Gene News and Research

Latest Gene News and Research

Penn Medicine's ODC collaborates with FAST to develop gene therapy for Angelman syndrome

Penn Medicine's Orphan Disease Center announces a new partnership with FAST to study gene therapy approaches to treat Angelman syndrome.

14 Feb 2017

Scientists identify how imbalance of calcium in mitochondria may contribute to Alzheimer's disease

Calcium in the mitochondria -- the energy factory of cells -- may be one of the keys to understanding and treating Alzheimer's disease and dementia.

14 Feb 2017

Emory researchers reveal 'matchmaker' role for protein linked to SMA

A puzzling question has lurked behind SMA, the leading genetic cause of death in infants. The disorder leads to reduced levels of the SMN protein, which is thought to be involved in processing RNA, something that occurs in every cell in the body.

14 Feb 2017

Review shows lipid nanoparticles as highly promising delivery systems in gene therapy

Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy.

14 Feb 2017

Parenting practices linked to development of children with Fragile X syndrome

University of Kansas researchers have found that certain specific parenting practices are significantly associated with the development of communication and language skills in children with Fragile X syndrome.

14 Feb 2017

Children of parents affected with C9orf72 mutations more likely to have FTD and ALS at younger age

The most common genetic cause of the brain diseases frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) is a mutation in the C9orf72 gene.

14 Feb 2017

Scientists discover population of progenitor cells linked to formation of heart’s ventricular chambers

A population of cells in early development may give rise to the ventricular chambers of the heart, but not the atria, according to a study led by researchers from the Mindich Child Health and Development Institute at the Icahn School of Medicine at Mount Sinai and published today in Nature Communications.

14 Feb 2017

New RNAi treatment safely blocks ocular inflammation in mice

Scientists have developed a new RNA interference therapeutic agent that safely blocked ocular inflammation in mice, potentially making it a new treatment for human uveitis and diabetic retinopathy.

14 Feb 2017

Study discovers how gut bacteria interacts with microRNAs to promote colon cancer growth

Gut microbes can influence the growth of colon cancer, though little is known about how they trigger the disease.

14 Feb 2017

TSRI scientists describe how key molecules in the brain work together to trigger intense anxiety

In a new study, researchers at The Scripps Research Institute have described how two important molecules in the brain work together to trigger intense anxiety.

13 Feb 2017

Gene that helps form trauma-related memories can be manipulated to prevent PTSD, study finds

A specific gene that helps form memories from traumatic events can be manipulated -- and in doing so may actually help prevent post-traumatic stress disorder (PTSD), according to a new study led NYU Langone Medical Center that recently published in Neuropharmacology.

13 Feb 2017

Study shows how errors in specific gene can cause growth defects linked to dwarfism

A new study shows how errors in a specific gene can cause growth defects associated with a rare type of dwarfism.

13 Feb 2017

Research shows how protein component of Epstein-Barr virus promotes development of cancer

After an infection with the Epstein-Barr virus (EBV), the virus persists in the body throughout a person's lifetime, usually without causing any symptoms.

13 Feb 2017

Researchers identify link between neuronal proteins and frontotemporal lobar degeneration

Frontotemporal lobar degeneration is a type of dementia characterized by personality changes, language dysfunction, and abnormal behavior. It has an earlier onset than Alzheimer's disease, and is associated with a buildup of the tau protein in affected nerve cells (neurons).

13 Feb 2017

Scientists discover 'Achilles' heel' of tumor-suppressing protein that drives prostate cancer metastasis

Researchers at Cold Spring Harbor Laboratory have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it into the cell nucleus. A study they publish today in The Journal of Cell Biology suggests that the loss of Importin-11 may destabilize PTEN, leading to the development of lung, prostate, and other cancers.

13 Feb 2017

Scientists identify new biomarkers that could guide bowel cancer treatment

Colorectal carcinomas arise in different forms, so all treatments do not work for all patients. OncoTrack, a public-private consortium supported by the Innovative Medicines Initiative Joint Undertaking, has conducted one of Europe's largest collaborative academic-industry research projects to develop and assess novel approaches for identification of new markers for colon cancer.

13 Feb 2017

Reprogramming liver cells to become pancreatic cells may help diabetic patients

It is now possible to reprogram cells from the liver into the precursor cells that give rise to the pancreas by altering the activity of a single gene.

13 Feb 2017

LMU study shows crucial role of microRNAs in protecting precursors of neurons

Programmed cell death is an integral part of embryonic development. Exploring the regulation of the process, Ludwig-Maximilians-Universitaet in Munich researchers have shown that so-called microRNAs protect the precursors of neurons from 'precocious' elimination.

13 Feb 2017

USU researchers develop new primer that improves studies into arsenic contamination

A team of Utah State University College of Engineering researchers developed a new primer - a tool used in DNA amplification - that simplifies the process of identifying bacteria found in soil and groundwater samples.

13 Feb 2017

Specific genetic errors that trigger congenital heart disease can be reproduced in common fruit fly

Specific genetic errors that trigger congenital heart disease (CHD) in humans can be reproduced reliably in Drosophila melanogaster - the common fruit fly - an initial step toward personalized therapies for patients in the future.

11 Feb 2017

Gene News and Research

Latest Gene News and Research

Penn Medicine's ODC collaborates with FAST to develop gene therapy for Angelman syndrome

Scientists identify how imbalance of calcium in mitochondria may contribute to Alzheimer's disease

Emory researchers reveal 'matchmaker' role for protein linked to SMA

Review shows lipid nanoparticles as highly promising delivery systems in gene therapy

Parenting practices linked to development of children with Fragile X syndrome

Children of parents affected with C9orf72 mutations more likely to have FTD and ALS at younger age

Scientists discover population of progenitor cells linked to formation of heart’s ventricular chambers

New RNAi treatment safely blocks ocular inflammation in mice

Study discovers how gut bacteria interacts with microRNAs to promote colon cancer growth

TSRI scientists describe how key molecules in the brain work together to trigger intense anxiety

Gene that helps form trauma-related memories can be manipulated to prevent PTSD, study finds

Study shows how errors in specific gene can cause growth defects linked to dwarfism

Research shows how protein component of Epstein-Barr virus promotes development of cancer

Researchers identify link between neuronal proteins and frontotemporal lobar degeneration

Scientists discover 'Achilles' heel' of tumor-suppressing protein that drives prostate cancer metastasis

Scientists identify new biomarkers that could guide bowel cancer treatment

Reprogramming liver cells to become pancreatic cells may help diabetic patients

LMU study shows crucial role of microRNAs in protecting precursors of neurons

USU researchers develop new primer that improves studies into arsenic contamination

Specific genetic errors that trigger congenital heart disease can be reproduced in common fruit fly

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Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research