Gene News and Research

Latest Gene News and Research

Targeted therapy for melanoma could help accelerate healing of acute, chronic wounds

A type of targeted therapy that has shown promising results treating advanced melanoma could also be used to help speed up how the skin repairs itself from injury, UCLA researchers have found, providing a potential new way to accelerate healing of acute and chronic wounds.

1 Aug 2016

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Many gene mutations that cause neurological disorders have been identified. For example, in a rare neurological disorder such as Huntington’s disease, an autosomal dominant mutation through expansion of CAG (cytosine-adenine-guanine) triplet repeats in the gene coding for the Huntingtin protein results in abnormal protein production.

1 Aug 2016

NxGEN and NX Prenatal collaborate to develop blood test for identifying women at risk of preterm birth

In a collaborative move to expand their women's health screening and testing portfolios, NxGEN MDx, LLC., and NX Prenatal Inc., announced a joint partnership to collaborate on the development and deployment of a blood test to assess pregnancy biomarkers of preterm birth risk.

30 Jul 2016

Researchers identify how precise control of inflammation could lead to bone repair

In their mission to design new biomaterials that promote tissue regeneration, Drexel University researchers have identified how inflammation, when precisely controlled, is crucial to bone repair.

30 Jul 2016

Research shows clear link between heart and the brain of LQTS patients

Researchers at the University of Rochester Medical Center recently discovered a genetic link between Long QT Syndrome (LQTS), a rare cardiac rhythm disease, and an increased risk for seizures.

29 Jul 2016

Study clarifies role of KLF12 in CRC tumor growth

Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, data demonstrate that KLF12 and EGR1 levels synergistically correlate with poor CRC prognoses.

29 Jul 2016

Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model

Investigators at Brigham and Women's Hospital have developed a hydrogel patch that can adhere to tumors in a preclinical model of colon cancer, delivering a local, combination treatment as the elastic gel breaks down over time.

29 Jul 2016

Study verifies human gene therapy in MPS I animal model

Researchers are closer to finding a better way to treat children with a rare metabolic disorder called MPS I. It is caused by a deficiency of the key enzyme IDUA needed to break down complex sugars in cells.

29 Jul 2016

Novel method sheds light on how disruption in LRRK2 gene causes inherited Parkinson's disease

Scientists have developed a new method of measuring the activity of disease-causing mutations in the LRRK2 gene, a major cause of inherited Parkinson's disease.

29 Jul 2016

UAB researchers uncover vital mechanism for L-DOPA-induced-dyskinesia

Though the drug levodopa can dramatically improve Parkinson's disease symptoms, within five years one-half of the patients using L-DOPA develop an irreversible condition -- involuntary repetitive, rapid and jerky movements.

29 Jul 2016

Study identifies two proteins crucial for self-renewal of skin stem cells

Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells. These cells continually produce new ones, which appear on the skin surface after a few days.

29 Jul 2016

Scientists identify novel way to target lung cancer through KRAS gene

UT Southwestern Medical Center researchers have identified a new way to target lung cancer through the KRAS gene, one of the most commonly mutated genes in human cancer and one researchers have so far had difficulty targeting successfully.

29 Jul 2016

New study to examine genomics of anti-platelet therapy after coronary interventions

Which antiplatelet medication is best after a coronary stent? The Tailored Antiplatelet Therapy to Lessen Outcomes After Percutaneous Coronary Intervention (TAILOR-PCI) Study examines whether prescribing heart medication based on a patient's CYP2C19 genotype will help prevent heart attack, stroke, unstable angina, and cardiovascular death in patients who undergo percutaneous coronary intervention (PCI), commonly called angioplasty.

29 Jul 2016

Blood pressure hormone system important for cardiovascular health can promote obesity

New research by University of Iowa scientists helps explain how a hormone system often targeted to treat cardiovascular disease can also lower metabolism and promote obesity.

29 Jul 2016

Study reports sampling method used for new breast cancer tests may need to be refined

Not only is breast cancer more than one disease, but a single breast cancer tumor can vary within itself, a finding that University of Pittsburgh Cancer Institute researchers discovered has the potential to lead to very different patient treatment plans depending on the tumor sample and diagnostic testing used.

28 Jul 2016

New gene therapy shows promising results for treating neurodegenerative disorders

A new gene therapy approach designed to replace the enzyme that is deficient in patients with the inherited neurodegenerative disorders Tay-Sachs and Sandhoff diseases successfully delivered the therapeutic gene to the brains of treated mice, restored enzyme function, and extended survival by about 2.5-fold.

28 Jul 2016

Gene News and Research

Latest Gene News and Research

Targeted therapy for melanoma could help accelerate healing of acute, chronic wounds

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

NxGEN and NX Prenatal collaborate to develop blood test for identifying women at risk of preterm birth

Researchers identify how precise control of inflammation could lead to bone repair

Research shows clear link between heart and the brain of LQTS patients

Study clarifies role of KLF12 in CRC tumor growth

Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model

Study verifies human gene therapy in MPS I animal model

Novel method sheds light on how disruption in LRRK2 gene causes inherited Parkinson's disease

UAB researchers uncover vital mechanism for L-DOPA-induced-dyskinesia

Study identifies two proteins crucial for self-renewal of skin stem cells

Scientists identify novel way to target lung cancer through KRAS gene

New study to examine genomics of anti-platelet therapy after coronary interventions

Blood pressure hormone system important for cardiovascular health can promote obesity

Study reports sampling method used for new breast cancer tests may need to be refined

New gene therapy shows promising results for treating neurodegenerative disorders

Researchers discover genetic changes in MSH3 gene in patients with hereditary colon cancer

Scientists identify mutation responsible for new, rare genetic disorder

Changes in the brain's pleasure center may decrease physical activity in postmenopausal women

ZMYND8 protein can suppress metastasis-linked genes in prostate cancer

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