE3A enzyme in Angelman syndrome

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research