Gene News and Research

Latest Gene News and Research

Research could help develop better therapies for new subtype of adenocarcinoma patients

Lung cancer is the most common cause of cancer deaths, accounting for about a third of all tumor-related deaths. Adenocarcinomas, a non-small cell lung cancer (NSCLC), account for about 40 percent of cancer diagnoses, but few treatments are available for the disease.

4 Aug 2016

New tool helps researchers make connections between proteins, genes, drugs and diseases

Every day, more than 3,000 new abstracts are uploaded to PubMed, the main biomedical literature reference database. Even in a researcher's narrowly-defined field, it is impossible to stay on top of the ever-evolving webs of interconnections between these papers.

4 Aug 2016

Research findings may have implications for ALS and other neurological disorders

Amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease) is a progressive disorder that devastates motor nerve cells. People diagnosed with ALS slowly lose the ability to control muscle movement, and are ultimately unable to speak, eat, move, or breathe.

4 Aug 2016

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases.

4 Aug 2016

NIH launches clinical trial of experimental vaccine candidate for preventing Zika virus infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched a clinical trial of a vaccine candidate intended to prevent Zika virus infection.

3 Aug 2016

New biochip test helps identify individuals at increased risk of Alzheimer's disease

Researchers today unveiled results from a new blood test to help identify which patients are at an elevated risk of Alzheimer's disease.

3 Aug 2016

Scientists uncover genetic cause of rare pediatric progressive neuropathy

Researchers from the National Institutes of Health and their colleagues identified the genetic cause and a possible therapeutic target for a rare form of pediatric progressive neuropathy.

3 Aug 2016

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Rice University bioengineer Junghae Suh has been awarded a prestigious R01 grant by the National Institutes of Health to research the use of viral gene therapy to fight ovarian cancer.

3 Aug 2016

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs.

3 Aug 2016

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Scientists have engineered a sort of biological barbell that can get inside cancer cells and do damage to two proteins that work independently and together to enable cancer's survival and spread.

3 Aug 2016

Lower weight late in life linked to greater risk for Alzheimer's disease

Researchers at Brigham and Women's Hospital and Massachusetts General Hospital have found an association between lower weight and more extensive deposits of the Alzheimer's-associated protein beta-amyloid in the brains of cognitively normal older individuals.

2 Aug 2016

Next-generation sequencing to evaluate cell-free DNA yields more accurate results in diagnosis of MDS

Using next-generation sequencing (NGS) methods to analyze cell-free DNA in the blood of patients with myelodysplastic syndrome (MDS) yields more accurate results than the current standard approach of Sanger sequencing.

2 Aug 2016

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

UT Southwestern Medical Center researchers have found an important innate immunity role for a gene linked to a rare, fatal syndrome in children. Their study has implications for a much more common disease: tuberculosis.

2 Aug 2016

Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Researchers at the Johns Hopkins Kimmel Cancer Center say they have developed a system that uses transformed human stem cells to speed up screening of existing drugs that might work against rare brain and other cancers.

2 Aug 2016

Researchers shed light on mechanism for inducing memory B cell differentiation

A group of researchers at Immunology Frontier Research Center (IFReC), Osaka University and RIKEN Center for Integrative Medical Sciences jointly clarified the mechanism for inducing germinal-center B cells' differentiation into memory B cells, immune cells that remember antigens, at the molecular level.

2 Aug 2016

TSRI study unveils new twist in immune biology

A new study, led by scientists at The Scripps Research Institute, reveals a surprising twist in immune biology.

2 Aug 2016

Paternal over-nutrition may lead to generational obesity and metabolic dysfunction

Paternal intake of a high-fat diet (HFD) can cause genetic changes that lead to generational obesity and metabolic dysfunction—including body weight and fat mass increases and changes in blood pressure, triglyceride levels and fat metabolism—in mice, according to Japanese researchers at Okayama University.

2 Aug 2016

Researchers use machine-learning approach to predict autism risk genes

Princeton University and Simons Foundation researchers have developed a machine-learning approach that for the first time analyzes the entire human genome to predict which genes may cause autism spectrum disorder, raising the number of genes that could be linked to the disorder from 65 to 2,500.

1 Aug 2016

Study finds mutations in three new genes can cause rare syndromic CHD disorders

Researchers at The University of Nottingham have been involved in one of the largest international studies of congenital heart disease, which has discovered gene mutations linked to three new rare congenital heart disorders (CHD).

1 Aug 2016

Scientists uncover novel sites of expression in the brain for gene linked to ALS and FTD

For the first time novel expression sites in the brain have been identified for a gene which is associated with Motor Neuron Disease and Frontotemporal Dementia.

1 Aug 2016

Gene News and Research

Latest Gene News and Research

Research could help develop better therapies for new subtype of adenocarcinoma patients

New tool helps researchers make connections between proteins, genes, drugs and diseases

Research findings may have implications for ALS and other neurological disorders

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

NIH launches clinical trial of experimental vaccine candidate for preventing Zika virus infection

New biochip test helps identify individuals at increased risk of Alzheimer's disease

Scientists uncover genetic cause of rare pediatric progressive neuropathy

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Lower weight late in life linked to greater risk for Alzheimer's disease

Next-generation sequencing to evaluate cell-free DNA yields more accurate results in diagnosis of MDS

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Researchers shed light on mechanism for inducing memory B cell differentiation

TSRI study unveils new twist in immune biology

Paternal over-nutrition may lead to generational obesity and metabolic dysfunction

Researchers use machine-learning approach to predict autism risk genes

Study finds mutations in three new genes can cause rare syndromic CHD disorders

Scientists uncover novel sites of expression in the brain for gene linked to ALS and FTD

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