Metabolism News and Research

Latest Metabolism News and Research

CTSI licenses GeneGo's pathway analysis suite and database searching tool

GeneGo, Inc., a leading provider of software and databases for systems biology, today announced that the Indiana Clinical and Translational Sciences Institute has licensed its pathway analysis suite MetaCore and its database searching tool Eureka.

23 Mar 2010

Researchers investigate link between consumption of high-fructose corn syrup and obesity

A Princeton University research team has demonstrated that all sweeteners are not equal when it comes to weight gain: Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same.

23 Mar 2010

Novo Nordisk Foundation donates $160M to University of Copenhagen for metabolic research

The Center will conduct research into Type 2 diabetes, among other diseases, and will acquire the capacities and resources to establish itself as one of the leading international research centers in the world. With 885 million Danish kroner (approx. 160 million US Dollars) from the Novo Nordisk Foundation, a team of 5 leading research scientists will be headhunted by the University to oversee "The Novo Nordisk Foundation Center for Basic Metabolic Research".

From Novo Nordisk 23 Mar 2010

Walnuts affect genes related to prostate tumor growth: Study

Walnut consumption slows the growth of prostate cancer in mice and has beneficial effects on multiple genes related to the control of tumor growth and metabolism, UC Davis and the U.S. Department of Agriculture Western Regional Research Center in Albany, Calif. have found.

23 Mar 2010

Legacy Biotechnologies, Phillips Sales and Marketing reach agreement to distribute Reme-Flu remedy

Nuvilex, Inc., announces today that Legacy Biotechnologies, Inc., its joint venture partner in Reme-Flu™ homeopathic flu remedy, has reached an agreement with Phillips Sales and Marketing to begin the national sales and marketing campaign for retail distribution of Reme-Flu™.

22 Mar 2010

High dose of Zocor could lead to muscle injury, warns FDA

The U.S. Food and Drug Administration today warned patients and healthcare providers about the potential for increased risk of muscle injury from the cholesterol-lowering medication Zocor (simvastatin) 80 mg.

20 Mar 2010

A.P. Pharma's NDA for APF530 in prevention of CINV: FDA issues Complete Response Letter

A.P. Pharma, Inc., a specialty pharmaceutical company, today announced that it received a Complete Response Letter from the U.S. Food and Drug Administration regarding its New Drug Application for APF530 in the prevention of both acute and delayed onset chemotherapy-induced nausea and vomiting.

19 Mar 2010

Legacy Biotechnologies commences production of Reme-Flu

Nuvilex, Inc., announces today that Legacy Biotechnologies, Inc., its joint venture partner in Reme-Flu™, has commenced production of Reme-Flu™ and expects it to be ready for consumer purchase within the next 30 days. Reme-Flu™ is Legacy Biotechnologies’ unique 2-part homeopathic flu remedy designed to help treat symptoms of the flu. Initially, Reme-Flu™ will be offered on the top-rated website, www.nutralegacy.com.

18 Mar 2010

USPTO allows Regulus Therapeutics' claims covering methods of antagonizing miR-181a for regulating immune response

Regulus Therapeutics Inc. announced today that the United States Patent and Trademark Office (USPTO) has allowed claims in U.S. Application Serial No. 11/977,506 covering methods of antagonizing miR-181a to regulate immune response. This patent is owned by Stanford University and licensed exclusively to Regulus. miR-181a has been shown to regulate the response of immune cells, such as T lymphocytes, to specific stimuli and modulation of miR-181a could lead to a novel treatment of inflammatory disease.

18 Mar 2010

Having lower TSH levels while taking thyroxine replacement is not detrimental to health, says study

New research shows that it may be safe for patients taking thyroxine replacement to have low but not suppressed thyroid stimulating hormone (TSH) levels. The research, presented at the Society for Endocrinology BES meeting in Manchester, shows for the first time that it may be safe for patients to take slightly higher doses of thyroxine than are currently recommended.

18 Mar 2010

LSUHSC: Differences in drug metabolism can lead to differences in the effectiveness of candidate drug

Research led by Wayne L. Backes, PhD, Professor of Pharmacology and Associate Dean for Research at LSU Health Sciences Center New Orleans School of Medicine, has found that drug metabolism depends not only upon which enzymes are present in an individual, but also how they interact, and that can be the difference in whether a drug is safely eliminated from the body or is converted into a toxic or carcinogenic byproduct.

18 Mar 2010

High plasma selenium concentrations linked to lower occurrence of dysglycemia in elderly men

The role of selenium in diabetes has been controversial, with some studies suggesting that it raises diabetes risk and others finding that it is protective. Now, research published in BioMed Central's open access journal Nutrition and Metabolism, has shown that, for men, high plasma selenium concentrations are associated with a lower occurrence of dysglycemia.

18 Mar 2010

PAREXEL genotypes over 10,000 potential study participants to identify 400 CYP2D6 poor metabolizers

PAREXEL International Corporation, a leading global biopharmaceutical services provider, today announced that it has completed a large and complex pharmacogenetics-based early phase study. The study was conducted in a healthy volunteer population of poor metabolizers of Cytochrome P450 2D6 (CYP2D6), an important enzyme involved in the metabolism of drugs. The study monitored the QTc interval following administration of a neurological treatment, which has been shown to have a higher drug exposure in poor metabolizers of CYP2D6.

From Parexel 17 Mar 2010

Low-impact, weight-bearing exercise does not affect bone density during weight loss

While there are many benefits of losing weight, weight reduction also might negatively affect bones in the body. During weight loss, bones are being remodeled - breaking down old bone and forming new bone - at an accelerated rate.

17 Mar 2010

Pathway Genomics' personal Genetic Health Report now available

Pathway Genomics Inc., a U.S. based genetic testing company, announced the immediate availability of its personal Genetic Health Report. This customized and innovative personal genetic health report contains information on more than 70 health conditions, including pharmacogenetics (prescription medication response), propensity for complex disease, and carrier status (pre-pregnancy health).

17 Mar 2010

Anti-obesity drugs fail to tackle wider issues of obesity

Scientists at the University of Liverpool argue that anti-obesity drugs fail to provide lasting benefits for health and wellbeing because they tackle the biological consequences of obesity, and not the important psychological causes of overconsumption and weight gain.

17 Mar 2010

Obesity and passive smoking are risk factors for elevated umbilical cord neonatal immature

Babies born to mothers with obesity and exposed to passive smoking are more likely to have health problems than others. This conclusion is based on evidence of elevated levels of nucleated red blood cells in the umbilical cord reported in the International Journal of Food Safety, Nutrition and Public Health.

17 Mar 2010

Lantheus Medical Imaging announces preliminary data on flurpiridaz F 18 PET MPI agent

Lantheus Medical Imaging, Inc., a worldwide leader in diagnostic imaging, today announced preliminary data on flurpiridaz F 18 (formerly known as BMS747158), its novel compound in development as a Positron Emission Tomography (PET) myocardial perfusion imaging (MPI) agent. The study of nine patients compared rest-stress flurpiridaz F 18 PET MPI, with rest-stress technetium-99m (Tc-99m) labeled single photon emission computed tomography (SPECT) for the detection and evaluation of coronary artery disease (CAD).

16 Mar 2010

Vitamin D supplements might do more harm than good for African-American patients

Vitamin D is quickly becoming the "go-to" remedy for treating a wide range of illnesses, from osteoporosis to atherosclerosis. However, new evidence from a Wake Forest University School of Medicine study suggests that supplementing vitamin D in those with low levels may have different effects based on patient race and, in black individuals, the supplement could actually do harm.

16 Mar 2010

Roche Diagnostics named sole source supplier for Premier's blood glucose monitoring devices

Roche Diagnostics announced today that it has been awarded contracts for blood glucose monitoring and clinical chemistry/immunoassay lab analyzers from Premier Purchasing Partners, L.P., Inc., the group purchasing unit of Premier, Inc. Roche was also named the sole source supplier for blood glucose in Premier's exclusive ASCEND supply chain performance program.

From Roche Sequencing and Life Science 16 Mar 2010

Metabolism News and Research

Latest Metabolism News and Research

CTSI licenses GeneGo's pathway analysis suite and database searching tool

Researchers investigate link between consumption of high-fructose corn syrup and obesity

Novo Nordisk Foundation donates $160M to University of Copenhagen for metabolic research

Walnuts affect genes related to prostate tumor growth: Study

Legacy Biotechnologies, Phillips Sales and Marketing reach agreement to distribute Reme-Flu remedy

High dose of Zocor could lead to muscle injury, warns FDA

A.P. Pharma's NDA for APF530 in prevention of CINV: FDA issues Complete Response Letter

Legacy Biotechnologies commences production of Reme-Flu

USPTO allows Regulus Therapeutics' claims covering methods of antagonizing miR-181a for regulating immune response

Having lower TSH levels while taking thyroxine replacement is not detrimental to health, says study

LSUHSC: Differences in drug metabolism can lead to differences in the effectiveness of candidate drug

High plasma selenium concentrations linked to lower occurrence of dysglycemia in elderly men

PAREXEL genotypes over 10,000 potential study participants to identify 400 CYP2D6 poor metabolizers

Low-impact, weight-bearing exercise does not affect bone density during weight loss

Pathway Genomics' personal Genetic Health Report now available

Anti-obesity drugs fail to tackle wider issues of obesity

Obesity and passive smoking are risk factors for elevated umbilical cord neonatal immature

Lantheus Medical Imaging announces preliminary data on flurpiridaz F 18 PET MPI agent

Vitamin D supplements might do more harm than good for African-American patients

Roche Diagnostics named sole source supplier for Premier's blood glucose monitoring devices

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut