Metabolomics

Metabolomics is a field of research that focuses on the chemical processes undergone by metabolites. It involves the use of sophisticated analytical technologies to identify and quantify cellular metabolites, in addition to the extraction of relevant information so that the data can be interpreted and applied in a practical setting.

Applications of Metabolomics

The field of metabolomics has the potential to be applied in a number of settings to offer practical use. It remains a relatively young field of research and, therefore many of its applications of metabolomics are still only becoming evident. Nonetheless, this article covers some of the present and future ways in which metabolomics could be applied.

What are Metabolites?

History of Metabolomics

Analyzing Metabolomics Data

Targeted Metabolomics

Metabolomics in Plants

Challenges in Targeted Metabolomics

The Metabolome: An Overview

Metabolomics in Organ Transplantation

Metabolomics in Clinical Chemistry

Metabolomics in Pharmacology

Metabolic Changes in Aging Cells

See more featured articles »

Metabolomic Profiling for Disease Diagnosis

Techniques Used in Targeted Metabolomic Profiling

Metabolomic Profiling of an Ancient Herbal Medicine using UHPLC

Metabolomic Profiling of Ricin

Lipid Metabolism and the Gut Microbiota

Latest Metabolomics News and Research

What are the effects of pesticides on neonates' health?

A new study explores the impact of pesticide exposure in neonates, reviewing current literature while evaluating the research methods used in this area.

20 Sep 2022

Study supports the importance of healthy diet for better cognitive function across races, ethnicities

Dietary choices and their consequences may certainly influence cognitive function. A new study led by investigators at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, along with outside collaborators expands on previously published work (focused on Puerto Rican individuals in the U.S.) by including additional races and ethnicities.

16 Sep 2022

Metabolic signature could be a potential target for new breast cancer therapies

Despite advancements in cancer detection and treatment, breast cancer that comes back or spreads still presents a challenge to researchers and oncologists.

6 Sep 2022

How does the human gut microbiome impact menopause?

A recent study summarizes available information on the relationship between menopause and the gut microbiome.

24 Aug 2022

Fortified human breastmilk alters the microbiota of low-birth-weight infants

A new study discusses how fortified human milk changes the gut microbiome in these babies.

24 Aug 2022

New strategies to enhance the survival of children with neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN (MYCN amplified), the primary driver of neuroblastoma and its resistance to therapy.

18 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

Identifying a core human microbiome

Researchers provide a critical review of the concept of the core human microbiome.

19 Jul 2022

Evidence for a specific anti-inflammatory metabolic signature in long-COVID

A recent research paper posted to the medRxiv* preprint server illustrated anti-inflammatory and hypo-metabolic fingerprints in long coronavirus disease (COVID) syndrome (LCS) using pan-omics plasma assessments.

15 Jul 2022

Study reveals a specific metabolic adaptation in some patients with acute myeloid leukemia

An article published in the journal Nature Communications describes a specific metabolic adaptation in some patients with acute myeloid leukemia affected by tandem mutations in the FLT3 gene.

13 Jul 2022

How is the microbiome of an infant influenced by mother's bacteria?

A recent study explores the sources and functional importance of certain key species in the mother-infant transmission of the microbiota.

5 Jul 2022

New discovery could lead to more effective treatments for asthma sufferers

New research led by Edith Cowan University has made an important discovery that could lead to more effective treatments for the world's 262 million asthma sufferers.

4 Jul 2022

Using omics technology to characterize and quantify biomolecules for better nutrition

Maya Rajasekharan, Senior Advisor, Strategic Program Development at the Alliance of Bioversity International and the International Center for Tropical Agriculture (CIAT), says that food is the single greatest determinant of human health and disease over the course of one's life, and yet a comprehensive understanding of the composition of what we eat remains unknown.

22 Jun 2022

Scientists discover 15 additional genetic mutations linked to KCNK9 imprinting syndrome

A collaborative team of scientists led by Mayo Clinic's Center for Individualized Medicine has discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome.

21 Jun 2022

Five new studies shed light on the eating behaviors and diets of teens, young adults

The developmental changes and growing independence that characterize adolescence and young adulthood can make these stages of life both exciting and challenging.

14 Jun 2022

USA–Japan Workshop participants present cutting-edge research on biomarkers for early detection of cancer

Successful treatment of cancer frequently depends on early detection. However, many cancers are detected late, often after metastasizing to other sites.

9 Jun 2022

Diet rich in polyphenols can prevent inflammation in the elderly

Polyphenols in the foods that we eat can prevent inflammation in older people, since they alter the intestinal microbiota and induce the production of the indole 3-propionic acid (IPA), a metabolite derived from the degradation of tryptophan due to intestinal bacteria.

8 Jun 2022

The potential role of the gut microbiome in modifying patient responses to statin therapy

Researchers discovered strong links between human gut microbiome makeup and statin on- and off-target effects, probably beneficial in medication tailoring.

13 May 2022

Biomarkers in the blood can indicate the seriousness of head trauma

A simple blood sample to diagnose patients with traumatic brain injury - an innovation enabled by researchers at örebro University.

10 May 2022

Researchers reveal the mechanism of action of century-old BCG vaccine

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world's oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic TB, it has surprisingly been found to protect newborns and young infants against multiple bacterial and viral infections unrelated to TB. There's even some evidence that it can reduce severity of COVID-19.

4 May 2022