Gene News and Research

Latest Gene News and Research

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

UT Southwestern Medical Center researchers have found an important innate immunity role for a gene linked to a rare, fatal syndrome in children. Their study has implications for a much more common disease: tuberculosis.

2 Aug 2016

Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Researchers at the Johns Hopkins Kimmel Cancer Center say they have developed a system that uses transformed human stem cells to speed up screening of existing drugs that might work against rare brain and other cancers.

2 Aug 2016

Researchers shed light on mechanism for inducing memory B cell differentiation

A group of researchers at Immunology Frontier Research Center (IFReC), Osaka University and RIKEN Center for Integrative Medical Sciences jointly clarified the mechanism for inducing germinal-center B cells' differentiation into memory B cells, immune cells that remember antigens, at the molecular level.

2 Aug 2016

TSRI study unveils new twist in immune biology

A new study, led by scientists at The Scripps Research Institute, reveals a surprising twist in immune biology.

2 Aug 2016

Paternal over-nutrition may lead to generational obesity and metabolic dysfunction

Paternal intake of a high-fat diet (HFD) can cause genetic changes that lead to generational obesity and metabolic dysfunction—including body weight and fat mass increases and changes in blood pressure, triglyceride levels and fat metabolism—in mice, according to Japanese researchers at Okayama University.

2 Aug 2016

Researchers use machine-learning approach to predict autism risk genes

Princeton University and Simons Foundation researchers have developed a machine-learning approach that for the first time analyzes the entire human genome to predict which genes may cause autism spectrum disorder, raising the number of genes that could be linked to the disorder from 65 to 2,500.

1 Aug 2016

Study finds mutations in three new genes can cause rare syndromic CHD disorders

Researchers at The University of Nottingham have been involved in one of the largest international studies of congenital heart disease, which has discovered gene mutations linked to three new rare congenital heart disorders (CHD).

1 Aug 2016

Scientists uncover novel sites of expression in the brain for gene linked to ALS and FTD

For the first time novel expression sites in the brain have been identified for a gene which is associated with Motor Neuron Disease and Frontotemporal Dementia.

1 Aug 2016

Targeted therapy for melanoma could help accelerate healing of acute, chronic wounds

A type of targeted therapy that has shown promising results treating advanced melanoma could also be used to help speed up how the skin repairs itself from injury, UCLA researchers have found, providing a potential new way to accelerate healing of acute and chronic wounds.

1 Aug 2016

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Many gene mutations that cause neurological disorders have been identified. For example, in a rare neurological disorder such as Huntington’s disease, an autosomal dominant mutation through expansion of CAG (cytosine-adenine-guanine) triplet repeats in the gene coding for the Huntingtin protein results in abnormal protein production.

1 Aug 2016

NxGEN and NX Prenatal collaborate to develop blood test for identifying women at risk of preterm birth

In a collaborative move to expand their women's health screening and testing portfolios, NxGEN MDx, LLC., and NX Prenatal Inc., announced a joint partnership to collaborate on the development and deployment of a blood test to assess pregnancy biomarkers of preterm birth risk.

30 Jul 2016

Researchers identify how precise control of inflammation could lead to bone repair

In their mission to design new biomaterials that promote tissue regeneration, Drexel University researchers have identified how inflammation, when precisely controlled, is crucial to bone repair.

30 Jul 2016

Research shows clear link between heart and the brain of LQTS patients

Researchers at the University of Rochester Medical Center recently discovered a genetic link between Long QT Syndrome (LQTS), a rare cardiac rhythm disease, and an increased risk for seizures.

29 Jul 2016

Study clarifies role of KLF12 in CRC tumor growth

Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, data demonstrate that KLF12 and EGR1 levels synergistically correlate with poor CRC prognoses.

29 Jul 2016

Gene News and Research

Latest Gene News and Research

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Researchers shed light on mechanism for inducing memory B cell differentiation

TSRI study unveils new twist in immune biology

Paternal over-nutrition may lead to generational obesity and metabolic dysfunction

Researchers use machine-learning approach to predict autism risk genes

Study finds mutations in three new genes can cause rare syndromic CHD disorders

Scientists uncover novel sites of expression in the brain for gene linked to ALS and FTD

Targeted therapy for melanoma could help accelerate healing of acute, chronic wounds

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

NxGEN and NX Prenatal collaborate to develop blood test for identifying women at risk of preterm birth

Researchers identify how precise control of inflammation could lead to bone repair

Research shows clear link between heart and the brain of LQTS patients

Study clarifies role of KLF12 in CRC tumor growth

Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model

Study verifies human gene therapy in MPS I animal model

Novel method sheds light on how disruption in LRRK2 gene causes inherited Parkinson's disease

UAB researchers uncover vital mechanism for L-DOPA-induced-dyskinesia

Study identifies two proteins crucial for self-renewal of skin stem cells

Scientists identify novel way to target lung cancer through KRAS gene

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting