Metabolomics

Metabolomics is a field of research that focuses on the chemical processes undergone by metabolites. It involves the use of sophisticated analytical technologies to identify and quantify cellular metabolites, in addition to the extraction of relevant information so that the data can be interpreted and applied in a practical setting.

Applications of Metabolomics

The field of metabolomics has the potential to be applied in a number of settings to offer practical use. It remains a relatively young field of research and, therefore many of its applications of metabolomics are still only becoming evident. Nonetheless, this article covers some of the present and future ways in which metabolomics could be applied.

Metabolic Changes in Aging Cells

Lipid Metabolism and the Gut Microbiota

Metabolomics in Clinical Chemistry

Metabolomics in Organ Transplantation

Metabolomics in Plants

Metabolomic Profiling for Disease Diagnosis

Challenges in Targeted Metabolomics

Metabolomic Profiling of Ricin

History of Metabolomics

Metabolomics in Pharmacology

The Metabolome: An Overview

See more featured articles »

Analyzing Metabolomics Data

What are Metabolites?

Techniques Used in Targeted Metabolomic Profiling

Targeted Metabolomics

Metabolomic Profiling of an Ancient Herbal Medicine using UHPLC

Latest Metabolomics News and Research

Carrot fiber supplement boosts gut bacteria and immune defenses

This trial reveals that carrot-derived rhamnogalacturonan-I boosts Bifidobacteria and supports immune function, highlighting its potential for gut health.

18 Sep 2025

Can changing food texture reduce how much we eat? Dutch study investigates

A new randomized controlled trial protocol from the Netherlands will test whether altering the texture, and thus the eating rate, of ultra-processed foods can reduce daily energy intake. The study will investigate how sensory properties, such as food hardness, affect metabolism, appetite, and microbiome composition.

16 Sep 2025

Female-specific mechanism enhances heat production in brown fat

Higher activity of PGC-1α enables brown fat cells in females to thermogenic activity and energy expenditure compared to males, reveals a study conducted in Japan.

12 Sep 2025

Roasted Arabica coffee hides powerful antidiabetic molecules

Three novel coffee diterpene esters, caffaldehydes A, B, and C, were discovered in Arabica beans, showcasing significant alpha-glucosidase inhibitory activity.

3 Sep 2025

Glycosylation emerges as a key player in kidney disease progression

Kidney diseases affect nearly 700 million people worldwide and are a growing cause of mortality and health care costs.

29 Aug 2025

Can the gut microbiome adapt to protect the brain after stroke?

Alterations in gut microbiota post-stroke may drive metabolic changes, presenting opportunities for innovative therapeutic strategies in acute stroke recovery.

28 Aug 2025

Mediterranean diet lowers dementia risk by altering key metabolites

Researchers linked genetics, plasma metabolites, and Mediterranean diet adherence to dementia risk in two large US cohorts, showing APOE4 homozygotes had distinct metabolic pathways. Diet-related metabolites mediated protection, highlighting precision-prevention opportunities.

26 Aug 2025

Can diet alone slow brain aging? Scientists say evidence is still too weak

Researchers reviewing evidence in the Annual Review of Nutrition find that healthy dietary patterns may support brain aging, but caution that scientific enthusiasm currently outpaces solid proof. Multidomain strategies combining diet with exercise, cognitive training, and vascular health show greater promise.

25 Aug 2025

Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk

A new study led by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard suggests that a Mediterranean-style diet may help reduce dementia risk.

25 Aug 2025

How a single gene reshapes pain perception through polyamine signaling

Researchers have identified SLC45A4 as a neuronal polyamine transporter genetically linked to human chronic pain. Loss of this gene in mice disrupts polyamine balance, alters spinal GABA levels, and reduces heat and tonic pain sensitivity.

24 Aug 2025

New method enables comprehensive analysis of metabolites in biological samples

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

AI predicts designer drug structures for improved detection

How does one identify something no one has a test for? Designer drugs replicate the effects of known, illicit drugs but evade law enforcement. The chemical structure variations that help these compounds avoid detection also make them unpredictable in the body - a quality that poses serious health consequences.

21 Aug 2025

Fish oil supplementation can reduce risk of developing type 2 diabetes in prediabetic individuals

Type 2 diabetes (T2D) has become one of the leading chronic diseases worldwide in terms of both incidence and mortality.

20 Aug 2025

Red meat consumption disrupts gut bacteria and worsens colonic inflammation

Epidemiological studies have revealed a strong correlation between red meat consumption and the development of inflammatory bowel disease.

20 Aug 2025

New strategies to tackle resistant foodborne pathogens

Innovative approaches in food and beverage analysis are transforming pathogen detection and control, emphasizing the role of natural compounds and sequencing.

19 Aug 2025

FastUKB transforms UK Biobank research with seamless data extraction and analysis

FastUKB is an innovative tool specifically developed to streamline and enhance research workflows utilizing the UK Biobank, effectively addressing key limitations of existing platforms such as the UK Biobank Research Analysis Platform (RAP).

18 Aug 2025

Mitochondrial metabolite glutathione plays key role in breast cancer metastasis

The mitochondria may be the powerhouse of the cell, but mounting evidence suggests this organelle is also a driving force behind cancer.

18 Aug 2025

Newly discovered drug class could someday lead to breakthrough treatments for fungal infections

A research team at McMaster University has discovered a new drug class that could someday lead to breakthrough treatments for dangerous fungal infections.

11 Aug 2025

How too much screen time affects kids’ heart health and what can reduce the risk

A large Danish cohort study found that higher screen time in childhood and adolescence is linked to worse cardiometabolic health, with shorter sleep amplifying the risk. Blood metabolomics revealed a signature of high screen time, and in teens, it was tied to higher predicted cardiovascular disease risk.

7 Aug 2025

Personalizing endometrial cancer prevention through diet and lifestyle

This review synthesizes emerging evidence on modifiable risk factors for endometrial cancer (EC)-the sixth most common female malignancy globally-with rising incidence despite diagnostic advances.

7 Aug 2025