Metabolomics

Metabolomics is a field of research that focuses on the chemical processes undergone by metabolites. It involves the use of sophisticated analytical technologies to identify and quantify cellular metabolites, in addition to the extraction of relevant information so that the data can be interpreted and applied in a practical setting.

Applications of Metabolomics

The field of metabolomics has the potential to be applied in a number of settings to offer practical use. It remains a relatively young field of research and, therefore many of its applications of metabolomics are still only becoming evident. Nonetheless, this article covers some of the present and future ways in which metabolomics could be applied.

What are Metabolites?

History of Metabolomics

Analyzing Metabolomics Data

Targeted Metabolomics

Metabolomics in Plants

Challenges in Targeted Metabolomics

The Metabolome: An Overview

Metabolomics in Organ Transplantation

Metabolomics in Clinical Chemistry

Metabolomics in Pharmacology

Metabolic Changes in Aging Cells

See more featured articles »

Metabolomic Profiling for Disease Diagnosis

Techniques Used in Targeted Metabolomic Profiling

Metabolomic Profiling of an Ancient Herbal Medicine using UHPLC

Metabolomic Profiling of Ricin

Lipid Metabolism and the Gut Microbiota

Latest Metabolomics News and Research

Child with Bachmann-Bupp Syndrome successfully treated in just 16 months

Diagnosing a rare medical condition is difficult. Identifying a treatment for it can take years of trial and error. In a serendipitous intersection of research expertise, an ill patient in this case a child and innovative technology, Bachmann-Bupp Syndrome has gone from a list of symptoms to a successful treatment in just 16 months.

20 Jul 2021

Metabolomics: The Individual Metabolic Profile is the Key to Personalized Medicine

The study of these unique substances in each of us paves the way for a revolution in the treatment and prevention of diseases, allowing for early diagnosis and increasingly targeted pharmacological treatments.

From Bruker BioSpin - NMR, EPR and Imaging 14 Jul 2021

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

The National Institutes of Health has awarded the University of South Florida total expected funds of $69.9 million over the next four years to continue the follow-up of study participants in The Environmental Determinants of Diabetes in The Young (TEDDY) consortium.

13 Jul 2021

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

A team led by researchers at Baylor College of Medicine found that a screening method known as untargeted metabolomics profiling can improve the diagnostic rate for inborn errors of metabolism, a group of rare genetic conditions, by about seven-fold when compared to the traditional metabolic screening approach.

12 Jul 2021

Can saliva metabolomics predict COVID-19 severity?

New research suggests that saliva metabolomics may be able to help prognosticate disease severity in COVID-19 positive individuals.

9 Jul 2021

Biomarker discovery can open door to screening newborn babies for pyridoxine-dependent epilepsy

The door has finally opened on screening newborn babies for pyridoxine-dependent epilepsy (PDE), a severe inherited metabolic disorder. This screening promises to enable better and earlier treatment of the disease.

8 Jul 2021

A new method for generating metabolic profiles of single cells

Scientists from the European Molecular Biology Laboratory and the German Cancer Research Center have presented a new method for generating metabolic profiles of individual cells.

6 Jul 2021

Metabolomics lab analysis reveals large nutritional differences between near-meat and meat

Plant-based meat substitutes taste and chew remarkably similar to real beef, and the 13 items listed on their nutrition labels - vitamins, fats and protein -- make them seem essentially equivalent.

6 Jul 2021

Study provides a reliable early prognostic biomarker for COVID-19 severity

In a retrospective, multi-centre cohort study conducted by researchers from Nanjing University, Huazhong University of Science and Technology, Jinling Hospital and the Second Hospital of Nanjing, a microRNA-like small RNA encoded by SARS-CoV-2 was identified in the serum of COVID-19 patients, which can be developed as a non-invasive biomarker for stratification of severe patients from mild/moderate ones and for identification of high-risk individuals before clinical manifestation of severe symptoms.

6 Jul 2021

World-first study uses artificial intelligence to map the risks of ovarian cancer in women

The University of South Australia will lead a world-first study, using artificial intelligence, to map the risks of the most fatal reproductive cancer in women worldwide so it can be detected and treated earlier.

2 Jul 2021

Genetic variants in a neuro-associated gene cause neurodevelopmental disorder, finds study

Mayo Clinic researchers have discovered that genetic variants in a neuro-associated gene called SPTBN1 are responsible for causing a neurodevelopmental disorder. The study, published in Nature Genetics, is a first step in finding a potential therapeutic strategy for this disorder, and it increases the number of genes known to be associated with conditions that affect how the brain functions.

2 Jul 2021

New biomarkers can predict HIV remission after antiretroviral therapy interruption

New biomarkers that predict HIV remission after antiretroviral therapy (ART) interruption are critical for the development of new therapeutic strategies that can achieve infection control without ART, a condition defined as functional cure.

29 Jun 2021

Nicotinamide can help stimulate plant immune systems, shows study

Fungal diseases in cereal crops cause major economic losses and also threaten human and livestock health, because some fungi produce powerful toxins that might enter the food chain. Farmers use fungicides to control crop diseases, such as wheat head blight. Although agrochemicals are rigorously tested for safety, there can be concerns over chemical residues in food.

11 Jun 2021

Systemic biomarkers show beneficial effects of aerobic exercise on brain function in older adults

Increasing evidence shows that physical activity and exercise training may delay or prevent the onset of Alzheimer's disease (AD). In aging humans, aerobic exercise training increases gray and white matter volume, enhances blood flow, and improves memory function.

10 Jun 2021

Study shows why COVID-19 has widely varying outcomes in different people

The answer is something infectious disease experts are working to uncover. As COVID-19 revealed, the same pathogen can have widely varying outcomes in different people.

7 Jun 2021

New process could reinvigorate the search for natural product drugs to treat cancers, viral infections

Researchers from Carnegie Mellon University's Computational Biology Department in the School of Computer Science have developed a new process that could reinvigorate the search for natural product drugs to treat cancers, viral infections and other ailments.

3 Jun 2021

New book brings the latest advances in gastroenterology and hepatology

Knowledge in medicine is a very dynamic process due to the continuing progress in this field. New developments influence research, but also the clinical practice. Hence the continuous need for improvement in the field in which we work is required.

29 May 2021

A potential treatment to prevent obesity-related liver damage

One of the especially dangerous health risks of being extremely overweight occurs when an obese person begins to accumulate fat in their liver.

18 May 2021

Korea's first large-scale project reaches milestone of sequencing 10,000 whole genomes

On April 26, UNIST and Ulsan City officially announced that their ambitious 10,000 Genome Project has finally reached the milestone of sequencing 10,000 whole genomes.

10 May 2021

SARS-CoV-2 infection prolongs viral shedding and lymphocyte loss in patients with cancer

Patients with cancer have a more challenging time with infections while undergoing treatment — placing them as high-risk for severe COVID-19 illness and death. However, how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with cancer therapies remains poorly understood.

7 May 2021