Genetics News and Research

Latest Genetics News and Research

Oral therapeutic drug shows promise against recurrent C. difficile infection

Results from a Phase 1b/2 trial suggest that an investigational microbiome-based, oral therapeutic drug is effective for the treatment of recurrent C. difficile infection. In a paper published online in the Journal of Infectious Diseases, a multi-institutional research team reports that treatment with the preparation, containing the spores of approximately 50 species of beneficial bacteria, successfully prevented recurrence of C. difficile infection (CDI) in patients with a history of multiple recurrent disease.

10 Feb 2016

Penn investigators devise new method to map 'transcriptome'

A new way of mapping the "transcriptome" -- the collection of RNA read-outs that are expressed by a cell's active genes -- has been devised by researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Feb 2016

Temple team describes use of cadaver DNA to advance genetics learning in medical curriculum

Cadavers have long been one of the most important resources for anatomy teaching in medical school. Now, they are also at the forefront of cutting-edge genetics teaching, thanks to innovative thinking by professors at the Lewis Katz School of Medicine at Temple University.

10 Feb 2016

UC San Diego School of Medicine launches new NAFLD Research Center

Roughly one-quarter of all Americans - an estimated 100 million adults and children - have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure.

9 Feb 2016

Medical marijuana offers hope for kids with uncontrolled seizures

Desperate for relief, parents are taking unusual steps to help children plagued with seizures. The relief, however, comes in a most unlikely form: marijuana.

9 Feb 2016

UM SOM researchers reveal genetic makeup of various strains of E. coli

A multi-disciplinary group of researchers at the University of Maryland School of Medicine have for the first time determined the genetic makeup of various strains of E. coli, which every year kills hundreds of thousands of people around the world.

9 Feb 2016

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

An experimental nanoparticle therapy that combines low-density lipoproteins (LDL) and fish oil preferentially kills primary liver cancer cells without harming healthy cells, UT Southwestern Medical Center researchers report.

9 Feb 2016

TBX5 gene expression could play key role in congenital heart disease

Congenital heart disease is the most common birth defect and the leading cause of all infant deaths in the United States. Mutations in the gene TBX5 have been shown to cause both rare and more prevalent forms of congenital heart disease, yet the underlying mechanisms have remained unclear.

9 Feb 2016

Study shows association between traffic-related air pollution and dark spots on the skin

A largescale study that included women from Germany and China has demonstrated a link between levels of traffic-related air pollution and air pollution-associated gases with the formation of dark spots on the skin, known as lentigenes. The most pronounced changes were observed on the cheeks of Asian women over the age of 50.

8 Feb 2016

Researchers reveal direct link between Wbp2 gene and progressive hearing loss

Researchers at King's College London and the Wellcome Trust Sanger Institute in the United Kingdom have for the first time demonstrated a direct link between the Wbp2 gene and progressive hearing loss. The scientists report that the loss of Wbp2 expression leads to progressive high-frequency hearing loss in mouse as well as in two clinical cases of children with deafness with no other obvious features.

8 Feb 2016

Study reveals association between DNA methylation and type 2 diabetes

Researchers from the Hospital del Mar Medical Research Institute have found an epigenetic mechanism implicated in the regulation of blood sugar. The study, published in the journal Molecular Human Genetics, reveals that the methylation of the TXNIP gene is associated with diabetes mellitus type 2 and, in particular, average blood glucose levels.

8 Feb 2016

Aggression influences new nerve cell production in the brain

A group of neurobiologists from Russia and the USA, including Dmitry Smagin, Tatyana Michurina, and Grigori Enikolopov from Moscow Institute of Physics and Technology, have proven experimentally that aggression has an influence on the production of new nerve cells in the brain.

8 Feb 2016

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity.

5 Feb 2016

Bowel Cancer UK's new landmark study aims to identify critical gaps in current bowel cancer research

Bowel Cancer UK is announcing on World Cancer Day (Thursday 4 February) a new research project which will bring together 100 clinicians and scientists to identify gaps in current research into bowel cancer which, if addressed, will help save the lives of thousands of people diagnosed with the disease.

5 Feb 2016

New method could help scientists conduct in-depth research on malignant tumors in cancer patients

Scientists at the Children's Medical Center Research Institute at UT Southwestern have pioneered a new method for conducting in-depth research on malignant tumors in patients, in the process discovering new complexities underlying cancer biology and overturning a nearly century-old perception about cancer metabolism.

5 Feb 2016

CMU joins $12 million research project to reverse-engineer the brain's secret algorithms

Carnegie Mellon University is embarking on a five-year, $12 million research effort to reverse-engineer the brain, seeking to unlock the secrets of neural circuitry and the brain's learning methods. Researchers will use these insights to make computers think more like humans.

4 Feb 2016

New research identifies key enzyme linked to age-related increases in cancer and inflammation

For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

4 Feb 2016

Genetic variants associated with preference to mornings or nights

23andMe, Inc., the leading personal genetics company, today announced the results of a genome-wide association study (GWAS) identifying genetic variants associated with being a morning person.

3 Feb 2016

Study reveals fetal origin for social and repetitive behavior deficits

Fetal development has been known to play an important role in social interaction, a fundamental behavior found in nearly all organisms, and later adult social behaviors. Autism, a highly heritable neurodevelopment disorder that causes difficulties with social interactions, has been postulated to be caused by neuron overgrowth in the prenatal period, although the precise timing and cause of this overgrowth has been unknown.

3 Feb 2016

'Housekeeping' gene may have a link to male infertility

Researchers at Iowa State University have found evidence that a "housekeeping" gene present in every cell of the body may have a link to male infertility.

3 Feb 2016

Genetics News and Research

Latest Genetics News and Research

Oral therapeutic drug shows promise against recurrent C. difficile infection

Penn investigators devise new method to map 'transcriptome'

Temple team describes use of cadaver DNA to advance genetics learning in medical curriculum

UC San Diego School of Medicine launches new NAFLD Research Center

Medical marijuana offers hope for kids with uncontrolled seizures

UM SOM researchers reveal genetic makeup of various strains of E. coli

Experimental nanoparticle therapy shows promise for fighting primary liver cancer

TBX5 gene expression could play key role in congenital heart disease

Study shows association between traffic-related air pollution and dark spots on the skin

Researchers reveal direct link between Wbp2 gene and progressive hearing loss

Study reveals association between DNA methylation and type 2 diabetes

Aggression influences new nerve cell production in the brain

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

Bowel Cancer UK's new landmark study aims to identify critical gaps in current bowel cancer research

New method could help scientists conduct in-depth research on malignant tumors in cancer patients

CMU joins $12 million research project to reverse-engineer the brain's secret algorithms

New research identifies key enzyme linked to age-related increases in cancer and inflammation

Genetic variants associated with preference to mornings or nights

Study reveals fetal origin for social and repetitive behavior deficits

'Housekeeping' gene may have a link to male infertility

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging