Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A new review initially described the developments in cancer-based medicines that included vaccinations, vector-based techniques, and genome injection using DNA and RNA-based nucleic acid therapeutics.

28 Apr 2022

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make the cancer vulnerable.

28 Apr 2022

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

A plant virus that infects legumes, called cowpea mosaic virus, has a special power that you may not have known about: when injected into a tumor, it triggers the immune system to treat the cancer - even metastatic cancer - and prevents it from recurring.

27 Apr 2022

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

The development of the anti-cancer immunotherapy drugs called immune checkpoint inhibitors has improved treatment for many cancer patients, but patients with mucosal melanomas - melanomas that occur not on the skin but in the mucous membranes in the head, neck, eyes, respiratory tract, and genitourinary region - are particularly resistant to immune checkpoint inhibitors for reasons researchers don't fully understand.

25 Apr 2022

New data may change the standard of care for patients with advanced non-small cell lung cancer

The phase 2 clinical trial of a multi-center study known as the COAST clinical trial has demonstrated improved outcomes using immunotherapy combinations for patients with unresectable stage III non-small cell lung cancer, according to researchers at Yale Cancer Center and participating organizations.

25 Apr 2022

Researchers test an experimental treatment for metastatic cancer

Researchers at the University of Oklahoma are testing an experimental treatment for metastatic cancer focusing on pancreatic cancer.

20 Apr 2022

CryoEM reveals never-before-seen details of the human androgen receptor

Scientists at Memorial Sloan Kettering Cancer Center (MSK) have glimpsed never-before-seen details of the human androgen receptor - the protein inside of cells that responds to male-typical hormones like testosterone.

20 Apr 2022

Newly discovered immune cell "soldier" could be a good target for immunotherapy

Despite the success of immunotherapy in helping many people with cancer, the majority of patients still do not respond to these treatments. There is need for continued research.

20 Apr 2022

CAR T-Cell Therapy: The Future of Cancer and HIV Treatment?

In this interview, News-Medical speaks to Professor Jun Huang about CAR T-cell therapy and its future as a potential treatment for cancer or HIV.

20 Apr 2022

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

20 Apr 2022

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly.

18 Apr 2022

Noninvasive sound technology could lead to improved cancer outcomes in humans

Noninvasive sound technology developed at the University of Michigan breaks down liver tumors in rats, kills cancer cells and spurs the immune system to prevent further spread—an advance that could lead to improved cancer outcomes in humans.

18 Apr 2022

A comprehensive rule book for the design of safe and efficient therapeutic cells

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

15 Apr 2022

Breakthrough finding reveals how male sex hormones contribute to cancer-related sex bias

Patients with cancers stemming from non-reproductive organs, such as bladder and liver cancer, have striking discrepancies in incidence, progression, response to treatment and survival outcomes depending on their sex. In almost all cases, male patients have worse prognoses and outcomes.

15 Apr 2022

Novel transdermal vaccine delivery for COVID-19 and cancer

Researchers assess the efficacy of a fluorocarbon modified chitosan system for the development of SARS-CoV-2 vaccines and tumor immunotherapy.

13 Apr 2022

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

Researchers at Mayo Clinic's Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors.

13 Apr 2022

A kind of kiss between cells plays key role in the fight between immune system and blood cancer cells

Researchers at The Ottawa Hospital and the University of Ottawa have discovered that a kind of kiss between cells, called trogocytosis, plays a key role in the battle between the immune system and blood cancer cells.

13 Apr 2022

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Acute lymphoblastic leukemia (ALL) cells from patients whose cancers did not respond to CD19-targeted CAR T therapy had gene regulation signatures that could potentially facilitate treatment resistance, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

13 Apr 2022

New bioinformatics platform predicts optimal treatment combinations for cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have developed a new bioinformatics platform that predicts optimal treatment combinations for a given group of patients based on co-occurring tumor alterations.

12 Apr 2022

New COVID-19 vaccine induces T-cell immune responses in most patients with B-cell deficiencies

CoVac-1, a new vaccine against SARS-CoV-2, induced T-cell immune responses in 93 percent of patients with B-cell deficiencies, including many patients with leukemia and lymphoma, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

12 Apr 2022

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

New data may change the standard of care for patients with advanced non-small cell lung cancer

Researchers test an experimental treatment for metastatic cancer

CryoEM reveals never-before-seen details of the human androgen receptor

Newly discovered immune cell "soldier" could be a good target for immunotherapy

CAR T-Cell Therapy: The Future of Cancer and HIV Treatment?

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Noninvasive sound technology could lead to improved cancer outcomes in humans

A comprehensive rule book for the design of safe and efficient therapeutic cells

Breakthrough finding reveals how male sex hormones contribute to cancer-related sex bias

Novel transdermal vaccine delivery for COVID-19 and cancer

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

A kind of kiss between cells plays key role in the fight between immune system and blood cancer cells

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

New bioinformatics platform predicts optimal treatment combinations for cancer patients

New COVID-19 vaccine induces T-cell immune responses in most patients with B-cell deficiencies

Event guide: 7th Allogeneic Cell Therapies Summit eBook

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Immunotherapy News and Research

Latest Immunotherapy News and Research

Event guide: 7th Allogeneic Cell Therapies Summit eBook

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Newsletters you may be interested in