Genetics News and Research

Latest Genetics News and Research

Abnormal "editing" of gene messages may cause Lupus

Researchers at Wake Forest University have uncovered evidence that the abnormal "editing" of gene messages in a type of white blood cell may be behind the development of lupus. Scientists hope the finding will lead to earlier diagnosis, a way to monitor patients' response to therapy and possibly a new way to treat the disease.

19 May 2008

Mapping of prostate cancer genes opens the door to new treatments

Genetic changes during the initiation and progression of prostate cancer have eluded scientists to date. Now for the first time researchers have identified a specific gene expression profile of prostate cancer stem cells, with important implications for future treatments.

19 May 2008

An improved gene therapy agent from University of Florida

Replacing one amino acid on the surface of a virus that shepherds corrective genes into cells could be the breakthrough scientists have needed to make gene therapy a more viable option for treating genetic diseases such as hemophilia, University of Florida researchers say.

19 May 2008

Reliable genetic tests could predict lung cancer recurrence

The goal of developing reliable genetic tests to guide lung cancer treatment has taken a step forward. Researchers at Columbia University recently evaluated the ability of five high-risk genetic profiles, or signatures, to predict the likelihood that cancer would recur in patients whose non-small cell lung cancer was caught early and surgically removed.

19 May 2008

Blood test for lung cancer

A simple blood test may be able to detect lung cancer in its earliest stages with unprecedented accuracy, according to new research to be presented at American Thoracic Society's 2008 International Conference in Toronto on Tuesday, May 20.

19 May 2008

NIH launches undiagnosed diseases program

The National Institutes of Health (NIH) today announced a new clinical research program that will aim to provide answers to patients with mysterious conditions that have long eluded diagnosis. Called the Undiagnosed Diseases Program, the trans-NIH initiative will focus on the most puzzling medical cases referred to the NIH Clinical Center in Bethesda, Md., by physicians across the nation.

19 May 2008

Rochester vaccine triggers immune response, prevents Alzheimer's

A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimer's disease-like pathology in mice without causing inflammation or significant side effects.

19 May 2008

Genes may control risk of contracting deadly skin cancer

A study carried out by an international team of scientists has revealed that a person's genes may control their risk of contracting a deadly skin cancer.

19 May 2008

A transgenic monkey model of Huntington's disease developed

Scientists have developed the first genetically altered monkey model that replicates some symptoms observed in patients with Huntington's disease, according to a new study funded by the National Institutes of Health. Researchers are now able to better understand this complex, devastating and incurable genetic disorder affecting the brain.

19 May 2008

deCODE discovers novel genetic links between pigmentation traits and risk of skin cancer

In two papers published today, deCODE scientists and academic colleagues from Europe and the U.S. expand upon the company's recent findings in the genetics of pigmentation traits in people of European descent, and demonstrate that certain of these common variants also confer risk of two types of skin cancer.

19 May 2008

Study implicates 350 gene regions in cancer development in the mouse

A large genetic study in mice has identified hundreds of genes involved in the development of cancer by examining the DNA of more than 500 lymphomas to find the cancer causing mutations.

15 May 2008

Discovery of 250 new genes potentially involved in leukemia

Researchers have found over 250 new genes that are potentially involved in the development of leukemia. The research was performed in close collaboration between the Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital (Amsterdam, The Netherlands) and the Wellcome Trust Institute (Cambridge, UK) and will be published in the Friday May 16th issue of the scientific journal Cell.

15 May 2008

Australian scientists use gene technology to improve IVF treatment

Research by a team of Australian scientists promises to improve the fertility treatment in vitro fertilisation (IVF).

15 May 2008

Molecular clock could predict risk for developing breast cancer

A chemical reaction in genes that control breast cancer provides a molecular clock that could one day help researchers more accurately determine a woman's risk for developing breast cancer and provide a new approach for treatment, UT Southwestern Medical Center researchers have found.

15 May 2008

Vitamin D protects cells from stress that can lead to cancer

By inducing a specific gene to increase expression of a key enzyme, vitamin D protects healthy prostate cells from the damage and injuries that can lead to cancer, University of Rochester Medical Center researchers report.

13 May 2008

A possible cure for pre-eclampsia

A condition which affects one in every ten pregnancies and is responsible for 1,000 baby deaths in Britain each year may have a genetic cause.

13 May 2008

Arsenic-based agent shown to help eradicate leukemia-initiating cells

In both leukemia and solid tumors, there exists among the multitude of warrior cancer cells a small subgroup that work undercover, patiently lying in wait to launch their attacks. Known as either cancer initiating cells (CICs) or leukemia initiating cells (LICs), these stealth populations are impervious to conventional chemotherapy and undaunted by targeted cancer therapies. When a leukemia patient relapses following a period of remission, it is the LICs that bear responsibility for the disease's reemergence.

12 May 2008

Scientists identify heat sensing regulator - better understanding pain sensitivity

Neuroscientists at Johns Hopkins are a step closer to understanding pain sensitivity - specifically why it's variable instead of constant - having identified a gene that regulates a heat-activated molecular sensor.

12 May 2008

How embryonic stem cells develop into tissue-specific cells demonstrated by researchers

While it has long been known that embryonic stem cells have the ability to develop into any kind of tissue-specific cells, the exact mechanism as to how this occurs has heretofore not been demonstrated.

12 May 2008

Molecular pathway in muscle helps explain effectiveness of diabetes interventions

Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), demonstrate for the first time in a mouse model that skeletal muscle cells cultured in a low-calorie environment refrain from differentiating, an energy-demanding process by which cells mature and specialize.

12 May 2008