Gene News and Research

Latest Gene News and Research

Stem cell secretions appear to protect retinal ganglion cells in rats, study shows

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye.

27 Jan 2017

New gene therapy for Pompe disease may replace currently available treatments

After decades investigating a rare, life-threatening condition that cripples the muscles, Duke Health researchers have developed a gene therapy they hope could enhance or even replace the only FDA-approved treatment currently available to patients.

27 Jan 2017

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

Using a novel form of gene therapy, scientists from Harvard Medical School and the Massachusetts General Hospital have managed to restore partial hearing and balance in mice born with a genetic condition that affects both.

27 Jan 2017

Old tuberculosis drug improves impaired social behavior in autism mouse model

Reducing the function of the autism-associated gene Pcdh10 leads to impairments in social behavior, according to a study published in Biological Psychiatry.

26 Jan 2017

Researchers identify novel risk genes linked to bipolar disorder

Bipolar disorder (BD), characterized by mood swings between positive manic/hypomanic and negative/depressive states, is a common psychiatric disorder with a lifetime prevalence of ~1%.

26 Jan 2017

Missing gene may cause kidney and urinary tract defects in people with DiGeorge syndrome

Loss of function of the CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome, a multinational team of scientists led by Columbia University Medical Center has found.

25 Jan 2017

Researchers map genetic changes resulting from short bowel syndrome

Investigators at Children's Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome using a novel zebrafish model and by performing intensive gene sequencing.

25 Jan 2017

Study suggests best sequence of therapies for brain metastases in EGFR mutant lung cancer patients

About 10 percent of lung cancers in the United States and as many as 40 percent in Asia are driven by mutations in the EGFR gene.

25 Jan 2017

HCI scientists uncover new way that bones get destroyed through breast cancer

Once breast cancer spreads through the body, it can degrade a patient's healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute at the University of Utah have identified a new way that bones get destroyed through cancer.

25 Jan 2017

Prenatal infection-induced epigenetic modifications may alter brain development in offspring

Maternal infection during pregnancy increases the risk for psychiatric disorders in the child, but the path between the two is something of a mystery.

25 Jan 2017

BRCA1 gene required for survival of blood forming stem cells, UT Southwestern study finds

Researchers at from the Harold C. Simmons Comprehensive Cancer Center have found that the BRCA1 gene is required for the survival of blood forming stem cells, which could explain why patients with BRCA1 mutations do not have an elevated risk for leukemia.

25 Jan 2017

Scientists discover new way to inhibit growth of glioblastoma

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

25 Jan 2017

Scientists develop new method to accurately determine gene expression in single cells

At Baylor College of Medicine, scientists have developed a method that allows them to accurately determine the genes expressed in single cells.

25 Jan 2017

Faults in natural waste disposal system may play key role in neurodegenerative diseases

A fault with the natural waste disposal system that helps to keep our brain cell 'batteries' healthy may contribute to neurodegenerative disease, a new study has found.

25 Jan 2017

In utero environment can impact brain development, study shows

A new study shows that what happens to a fetus in the womb can affect the brain later in life.

25 Jan 2017

Timing of chemotherapy can have big effect on inflammation, study shows

The time of day that breast cancer chemotherapy drugs are given affects the amount of damaging inflammation in the body, a new study in mice suggests.

24 Jan 2017

Study provides insights into molecular mechanisms of ZIKV infection

Zika virus (ZIKV) interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes guiding the formation and development of neurons and astrocytes, according to findings released on January 23rd 2017 at Scientific Reports.

24 Jan 2017

Advanced NMR-based methods for studying RNPs and drug design

Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical tool widely used in chemical research to investigate the structure and dynamics of molecules.

From Bruker BioSpin Group 24 Jan 2017

Cervicovaginal microbial communities in pregnant woman may be key to preventing preterm birth

A team of researchers that has confirmed the presence of bacteria in a woman's vagina and cervix may either increase the risk of premature birth or have a protective effect against it, has won the March of Dimes Award for Best Abstract on Prematurity at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting. The findings will be presented Thursday, January 26, at 1:15 p.m. PST at Caesars Palace Augustus Ballroom in Las Vegas.

24 Jan 2017

Study identifies conserved role for Ovo protein in controlling germline development in mice and fruit flies

Germline cells are the only cells that develop into eggs or sperm, while somatic cells develop into the body. Progenitors of the germline, known as primordial germ cells (PGCs), differentiate into eggs or sperm after embryonic development.

24 Jan 2017

Gene News and Research

Latest Gene News and Research

Stem cell secretions appear to protect retinal ganglion cells in rats, study shows

New gene therapy for Pompe disease may replace currently available treatments

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

Old tuberculosis drug improves impaired social behavior in autism mouse model

Researchers identify novel risk genes linked to bipolar disorder

Missing gene may cause kidney and urinary tract defects in people with DiGeorge syndrome

Researchers map genetic changes resulting from short bowel syndrome

Study suggests best sequence of therapies for brain metastases in EGFR mutant lung cancer patients

HCI scientists uncover new way that bones get destroyed through breast cancer

Prenatal infection-induced epigenetic modifications may alter brain development in offspring

BRCA1 gene required for survival of blood forming stem cells, UT Southwestern study finds

Scientists discover new way to inhibit growth of glioblastoma

Scientists develop new method to accurately determine gene expression in single cells

Faults in natural waste disposal system may play key role in neurodegenerative diseases

In utero environment can impact brain development, study shows

Timing of chemotherapy can have big effect on inflammation, study shows

Study provides insights into molecular mechanisms of ZIKV infection

Advanced NMR-based methods for studying RNPs and drug design

Cervicovaginal microbial communities in pregnant woman may be key to preventing preterm birth

Study identifies conserved role for Ovo protein in controlling germline development in mice and fruit flies

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research