Metabolomics

Metabolomics is a field of research that focuses on the chemical processes undergone by metabolites. It involves the use of sophisticated analytical technologies to identify and quantify cellular metabolites, in addition to the extraction of relevant information so that the data can be interpreted and applied in a practical setting.

Applications of Metabolomics

The field of metabolomics has the potential to be applied in a number of settings to offer practical use. It remains a relatively young field of research and, therefore many of its applications of metabolomics are still only becoming evident. Nonetheless, this article covers some of the present and future ways in which metabolomics could be applied.

What are Metabolites?

History of Metabolomics

Analyzing Metabolomics Data

Targeted Metabolomics

Metabolomics in Plants

Challenges in Targeted Metabolomics

The Metabolome: An Overview

Metabolomics in Organ Transplantation

Metabolomics in Clinical Chemistry

Metabolomics in Pharmacology

Metabolic Changes in Aging Cells

See more featured articles »

Metabolomic Profiling for Disease Diagnosis

Techniques Used in Targeted Metabolomic Profiling

Metabolomic Profiling of an Ancient Herbal Medicine using UHPLC

Metabolomic Profiling of Ricin

Lipid Metabolism and the Gut Microbiota

Latest Metabolomics News and Research

NMR Metabolomics as Novel Screening Tool for New-borns (For Research Only)

In this interview, Oscar Millet, group leader of the Precision Medicine and Metabolism group of the CIC bioGUNE, talked to News Medical about his research into the use of nuclear magnetic resonance spectroscopy (NMR) metabolomic analysis as a clinical screening tool. His team has used NMR to screen urine samples form new-borns for congenital metabolic disorders.

From Bruker BioSpin - NMR, EPR and Imaging 20 Oct 2020

Serum metabolite profile can help identify individuals at risk of alcohol-related disease

A new study from the University of Eastern Finland is the first in the world to show that the serum metabolite profile can be used to identify individuals likely at risk of developing an alcohol-related disease in the future.

19 Oct 2020

New machine learning concepts can help develop novel drugs

Tandem mass spectrometry is a powerful analytical tool used to characterize complex mixtures in drug discovery and other fields.

14 Oct 2020

Too little sugar is the cause of perforated bones

Bone marrow cancer is currently an incurable disease that affects about 400 people in Norway every year. Professor Therese Standal at NTNU has now found an important reason for bone destruction in people with this disease.

9 Oct 2020

UCLA researchers receive $13 million NIH grant to combat melanoma

UCLA researchers have received a $13 million grant from the National Institutes of Health to find new ways to overcome melanoma resistance to some of the most promising targeted therapies and immunotherapies.

28 Sep 2020

New framework allows researchers to probe the metabolic processes inside cancer cells

One of the biggest challenges to the development of medical treatments for cancer is the fact that there is no single kind of cancer.

28 Sep 2020

NAU researcher awarded $3.75 million NCI grant to build cancer research software

Greg Caporaso, director of the Center for Applied Microbiome Science, part of the Pathogen and Microbiome Institute at Northern Arizona University, has been awarded a $3.75 million grant by the National Cancer Institute to build software capable of analyzing and archiving data focused on the interplay between the human microbiome (the trillions of microorganisms living in and on the human body) and diverse types of cancer.

22 Sep 2020

Heat and gut microbiota promote stronger bones

Osteoporosis, a bone disease linked to ageing, is characterized by a loss of bone density, micro-architectural deterioration of the bones and an increased risk of fractures.

11 Sep 2020

Exploring the Relationship Between Mass Spectrometry and Informatics

Mass spectrometry has always had a powerful synergy with computers. Computers have pushed mass spectrometry forward at key junctures in it’s history from data collection to instrument operation to data analysis.

From Bruker Daltonics 9 Sep 2020

Study illuminates the role of body temperature in realizing diet-induced health benefits

Cutting calories significantly may not be an easy task for most, but it's tied to a host of health benefits ranging from longer lifespan to a much lower chance of developing cancer, heart disease, diabetes and neurodegenerative conditions such as Alzheimer's.

8 Sep 2020

Simple urine test could speed up adrenal cancer diagnosis

Using a simple urine test alongside routine imaging for patients with adrenal masses could speed up adrenal cancer diagnosis, improving patient's prognosis and reducing the need for invasive diagnostic procedures, a new multi-centre study published in The Lancet Diabetes & Endocrinology has found.

23 Jul 2020

Novel biomarkers for diagnosis of ureteropelvic junction obstruction in infants

One in every 500 babies is born with a condition called ureteropelvic junction obstruction (UPJO), an obstruction of the ureter that prevents urine from flowing from one or both of the kidneys into the bladder.

22 Jul 2020

Deep Longevity and Human Longevity announce collaboration to deploy AI-powered aging clocks

Today, Deep Longevity Inc, a developer of deep biomarkers of human aging, and Human Longevity Inc announce a collaboration to deploy an extensive range of AI-powered aging clocks.

14 Jul 2020

Untargeted metabolomics can determine genetic variant to improve patient diagnosis

A patient and family walk into a doctor's office. They hope that the latest tests will reveal what is causing the patient's illness and end the diagnostic odyssey they have been going through for years.

8 Jul 2020

Modern mass spectrometry applications in research

Bentham Science Publishers have recently published a new book series on mass spectrometry applications, in research.

6 Jul 2020

Researchers discover marine alga from Kiel Fjord as potential remedy against infections, skin cancer

Healing with the help of marine organisms is no utopia. Already 12 life-saving drugs, e.g. against cancer, have been developed from marine organisms and their symbiotic microbiota.

2 Jul 2020

Blood cell damage in COVID-19 may compromise oxygen transport

Researchers in the U.S. have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may alter key protein structures on red blood cells and compromise the transport and delivery of oxygen in patients with coronavirus disease 2019 (COVID-19).

1 Jul 2020

Stool microbial and metabolite signatures predict cirrhosis

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide, affecting an estimated one-quarter of the global population. It is a progressive condition that, in worst cases, can lead to cirrhosis, liver cancer, liver failure and death.

30 Jun 2020

The gut shields the liver from fructose-induced lipogenesis

After one consumes food or a beverage containing fructose, the gastrointestinal system, or gut, helps to shield the liver from damage by breaking down the sugar before it reaches the liver, according to a new multi-center study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

29 Jun 2020

A metabolomics approach to detect objective biomarkers of ASD

In a paper published online this week in Autism Research, scientists at NeuroPointDX, a division of Stemina Biomarker Discovery, Inc., in collaboration with researchers at the UC Davis MIND Institute and academic and clinical institutions across the country, report new findings from the Children's Autism Metabolome Project or CAMP.

18 Jun 2020