Immunotherapy News and Research

Latest Immunotherapy News and Research

Researchers elucidate how ovarian tumors defy immunotherapy

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health, with collaborators at La Jolla Institute for Immunology and elsewhere, have further elucidated how ovarian cancer tumors defy immunotherapy, identifying new molecular targets that might boost immune response.

12 Apr 2022

Novel strategy can shrink tumors and prolong survival in mice

A research team based at the University of Ottawa and The Ottawa Hospital has developed a virus that infects and kills cancer cells without harming normal cells, while also sending out signals to prepare nearby uninfected cancer cells for viral attack.

11 Apr 2022

Adding immunotherapy to chemotherapy before surgery improves outcomes for NSCLC patients

Adding the immunotherapy drug nivolumab to chemotherapy before surgery (neoadjuvant) for patients with operable non-small cell lung cancer (NSCLC) — the leading cause of cancer deaths worldwide — reduced the risk of recurrence of the cancer or death by more than one-third, according to results from the phase III CheckMate-816 trial.

11 Apr 2022

Shared gene expression signatures in type 1 diabetics treated with IL-2 and COVID-19 patients

Researchers assess the impact of interval administration of LD-IL-2 was examined in 18 T1D patients who received a three-day dosing interval.

10 Apr 2022

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

A variant of the CTLA-4 gene associated with autoimmune disease was found to be more frequent in non-small cell lung cancer (NSCLC) patients who experienced an exceptionally high response to anti-PD-1 immunotherapy and higher immune-related side effects than in a comparable cohort of lung cancer patients and healthy individuals, according to data presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

NK cells complexed with bispecific antibody elicit high response rate in patients with resistant lymphomas

Natural killer (NK) cells derived from cord blood that were activated and complexed with a CD30/CD16A bispecific antibody elicited an 89 percent overall response rate in patients with relapsed or refractory CD30+ lymphoma, according to results from a phase I/II clinical trial presented at the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

Patients with non-small cell lung cancer (NSCLC) treated with the KRAS G12C inhibitor sotorasib (Lumakras) had a two-year overall survival rate of 32.5 percent, according to data from the CodeBreaK 100 clinical trial presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma

Patients with advanced melanoma whose cancer does not respond to treatment with widely used immunotherapy drugs known as PD-1 inhibitors are often switched to treatment with a second type of immunotherapy drug – a CTLA-4 inhibitor such as the drug ipilimumab.

8 Apr 2022

City of Hope's late-breaking clinical trial data to be presented at AACR

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, will present late-breaking and clinical trial findings at this year's American Association for Cancer Research Annual Meeting, which begins today.

8 Apr 2022

Unique immune cell fingerprint can help rapidly identify better treatment for autoimmune disease

Most autoimmune diseases are easy to diagnose but hard to treat. A paper published today in Science proposes using your unique immune cell fingerprint to rapidly identify which treatments will work for your autoimmune disease.

7 Apr 2022

Creation of immunosuppressive environment is key to the progression of colorectal cancer development

Interactions between cells of the immune system and pre-cancerous cells are known to be important contributing factors to the initiation and progression of cancer.

7 Apr 2022

Study to investigate new microbial-derived biomarkers for early detection of lung cancer

Dr Annalicia Vaughan from the Centenary UTS Centre for Inflammation is the successful recipient of the Kenyon Foundation Inflammation Award for 2022.

6 Apr 2022

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

New clinical research shows that lamivudine, a reverse transcriptase inhibitor widely used in HIV therapy, stopped disease progression in 25% of patients with fourth-line metastatic colorectal cancer.

5 Apr 2022

Health and Social Care Secretary announces an extension on the cancer call for evidence to April 8

More people can share their experiences and views on how the country can lead the world on cancer care, as the Health and Social Care Secretary announces an extension on the cancer call for evidence to inform an ambitious 10-Year Cancer Plan.

1 Apr 2022

Penn researchers generate functional CAR T cells with enhanced anti-tumor potency in 24 hours

A new approach from Penn Medicine researchers could cut the time it takes to alter patients' immune cells for infusion back into the body to find and attack cancer.

29 Mar 2022

Magneto-activated natural killer cells for treating solid tumors

Cancer immunotherapy - a type of treatment that enlists our own immune cells to attack tumors - has revolutionized the way that many types of cancer are treated. One type of immunotherapy under investigation uses natural killer cells, a type of immune cell that can seek and destroy harmful cells.

28 Mar 2022

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

Adding an anti-inflammatory medication to immunotherapy and standard chemotherapy drugs may provide long-term suppression of aggressive bladder tumor growth, according to a proof-of-concept study led by Cedars-Sinai Cancer investigators.

28 Mar 2022

New, potential treatment combination for patients with aggressive head and neck cancer

The current treatment of patients diagnosed with advanced or metastatic head and neck cancer (HNC) is ineffective.

28 Mar 2022

New trial examines the effectiveness of a two-pronged immunotherapy for glioblastomas

A new clinical trial at the University of Cincinnati is studying the effectiveness of a new two-pronged immunotherapy treatment procedure to treat the most aggressive and deadly type of brain tumors, called glioblastomas. Originating from healthy brain cells, glioblastomas can form in any area of the brain.

25 Mar 2022

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

23 Mar 2022

Immunotherapy News and Research

Latest Immunotherapy News and Research

Researchers elucidate how ovarian tumors defy immunotherapy

Novel strategy can shrink tumors and prolong survival in mice

Adding immunotherapy to chemotherapy before surgery improves outcomes for NSCLC patients

Shared gene expression signatures in type 1 diabetics treated with IL-2 and COVID-19 patients

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

NK cells complexed with bispecific antibody elicit high response rate in patients with resistant lymphomas

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma

City of Hope's late-breaking clinical trial data to be presented at AACR

Unique immune cell fingerprint can help rapidly identify better treatment for autoimmune disease

Creation of immunosuppressive environment is key to the progression of colorectal cancer development

Study to investigate new microbial-derived biomarkers for early detection of lung cancer

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

Health and Social Care Secretary announces an extension on the cancer call for evidence to April 8

Penn researchers generate functional CAR T cells with enhanced anti-tumor potency in 24 hours

Magneto-activated natural killer cells for treating solid tumors

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

New, potential treatment combination for patients with aggressive head and neck cancer

New trial examines the effectiveness of a two-pronged immunotherapy for glioblastomas

New therapy makes immunologically 'cold' tumors hot enough for immune attack

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Immunotherapy News and Research

Latest Immunotherapy News and Research

Event guide: 7th Allogeneic Cell Therapies Summit eBook

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

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