Genetics News and Research

Latest Genetics News and Research

USC, Las Encinas Hospital to study on schizophrenia, bipolar disorder in younger, older adults

Schizophrenia and bipolar disorder affect 3% to 4% of the world's population, or about 222 million adults worldwide. In the United States, bipolar disorder affects about 5.7 million adult Americans 18 and older. Bipolar disorder, or manic depression, is a serious brain disorder that causes extreme shifts in mood, energy and functioning. People with the disorder experience episodes of mania and depression that can last from days to months. These symptoms usually begin in late adolescence, but can begin in early childhood or as late as a person's 40s or 50s. There is a strong genetic component related to bipolar disorder.

28 Sep 2010

Michael J. Fox Foundation launches PPMI clinical study to identify Parkinson's disease biomarkers

The Michael J. Fox Foundation has launched the Parkinson's Progression Markers Initiative (PPMI), the first ever large scale clinical study exclusively focused on identifying and validating Parkinson's disease biomarkers.

28 Sep 2010

Genomics obtains worldwide rights to The Garvan Institute of Medical Research's methylation DNA biomarkers

Clinical Genomics Pty. Ltd (Sydney, Australia) and The Garvan Institute of Medical Research (Sydney, Australia) today announced that they have entered into a license agreement in relation to novel biomarkers discovered by scientists at the Garvan Institute. Under the terms of the agreement, Clinical Genomics obtains worldwide exclusive rights to the Garvan's proprietary cancer associated methylation DNA biomarkers for the diagnosis and or treatment of colorectal cancer.

28 Sep 2010

Celiac disease on the rise in adults: Study

According to a new study published Monday in the Annals of Medicine, cases of intestinal disorder known as Celiac disease are on the rise with many adults developing the disease.

28 Sep 2010

BCBC awards $5 million for cell therapy research in type 1 diabetes

Maike Sander, MD, associate professor of pediatrics and cellular & molecular medicine at the University of California, San Diego School of Medicine has been awarded nearly $5 million by the Beta Cell Biology Consortium (BCBC) to lead an interdisciplinary team in cell therapy research for type 1 diabetes.

28 Sep 2010

Study finds increasing number of elderly people are prone to celiac diseases

Working to solve the puzzle of when people develop celiac disease has led researchers from the University of Maryland School of Medicine Center for Celiac Research to some surprising findings. They have found that the autoimmune disorder is on the rise with evidence of increasing cases in the elderly.

27 Sep 2010

Takeda announces SGN-35 ADC trial results in Hodgkin lymphoma patients

Seattle Genetics, Inc. and Millennium: The Takeda Oncology Company, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, today announced positive top line results from the pivotal trial of single agent brentuximab vedotin (SGN-35), an antibody drug conjugate (ADC) targeted to CD30. The trial was conducted in 102 relapsed or refractory Hodgkin lymphoma (HL) patients.

27 Sep 2010

Disparities in cardiac care begin when patients arrive at hospital emergency rooms: Study

The well-documented disparities in cardiac care may begin almost as soon as patients arrive at hospital emergency rooms. In a study published in Academic Emergency Medicine, Massachusetts General Hospital researchers report that African-American and Hispanic patients assessed for chest pain were less likely than white patients to be categorized as requiring immediate care, despite a lack of significant differences in symptoms.

27 Sep 2010

Researchers find no correlation between genetic ancestry and cancer stage

Head and neck cancer outcomes associated with race may be more closely linked to social and behavioral factors than biological differences, especially for African Americans, according to a new Henry Ford Hospital study.

27 Sep 2010

Alzheimer's treatments may prove effective if started in middle-aged people: Study

Memory lapses that occur with normal aging are a source of worry for many who fear Alzheimer's disease. Now a new Mayo Clinic-led study published in the July 16 issue of the New England Journal of Medicine suggests that the carriers of a common genetic risk factor for Alzheimer's disease begin to have memory declines in their mid-50s, far earlier than previously thought.

27 Sep 2010

Gene alteration impacts brain tumor development: Study

The interaction between a network of altered genes appears to play an important role in the development and progression of brain tumors, according to a study in the July 15 issue of JAMA.

27 Sep 2010

Enobia announces positive results from ENB-0040 Phase II juvenile clinical trial for hypophosphatasia

Enobia Pharma today announced positive results for its Phase II juvenile clinical trial of ENB-0040 (asfotase alfa), an experimental bone-targeted enzyme replacement therapy intended for the treatment of hypophosphatasia (HPP). Hypophosphatasia is a rare, inherited, and sometimes fatal metabolic bone disease that affects individuals of all ages.

24 Sep 2010

MTHFD1L gene may increase risk of developing late-onset Alzheimer's disease

Researchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer's disease, the most common form of the disease. The gene, abbreviated as MTHFD1L, is on chromosome six, and was identified in a genome-wide association study.

24 Sep 2010

Past exposure to pathogens leads to disease resistance spreading through populations

A study by researchers at Royal Holloway, University of London, University College London and Oxford University, has found that a genetic variant which reduces the chance of contracting diseases such as tuberculosis and leprosy is more prevalent in populations with long histories of urban living.

24 Sep 2010

Belfer Institute, sanofi-aventis collaborate to discover anticancer drugs

Dana-Farber Cancer Institute's Belfer Institute of Applied Cancer Science (Belfer Institute) and sanofi-aventis announced today that they have entered into a collaboration and license option agreement to identify and validate novel oncology targets for further discovery and development by sanofi-aventis of novel therapeutics agents directed to such targets and related biomarkers.

24 Sep 2010

Asthma linked to seven genetic variants: Study

In a new study seven genes linked to asthma have been discovered. For the research genetic variations of 10,365 people with asthma and 16,110 people without the condition was studied. The variants identified showed an association with childhood asthma and some were also associated with later-onset asthma.

24 Sep 2010

Boehringer Ingelheim, Eurofins Medigenomix partner in DNA banking and pharmacogenetics, pharmacogenomics

Boehringer Ingelheim Pharma GmbH & Co. KG, an international research-driven pharma company, and Eurofins Medigenomix GmbH, a competence center for genetic analyses of the Eurofins Scientific Group, concluded a long-term service agreement in the area of DNA banking, as well as a master service agreement for pharmacogenetic and pharmacogenomic services. For DNA banking Eurofins Medigenomix is supporting operations of Boehringer Ingelheim's central DNA bank at Biberach an der Riss.

23 Sep 2010

Interleukin Genetics announces clinical study data on osteoarthritis progression

Interleukin Genetics, Inc. and the Thurston Arthritis Research Center at the University of North Carolina at Chapel Hill announced today findings from a large clinical study to evaluate the role of genetic factors in osteoarthritis progression which showed patients with radiographic evidence of knee osteoarthritis who inherited a specific pattern of genetic variations in the interleukin-1 receptor antagonist (IL-1Ra) gene were almost twice as likely to progress to severe disease as other patients.

23 Sep 2010

Genetic variation in taste pathway genes associated with dental caries risk

Dental caries is a highly prevalent disease that is disproportionately distributed in the population. Caries occurrence and progression is known to be influenced by a complex interplay of both environmental and genetic factors, with numerous contributing factors having been identified including bacterial flora, dietary habits, fluoride exposure, oral hygiene, salivary flow, salivary composition, and tooth structure. Previous reports have characterized the influence of the genetic variation on taste preferences and dietary habits.

23 Sep 2010

Revolutionary technology 'cooks' brain tumor

University Hospitals (UH) Case Medical Center is offering new hope for patients with inoperable brain tumors or lesions previously diagnosed as untreatable through a revolutionary technology called AutoLITT which "cooks" brain tumors with an MRI-guided laser. UH becomes one of only three medical centers in the world offering AutoLITT as part of its arsenal in the fight against cancer. It is especially effective in treating glioblastoma, one of the most aggressive and difficult-to-treat brain cancers.

23 Sep 2010

Genetics News and Research

Latest Genetics News and Research

USC, Las Encinas Hospital to study on schizophrenia, bipolar disorder in younger, older adults

Michael J. Fox Foundation launches PPMI clinical study to identify Parkinson's disease biomarkers

Genomics obtains worldwide rights to The Garvan Institute of Medical Research's methylation DNA biomarkers

Celiac disease on the rise in adults: Study

BCBC awards $5 million for cell therapy research in type 1 diabetes

Study finds increasing number of elderly people are prone to celiac diseases

Takeda announces SGN-35 ADC trial results in Hodgkin lymphoma patients

Disparities in cardiac care begin when patients arrive at hospital emergency rooms: Study

Researchers find no correlation between genetic ancestry and cancer stage

Alzheimer's treatments may prove effective if started in middle-aged people: Study

Gene alteration impacts brain tumor development: Study

Enobia announces positive results from ENB-0040 Phase II juvenile clinical trial for hypophosphatasia

MTHFD1L gene may increase risk of developing late-onset Alzheimer's disease

Past exposure to pathogens leads to disease resistance spreading through populations

Belfer Institute, sanofi-aventis collaborate to discover anticancer drugs

Asthma linked to seven genetic variants: Study

Boehringer Ingelheim, Eurofins Medigenomix partner in DNA banking and pharmacogenetics, pharmacogenomics

Interleukin Genetics announces clinical study data on osteoarthritis progression

Genetic variation in taste pathway genes associated with dental caries risk

Revolutionary technology 'cooks' brain tumor

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging