Genetics News and Research

Latest Genetics News and Research

Gene silencing and microRNA discovery

One of the body's primary strategies for regulating its genome is a kind of targeted gene silencing orchestrated by small molecules called microRNAs, or miRNAs.

7 Nov 2005

Largest study to date on risk factors associated with primary biliary cirrhosis

A case-control study of more than 2000 people has identified a number of factors that may induce primary biliary cirrhosis (PBC) in genetically susceptible individuals. These include a history of urinary tract infections, hormone replacement therapy, tobacco use, and nail polish use.

3 Nov 2005

Substance found in evening primrose oil inhibits breast cancer gene

Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers, Northwestern University researchers report.

3 Nov 2005

Fundamental insight about protein evolution

While searching for new targets for malaria drugs and vaccines, a team including a Howard Hughes Medical Institute (HHMI) medical student fellow reached a fundamental insight about evolution: different species make use of similar sets of proteins in different ways.

3 Nov 2005

First steps taken to treat human hereditary blindness

A team led by Krzysztof Palczewski, Ph.D., chair of pharmacology at the Case Western Reserve University School of Medicine, has taken the first steps in treating an eye disease causing irreversible congenital blindness in millions of people worldwide by successfully testing two new treatments in mice.

3 Nov 2005

New findings on bacterial vaginosis

Despite being one of the most common infections among women, scientists and doctors know little about the causes of bacterial vaginosis (BV), a usually benign disease that is also linked to serious health problems including pelvic inflammatory disease

3 Nov 2005

Important breakthrough in developing the drugs of the future

Their work on targeting individual genes for more effective and cheaper drug testing opens the way to treatments for a huge range of diseases including diabetes and atherosclerosis, which leads to strokes and heart attacks.

3 Nov 2005

Tongues have a taste for fatty food

According to a new study French scientists say our tongues have an ability to detect fat in the diet which may explain our love of cheesecake, french fries and butter cookies.

2 Nov 2005

Protein called CHIP helps untangle protein misfolding in brain disease

Keeping the body and mind healthy depends on keeping cells healthy and functioning. This means that cells need a very robust quality-control system to repair or remove damaged or misshapen proteins. Protein handling is especially important in neurons because damage or death of brain cells causes neurological disease.

1 Nov 2005

New way to generate genetically altered influenza virus

In the event of an influenza pandemic, the world's vaccine manufacturers will be in a race against time to forestall calamity.

1 Nov 2005

Researchers determine how Tsg101 gene controls cellular growth

Researchers at Emory University School of Medicine and their colleagues have discovered a genetic mechanism that controls cellular growth in the fruit fly Drosophila melanogaster, and believe it likely that a similar system may be at work in normal and cancerous human cells.

1 Nov 2005

Unique approach to enhance the immune system in patients with breast or colorectal cancer

The study uses a potent immune-enhancing gene delivered directly into the cancer cells to make them look foreign to the body's immune system, which will then attack and destroy the cancer.

1 Nov 2005

Treatment for Leber Congenital Amaurosis

U.S. researchers have taken the first steps in treating an eye disease that causes irreversible blindness in humans by successfully testing two novel treatments in mice.

1 Nov 2005

At least two "diabetes genes" predict the risk of Type 2 diabete

Scandinavian researchers have confirmed that at least two "diabetes genes" predict the risk of Type 2 diabetes (T2D) when combined with lifestyle factors, in the largest study of its kind to date.

1 Nov 2005

New technique provides supplies of seed viruses to fight bird flu

Researchers in the U.S. believe that a new manufacturing method may allow large quantities of vaccine to quickly be deployed against a deadly bird flu pandemic.

1 Nov 2005

Gene fusion appears to cause prostate cancer

Scientists at the University of Michigan Medical School, in collaboration with researchers at Harvard's Brigham and Women's Hospital, have discovered a recurring pattern of scrambled chromosomes and abnormal gene activity that occurs only in prostate cancer.

30 Oct 2005

DCDC2 gene linked to dyslexia

Pediatric researchers at Yale School of Medicine have identified a gene on human chromosome 6 called DCDC2, which is linked to dyslexia, a reading disability affecting millions of children and adults.

30 Oct 2005

Novel mouse model of medulloblastoma

A collaboration of researchers, led by Dr. Martine Roussel of St. Jude Children's Research Hospital, has developed a novel mouse model of medulloblastoma -- the most prevalent malignant pediatric brain tumor -- that the researchers hope will more accurately represent the genetic changes involved in human brain tumor development.

30 Oct 2005

Gene involved in B-cell development might play a role in multiple sclerosis

The results of a large study published today in the open access journal BMC Neurology reveal that multiple sclerosis (MS) patients are more likely to carry two specific genetic variations in the Early B-cell factor gene (EBF-1), than healthy individuals.

30 Oct 2005

Cichlid fish provide better understanding of the genetic factors that regulate bone shape

Researchers at the Forsyth Institute have discovered that the genes that influence the jaws of cichlid fish, tropical freshwater fish renowned for head shape diversity, offer insight into overall vertebrate diversity.

30 Oct 2005