Gene News and Research

Latest Gene News and Research

Melanoma research breakthrough opens up new pathways to treatment

A QUT-driven project has identified the way in which melanoma cells spread, opening up new pathways to treatment via drugs to 'turn off' the invasive gene.

7 Feb 2017

Researchers create first animal model of rare disease linked to problem of adrenal glands

The name of the gene is Armc5, for Armadillo repeat containing 5. Until now, its function was unknown. After 10 years of research, a team at the University of Montreal Hospital Research Centrehas succeeded in deleting this gene in experimental mice and discovered that its loss gives rise to a heretofore unidentified syndrome.

7 Feb 2017

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

One of the most promising areas of cancer research is personalized therapy using precision medicine. The National Cancer Institute's NCI-MATCH is a large, ongoing clinical trial that matches tumors to therapies based on the tumor's genetic characteristics.

7 Feb 2017

Scientists find new method for identifying therapeutic targets in cancers lacking tumor suppressor genes

A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes.

7 Feb 2017

Uterine glands produce several key factors for embryo growth and pregnancies, study shows

The majority of pregnancy losses occur during the first trimester, when biological communication between the embryo and mother is critical for the establishment of the pregnancy.

7 Feb 2017

Scientists show how immune receptor activated by bacteria contributes to diabetic bladder dysfunction

Bladder dysfunction is a reality for about half of patients with diabetes and now scientists have evidence that an immune system receptor that's more typically activated by bacteria is a major contributor.

7 Feb 2017

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

For many newborn babies, an enzyme that breaks down the molecule bilirubin doesn't activate right away. The resulting bilirubin buildup can lead to jaundice, a typically harmless condition that causes a baby's skin to temporarily appear yellow.

6 Feb 2017

Northwestern Medicine scientists discover retinal cell that may cause myopia

Northwestern Medicine scientists have discovered a cell in the retina that may cause myopia when it dysfunctions. The dysfunction may be linked to the amount of time a child spends indoors and away from natural light.

6 Feb 2017

Scientists evaluate rapid test that detects colistin resistance gene in bacterial isolates

Colistin is used as the "last-resort antibiotic" for dreaded multidrug-resistant pathogens, especially in hospitals. However, gut bacteria that have become insensitive to colistin now exist -- owing to the mobile resistance gene mcr-1. In early 2016, bacteria carrying this resistance gene were detected in Germany for the first time.

6 Feb 2017

Researchers evaluate biological effects of exposure to cigarette smoke versus e-cigarette aerosols

Researchers reported changes in the expression levels of 123 genes when reconstituted lung tissue was exposed to cigarette smoke, compared to only two genes that could be confirmed following exposure to e-cigarette aerosols.

6 Feb 2017

PERK protein could be target for development of new drugs for progressive supranuclear palsy

The brain disease "progressive supranuclear palsy" (PSP) is currently incurable and its symptoms can only be eased to a very limited degree. PSP impairs eye movements, locomotion, balance control, and speech.

6 Feb 2017

Studies reveal link between rotator cuff disease and genetics

A new study presented this week at the Association of Academic Physiatrists Annual Meeting in Las Vegas shows rotator cuff disease might be a heritable trait.

6 Feb 2017

Cancer drug could promote regeneration of damaged heart muscle, research shows

An anticancer agent in development promotes regeneration of damaged heart muscle 0- an unexpected research finding that may help prevent congestive heart failure in the future.

3 Feb 2017

Penn scientists find cytokine as key to fighting and treating viral infection in the lungs

Viral infections that occur in a patient's lungs are a significant cause of hospitalization and death among children and the elderly.

3 Feb 2017

Single Molecule Detection of Proteins in Single Cells

We developed this technology almost 10 years ago. It was developed after a key experiment was carried out by David Rissin, who was a PhD candidate in my laboratory at the time.

From Pittcon 3 Feb 2017

GIANT study uncovers new, rare DNA changes that affect human height

In the largest, deepest search to date, the international Genetic Investigation of Anthropometric Traits Consortium has uncovered 83 new DNA changes that affect human height.

3 Feb 2017

Sleep may be regulated by several brain-based immune proteins, study reveals

Sleep -- one of the most basic, yet most mystifying processes of the human body -- has confounded physicians, scientists and evolutionary biologists for centuries.

2 Feb 2017

Research unravels molecular mechanisms of antisense oligonucleotides

Stanley T. Crooke, MD, PhD, CEO of Ionis Pharmaceuticals and recipient of the 2016 Lifetime Achievement Award from the Oligonucleotide Therapeutic Society presents a detailed look at the mechanisms that underlie antisense drug activity in the article entitled "Molecular Mechanisms of Antisense Oligonucleotides," published in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

2 Feb 2017

Study finds impaired secretion of stress hormone in healthy Indigenous young adults

James Cook University scientists have made a disturbing finding about some young Indigenous people's biological reaction to stress, but one that could help close the health gap for indigenous people.

2 Feb 2017

New study offers insights into how antidepressants work in the brain

When they work, antidepressant medications may take weeks or months to alleviate symptoms of depression.

2 Feb 2017

Gene News and Research

Latest Gene News and Research

Melanoma research breakthrough opens up new pathways to treatment

Researchers create first animal model of rare disease linked to problem of adrenal glands

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

Scientists find new method for identifying therapeutic targets in cancers lacking tumor suppressor genes

Uterine glands produce several key factors for embryo growth and pregnancies, study shows

Scientists show how immune receptor activated by bacteria contributes to diabetic bladder dysfunction

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

Northwestern Medicine scientists discover retinal cell that may cause myopia

Scientists evaluate rapid test that detects colistin resistance gene in bacterial isolates

Researchers evaluate biological effects of exposure to cigarette smoke versus e-cigarette aerosols

PERK protein could be target for development of new drugs for progressive supranuclear palsy

Studies reveal link between rotator cuff disease and genetics

Cancer drug could promote regeneration of damaged heart muscle, research shows

Penn scientists find cytokine as key to fighting and treating viral infection in the lungs

Single Molecule Detection of Proteins in Single Cells

GIANT study uncovers new, rare DNA changes that affect human height

Sleep may be regulated by several brain-based immune proteins, study reveals

Research unravels molecular mechanisms of antisense oligonucleotides

Study finds impaired secretion of stress hormone in healthy Indigenous young adults

New study offers insights into how antidepressants work in the brain

Genomics - Industry Focus eBook (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research