Metabolomics

Metabolomics is a field of research that focuses on the chemical processes undergone by metabolites. It involves the use of sophisticated analytical technologies to identify and quantify cellular metabolites, in addition to the extraction of relevant information so that the data can be interpreted and applied in a practical setting.

Applications of Metabolomics

The field of metabolomics has the potential to be applied in a number of settings to offer practical use. It remains a relatively young field of research and, therefore many of its applications of metabolomics are still only becoming evident. Nonetheless, this article covers some of the present and future ways in which metabolomics could be applied.

What are Metabolites?

History of Metabolomics

Analyzing Metabolomics Data

Targeted Metabolomics

Metabolomics in Plants

Challenges in Targeted Metabolomics

The Metabolome: An Overview

Metabolomics in Organ Transplantation

Metabolomics in Clinical Chemistry

Metabolomics in Pharmacology

Metabolic Changes in Aging Cells

See more featured articles »

Metabolomic Profiling for Disease Diagnosis

Techniques Used in Targeted Metabolomic Profiling

Metabolomic Profiling of an Ancient Herbal Medicine using UHPLC

Metabolomic Profiling of Ricin

Lipid Metabolism and the Gut Microbiota

Latest Metabolomics News and Research

Size of tumor tissue area crucial for reliable cancer prognosis, study shows

The method of choice used for preparing tissue samples can lead to biased results in the analysis of cancer patient survival.

27 Mar 2020

Computer program analyzes blood plasma to identify weight gain biomarkers

Researchers at the University of Campinas in São Paulo State, Brazil, have developed a computer program that analyzes molecules in blood plasma to search for biomarkers that identify individuals who are at risk of becoming overweight and developing obesity-related diseases.

10 Mar 2020

New tool shows potential to predict developmental toxicity in humans with high accuracy

Recently published results from an evaluation of 1,065 chemical and drug substances using the devTOX quickPredict (devTOXqP) screening platform developed by Stemina Biomarker Discovery, Inc. demonstrated the platform's ability to predict developmental toxicity in humans with high accuracy using a cell-based test.

3 Mar 2020

Johns Hopkins researchers make progress in the development of noninvasive urine test for prostate cancer

Researchers at the Johns Hopkins Kimmel Cancer Center have made significant progress toward development of a simple, noninvasive liquid biopsy test that detects prostate cancer from RNA and other specific metabolic chemicals in the urine.

28 Feb 2020

Reduced stress associated with changes in plasma metabolite profile

Reduced stress is linked to changes in the profile of plasma metabolites, a new study from the University of Eastern Finland shows.

25 Feb 2020

Autophagy genes work against tumors in some ovarian cancers

Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina and University of California at San Diego published findings in PLOS Genetics this month showing that autophagy or "self-eating" genes work against tumors in certain types of ovarian cancer.

13 Feb 2020

Targeting the microenvironment of cancer cells to inhibit tumor growth

The recognition of bacterial infections or foreign substances is mediated and controlled by the human immune system. This innate and adaptive immune system comprises the most important metabolic and cellulare processes to fight against infections and other diseases.

5 Feb 2020

New way to classify pituitary tumors could lead to better diagnoses

Houston Methodist neurosurgeons and neuroscientists are looking at a new way to classify pituitary tumors that could lead to more precise and accurate diagnosing for patients in the future.

4 Feb 2020

High-fiber diet can reverse adverse effects of environmental toxins on cardiovascular health

Research from the University of Kentucky's Superfund Research Center (UK-SRC) shows that a diet high in fiber could possibly reverse the adverse effects that environmental toxins have on cardiovascular health.

30 Jan 2020

Holistic and data-driven health assessment can help achieve early disease detection

Human Longevity, Inc., an innovator in providing data-driven health intelligence and precision health to physicians and patients, announced today the publication of a ground-breaking study in the journal Proceedings of the National Academy of Sciences.

27 Jan 2020

PET/MRI identifies potentially useful breast cancer biomarkers

Researchers have identified several potentially useful breast cancer biomarkers that indicate the presence and risk of malignancy, according to new research published in the January issue of The Journal of Nuclear Medicine.

22 Jan 2020

Persistant industrial chemical modifies gut microbiome of mice

An industrial chemical -- phased out since 2002, but previously used in stain and water-repellent products and firefighting foam -- alters the gut microbiome of mice and could have implications for human health, according to an international team of researchers.

21 Jan 2020

UT Southwestern researchers explain racial disparities in heart failure risk

Researchers at UT Southwestern have uncovered evidence that the higher prevalence of "malignant" enlargement of the heart among blacks contributes to the higher incidence of heart failure in this population.

14 Jan 2020

How SpatialOMx is Delivering New Insights into Disease Research

An interview with Shannon Cornett Ph.D, discussing the use of MALDI-guided spatial molecular analysis for biomarker discovery.

From Bruker Daltonics 14 Jan 2020

Study of glycobiology and glycan diagnostics in personalized medicine featured in OMICS special issue

An in-depth look at the science of glycobiology and glycan diagnostics, and their promise in personalized medicine in the current post-genomic era are featured in a special issue of OMICS: A Journal of Integrative Biology, the peer-reviewed interdisciplinary journal published by Mary Ann Liebert, Inc., publishers.

13 Jan 2020

Evolutionary adaptations may lead to different microbial populations, shows study

It's no secret there's a close relationship between humans and our microbiomes -- the communities of microbes that live in and on us.

7 Jan 2020

Connection between herpes virus and Alzheimer’s refuted

A new study has shown that unlike previous claims, there is no association between getting herpes infections and developing Alzheimer’s disease. The study from the researchers at the Baylor College of Medicine was titled, “Are HHV-6A and HHV-7 really more abundant in Alzheimer’s disease?” and was published in the journal Neuron.

19 Dec 2019

Study refutes link between increased levels of herpes virus and Alzheimer's disease

Researchers at Baylor College of Medicine report today in the journal Neuron evidence that refutes the link between increased levels of herpes virus and Alzheimer's disease.

18 Dec 2019

Pittcon 2020 Short Course Registration Now Open

Pittcon is pleased to announce its 2020 Short Course continuing education program, which includes the addition of nearly 20 new courses. Registration for the Short Course program, offered at Pittcon 2020 in Chicago, IL, February 29 - March 5, is now open.

From Pittcon 11 Dec 2019

CSU awarded $1.2 million subcontract to accelerate tuberculosis vaccine development

A team of researchers in the Department of Microbiology, Immunology and Pathology at Colorado State University aim to advance what is known about the complex immune response necessary to prevent tuberculosis disease.

15 Nov 2019