Gene News and Research

Latest Gene News and Research

One-shot vaccine passes key preclinical test in newborn monkey models

Newborns are highly vulnerable to infections and don't respond optimally to most vaccines because their young immune systems typically mount weak antibody responses.

24 Mar 2017

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

A study published in Briefings in Functional Genomics investigated how epigenetics can modulate human's genetic program -- it can emphasize or silence genes.

24 Mar 2017

MSK scientists discover epigenetic mechanism promoting breast cancer

Researchers from Memorial Sloan Kettering Cancer Center (MSK) have identified, for the first time, an epigenetic mechanism promoting breast cancer.

24 Mar 2017

Random DNA copying ‘mistakes’ account for most cancer mutations, study finds

Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause cancer.

24 Mar 2017

Chromatrap publishes new article comparing efficiency, sensitivity of native and cross-linked ChIP-seq kits

Chromatrap has published a new article that describes a detailed genome wide comparison of native and crosslinked chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) using the company's patented solid state spin column technology.

From Chromatrap® - Porvair Sciences Ltd 24 Mar 2017

Thermo Fisher Scientific collaborates with CGT Catapult to create seamless cell and gene therapy supply chain

To help address the challenges surrounding supply chain management for cell and gene therapy around the globe, Thermo Fisher Scientific, the world leader in serving science, today announced a collaboration with the Cell and Gene Therapy Catapult to provide developers with both the manufacturing capability and distribution, logistics, and storage capacity needed to create a seamless supply chain to accelerate cell and gene therapy development and commercialsation.

From Thermo Fisher Scientific Inc. 24 Mar 2017

Research suggests novel strategy to target genetic anomaly in prostate cancers

New research suggests a novel strategy to target a genetic anomaly that occurs in half of all prostate cancers.

24 Mar 2017

SLU researchers aim to tackle diabetes and obesity by capturing benefits of exercise in pill form

With a series of new grants, Saint Louis University researchers will tackle the twin epidemics of diabetes and obesity by tapping into the potential of two nuclear receptors that control muscle metabolism.

24 Mar 2017

OTUD6B gene mutations linked to physical and intellectual deficits

An international team of researchers from institutions around the world, including Baylor College of Medicine, has discovered that mutations of the OTUD6B gene result in a spectrum of physical and intellectual deficits.

24 Mar 2017

Scientists map three-dimensional structure of protein that causes cystic fibrosis

Scientists at The Rockefeller University have mapped the three-dimensional structure for one of the more notorious disease-causing molecules in the human body: the protein responsible for the genetic disorder cystic fibrosis. And it looks fishy.

23 Mar 2017

Inner ear gene therapy holds promise for treating patients with hearing loss and dizziness

In a first-of-its-kind study published in the March 1, 2017 edition of Molecular Therapy, researchers from the National Institute on Deafness and Other Communication Disorders and Johns Hopkins University School of Medicine showed that gene therapy was able to restore balance and hearing in genetically modified mice that mimic Usher Syndrome, a genetic condition in humans characterized by partial or total hearing loss, dizziness, and vision loss that worsens over time.

23 Mar 2017

EPFL scientists develop synthetic methods to crack code of Huntington's disease

Huntington's disease is a neurodegenerative disorder that causes patients to lose their ability to move, speak, and even think. It is caused by a gene mutation that produces an abnormal form of the protein huntingtin, which aggregates and builds up inside neurons of the cortex and striatum.

23 Mar 2017

MSU lands $727,000 NIH grant to improve use of fish as disease models for human medicine

Michigan State University has landed a $727,000 grant from the National Institutes of Health to improve the use of fish as disease models for human medicine.

23 Mar 2017

Researchers uncover major clue to how mucus becomes abnormal in CF airways

People with cystic fibrosis (CF) suffer repeated lung infections because their airway mucus is too thick and sticky to keep bacteria, viruses, and other pathogens from causing chronic infection.

23 Mar 2017

Genome sequencing approach opens door to therapy options for rare, neglected cancers

An international team of scientists led by the Icahn School of Medicine at Mount Sinai and UConn School of Medicine have reported the results of a genome sequencing study for an extremely rare form of cancer.

23 Mar 2017

Researchers identify odorant troenan that can inhibit colorectal cancer growth

Growth of colorectal cancer cells can be inhibited with the odorant troenan. This is reported by the research team headed by Prof Dr Dr Dr habil. Hanns Hatt and Dr Lea Weber from Ruhr-Universität Bochum in the journal "PLOS One".

23 Mar 2017

Researchers unravel how drug interacts with ribosome to halt protein production

The discovery of a chemical compound that halts the production of a small set of proteins while leaving general protein production untouched suggests a new drug search strategy: Find compounds that target undesired proteins before they are even made.

23 Mar 2017

Androgens more important for ovarian development, study suggests

Scientists have discovered that the male "androgen" hormone is an important element in the ovarian development of female chicken embryos, more so than in the development of male testes.

23 Mar 2017

Method used to pick up laboratory mice has major impact on result of mouse studies

A new study shows that how mice are picked up by the experimenter can substantially change their behaviour in cognitive tests. The work, by Dr Kelly Gouveia and Professor Jane Hurst from the University of Liverpool, was published in Scientific Reports today and funded by the NC3Rs .

23 Mar 2017

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

23 Mar 2017

Gene News and Research

Latest Gene News and Research

One-shot vaccine passes key preclinical test in newborn monkey models

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

MSK scientists discover epigenetic mechanism promoting breast cancer

Random DNA copying ‘mistakes’ account for most cancer mutations, study finds

Chromatrap publishes new article comparing efficiency, sensitivity of native and cross-linked ChIP-seq kits

Thermo Fisher Scientific collaborates with CGT Catapult to create seamless cell and gene therapy supply chain

Research suggests novel strategy to target genetic anomaly in prostate cancers

SLU researchers aim to tackle diabetes and obesity by capturing benefits of exercise in pill form

OTUD6B gene mutations linked to physical and intellectual deficits

Scientists map three-dimensional structure of protein that causes cystic fibrosis

Inner ear gene therapy holds promise for treating patients with hearing loss and dizziness

EPFL scientists develop synthetic methods to crack code of Huntington's disease

MSU lands $727,000 NIH grant to improve use of fish as disease models for human medicine

Researchers uncover major clue to how mucus becomes abnormal in CF airways

Genome sequencing approach opens door to therapy options for rare, neglected cancers

Researchers identify odorant troenan that can inhibit colorectal cancer growth

Researchers unravel how drug interacts with ribosome to halt protein production

Androgens more important for ovarian development, study suggests

Method used to pick up laboratory mice has major impact on result of mouse studies

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)