Genetics News and Research

Latest Genetics News and Research

Discovery leads to new understanding of cancer metastasis

In a breakthrough in the understanding of how cancer spreads, researchers at the University of Virginia School of Medicine have identified a substance secreted by lung cancer cells that enables them to metastasize, beginning their deadly march to other sites in the body.

10 Feb 2015

IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

The alarming increase of antibiotic-resistant bacteria poses health and economic threats worldwide, with more than 2 million Americans infected by the bacteria each year. Now, a team of Indiana University chemists and biologists has been awarded a major grant to develop and use a chemical tagging method to better understand how bacteria build their cell wall, which is still the best target for new antibiotics.

10 Feb 2015

Researchers discover inherited genetic variations associated with treatment-related hearing loss

St. Jude Children's Research Hospital investigators have discovered inherited genetic variations that are associated with rapid hearing loss in young cancer patients treated with the drug cisplatin. The research appears in the current online issue of the scientific journal Nature Genetics.

10 Feb 2015

Study links previously unknown genetic anomalies to breast cancer in African American family members

The "Jewels in our Genes" study, led by University at Buffalo researcher Heather Ochs-Balcom, has uncovered previously unknown segments of DNA shared by African American family members who have breast cancer. "The discovery of these regions supports our hypothesis that there are still undiscovered breast cancer genes that may be unique to African Americans," says Ochs-Balcom, PhD, a genetic epidemiologist in the UB Department of Epidemiology and Environmental Health.

10 Feb 2015

Cancer researchers find important clues to why tumor cells become 'good' or 'bad'

For the first time, Keck Medicine of the University of Southern California cancer researchers have traced the origins of colorectal cancer cells, finding important clues to why tumor cells become "good" or "bad," with the potential of stopping them before they start.

10 Feb 2015

Combination therapies may overcome resistance to targeted cancer drugs

A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies, according to a new study led by UC San Francisco researchers.

10 Feb 2015

New report raises ethical questions surrounding the use of data

Public participation should be at the heart of big data projects in health care and biomedical research, according to the findings of a new report by the Nuffield Council on Bioethics.

9 Feb 2015

Leading medical societies jointly release new statement on using carrier screening in reproductive medicine

Carrier screening for inherited genetic disorders is an important part of preconception and prenatal care for the nearly 4 million women who give birth in the US annually. Carrier screening is meant to identify couples at risk for passing on such genetic conditions to their children.

9 Feb 2015

Fungal infections rarely develop resistance to combination drug therapy

Researchers at the University of Toronto have discovered that Candida albicans -- a leading cause of potentially fatal hospital-acquired infections -- rarely develops resistance to combination drug therapy and, when it becomes resistant, it also becomes less dangerous.

9 Feb 2015

Personalized prevention, treatments of cancer now accessible through Stanford University's new genetics course

Instrumental research that aims to enhance how we predict, diagnose and design personalized prevention and treatments of cancer is now accessible through Stanford University's latest professional education course, Understanding Cancer at the Genetic Level.

9 Feb 2015

Researchers identify genetic variants associated with psoriatic arthritis

PsA is a common form of inflammatory form of arthritis causing pain and stiffness in joints and tendons that can lead to joint damage. Nearly all patients with PsA also have skin psoriasis and, in many cases, the skin disease is present before the arthritis develops. However, only one third of patients with psoriasis will go on to develop PsA.

5 Feb 2015

Study reports high rate of chromosomal abnormalities in patients in whom NIPT fails to provide results

In a study to be presented on Feb. 6 in an oral concurrent session at 1:15 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the high rate of chromosomal abnormalities in patients in whom noninvasive prenatal testing fails to provide results.

5 Feb 2015

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

There are two types of thyroid cells and therefore there are two broad types of thyroid cancer. Medullary carcinoma is derived from parafollicular or C cells, whereas follicular cells give rise to several types of thyroid cancers.

4 Feb 2015

Parents can pass silenced genes to offspring through a specific mechanism

For more than a century, scientists have understood the basics of inheritance: if good genes help parents survive and reproduce, the parents pass those genes along to their offspring. And yet, recent research has shown that reality is much more complex: genes can be switched off, or silenced, in response to the environment or other factors, and sometimes these changes can be passed from one generation to the next.

4 Feb 2015

23andMe announces publication of genome-wide association study of motion sickness

23andMe, Inc., the leading personal genetics company, today announced the publication of the first ever genome-wide association study of motion sickness.

4 Feb 2015

New study sheds light on syndrome linked to aggressive pediatric cancer

A new study involving researchers at The University of Nottingham has revealed how children with an aggressive cancer predisposition syndrome experience a never before seen flood of mutations in their disease in just six months.

4 Feb 2015

OGT study explores successful adoption of CytoSure ISCA array at Sheffield Children's NHS Foundation Trust

Oxford Gene Technology, The Molecular Genetics Company, explores how Sheffield Children's NHS Foundation Trust has seamlessly transferred to its CytoSure ISCA 8x60k platform, in a new case study entitled Evaluating and switching to CytoSure microarrays. As the result of a highly stringent National Health Service tender for the supply of oligo-based cytogenetics research arrays, CytoSure was selected based on the quality of data and analysis software.

From Oxford Gene Technology 4 Feb 2015

Amgen's biosimilar Phase 3 rheumatoid arthritis study meets primary and secondary endpoints

Amgen today announced a Phase 3 study evaluating the efficacy and safety of biosimilar candidate ABP 501 compared with Humira® (adalimumab) in patients with moderate-to-severe rheumatoid arthritis met its primary and key secondary endpoints.

4 Feb 2015

MGH, MIT researchers reveal how the brain controls different sleep states

Researchers at Massachusetts General Hospital and Massachusetts Institute of Technology have added another piece to the complex puzzle of how the brain controls one of the most essential functions - sleep.

4 Feb 2015

Scientists find eight different types of schizophrenia

Scientists from the universities of Granada (Spain) and Washington in St Louis (US) have found that there is not a single type of schizophrenia, but that it consists of a group made up of eight genetically different types of diseases, each of which presents its own set of symptoms.

4 Feb 2015

Genetics News and Research

Latest Genetics News and Research

Discovery leads to new understanding of cancer metastasis

IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

Researchers discover inherited genetic variations associated with treatment-related hearing loss

Study links previously unknown genetic anomalies to breast cancer in African American family members

Cancer researchers find important clues to why tumor cells become 'good' or 'bad'

Combination therapies may overcome resistance to targeted cancer drugs

New report raises ethical questions surrounding the use of data

Leading medical societies jointly release new statement on using carrier screening in reproductive medicine

Fungal infections rarely develop resistance to combination drug therapy

Personalized prevention, treatments of cancer now accessible through Stanford University's new genetics course

Researchers identify genetic variants associated with psoriatic arthritis

Study reports high rate of chromosomal abnormalities in patients in whom NIPT fails to provide results

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

Parents can pass silenced genes to offspring through a specific mechanism

23andMe announces publication of genome-wide association study of motion sickness

New study sheds light on syndrome linked to aggressive pediatric cancer

OGT study explores successful adoption of CytoSure ISCA array at Sheffield Children's NHS Foundation Trust

Amgen's biosimilar Phase 3 rheumatoid arthritis study meets primary and secondary endpoints

MGH, MIT researchers reveal how the brain controls different sleep states

Scientists find eight different types of schizophrenia

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging