Multiple Myeloma

Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. These cells are part of your immune system, which helps protect the body from germs and other harmful substances. In time, myeloma cells collect in the bone marrow and in the solid parts of bone.

What is Multiple Myeloma?

Multiple myeloma is a form of cancer that affects the bone marrow. The cancer is also called Kahler’s disease, named after an Austrian pathologist called Otto Kahler who first described the condition.

Multiple Myeloma Diagnosis

Multiple Myeloma Pathophysiology

Multiple Myeloma Treatment

Multiple Myeloma Epidemiology

Multiple Myeloma Symptoms

Management of Myeloma

Multiple Myeloma Imaging Strategies

Latest Multiple Myeloma News and Research

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Dana-Farber Cancer Institute researchers will present more than 40 research studies at the virtual 62nd American Society of Hematology Annual Meeting on December 5-8, including two studies that were selected for inclusion in the official press program.

1 Dec 2020

Underrepresented minorities are at increased risk for AL amyloidosis

Despite being theoretically at an increased risk for AL amyloidosis, underrepresented minorities make up only a small percentage of patients seen at specialized treatment centers for this disease.

11 Nov 2020

Beat AML trial achieves primary endpoint

Patients participating in The Leukemia & Lymphoma Society's (LLS) groundbreaking precision medicine Beat AML Master Clinical Trial had superior outcomes compared to acute myeloid leukemia (AML) patients who opted for standard chemotherapy treatment, according to findings published today in the prestigious Nature Medicine journal.

28 Oct 2020

Advancements in research on cancer signal transduction and treatment

Cancer is driven by numerous genetic and epigenetic changes occurring at the cellular level. These changes drive normal cells to proliferate and escape processes that usually regulate their survival and migration.

27 Oct 2020

Radiation therapy before CART-BCMA appears to be a safe option for multiple myeloma patients

Administering radiation therapy to multiple myeloma patients waiting for CAR T cells to be manufactured was found to be safe and undisruptive to CAR T therapy, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania to be presented Tuesday, October 27, at the virtual American Society for Radiation Oncology Annual Meeting (Abstract #35562).

27 Oct 2020

Researchers are developing a new class of compounds against various cancers

Researchers at The Wistar Institute and collaborators from the University of Notre Dame are developing anticancer compounds targeting a pathway of the endoplasmic reticulum (ER) stress response implicated in the development of multiple myeloma (MM), chronic lymphocytic leukemia (CLL) and lymphoma.

14 Oct 2020

Challenges in High Complexity Flow Cytometry

The last decade has seen a revolution in cancer immunotherapy. The demand from doctors, researchers, and pharmaceutical companies for more precise results with high sensitivity and high-quality testing is increasing immensely.

From Beckman Coulter Life Sciences - Flow Cytometry 24 Sep 2020

Research uncovers potential cause of neurotoxicity due to immunotherapy

New research has uncovered the previously unknown presence of CD19 -- a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma -- in brain cells that protect the blood brain barrier (BBB).

21 Sep 2020

New partnership aims to advance predictive tests for multiple myeloma in Ireland

By combining genomic testing and next generation sequencing technology, a new partnership led by RCSI researchers aims to advance predictive tests for multiple myeloma, the second most common blood cancer in Ireland.

18 Sep 2020

Neil Bell appointed as Chief Development Officer of Avacta Life Sciences

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce the appointment of Neil Bell as Chief Development Officer of Avacta Life Sciences with immediate effect. Neil will be responsible for late stage pre-clinical and early clinical development of Avacta’s pipeline of pre|CISION pro-drugs and Affimer immunotherapies.

From Avacta Life Sciences Ltd. 13 Aug 2020

New alpha-radioimmunotherapy for multiple myeloma shows promise in preclinical study

A new alpha-radioimmunotherapy, 212Pb-anti-CD38, has proven effective in preventing tumor growth and increasing survival in multiple myeloma tumor-bearing mice, according to new research published in the July issue of the Journal of Nuclear Medicine. Given the long half-life, central production and worldwide distribution of 212Pb-anti-CD38, researchers have determined that the α-radioimmunotherapy is not only effective but also clinically feasible as a multiple myeloma treatment.

6 Aug 2020

Chemists discover a way to create synthetic version of natural anti-cancer compound

Scripps Research chemists Hans Renata, PhD, and Alexander Adibekian, PhD, have discovered a way to efficiently create a synthetic version of a valuable natural compound called cepafungin I, which has shown promise as an anti-cancer agent.

6 Aug 2020

Waterloo tech profiles antibodies in blood of COVID-19 patients

A world-leading University of Waterloo spinoff company, that decodes blood samples for potential treatments for illnesses like cancer and COVID-19, is expanding operations with the help of a $5-million USD investment.

29 Jul 2020

First CAR T-cell therapy for mantle cell lymphoma receives FDA approval

Today's Food and Drug Administration approval of the first CAR T-cell therapy for mantle cell lymphoma represents a key advance for patients with relapsed or treatment-resistant forms of the disease, say Dana-Farber Cancer Institute investigators who helped conduct the decisive clinical trial of the therapy.

24 Jul 2020

Fox Chase and BGU receive grant for cancer treatment study

Scientists at Fox Chase Cancer Center and Ben-Gurion University of the Negev (BGU) have received a new grant from the United States-Israel Binational Science Foundation (BSF) that will fund continuing research on an antibody developed as part of a longstanding collaboration between the two organizations.

17 Jul 2020

Stand Up To Cancer announces new effort to achieve health equity for underserved lung cancer patients

Stand Up To Cancer today announced a new $5 million grant from Bristol Myers Squibb to fund research and education efforts aimed at achieving health equity for underserved lung cancer patients, including Black people and people living in rural communities.

16 Jul 2020

New cancer vaccine shows promising signs in preclinical studies

Scientists are ready to trial a new cancer vaccine in humans following the successful outcome of their preclinical studies.

9 Jul 2020

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Activating the immune system of the body is a promising form of treatment for cancer. Researchers at the University of Helsinki and Helsinki University Hospital as well as the University of Eastern Finland mapped out the immune landscape of hematological malignancies in a dataset covering more than 10,000 patients to identify drug targets and patient groups which could potentially benefit from immunotherapies.

9 Jul 2020

Latest findings put Benson Viscometers at the forefront of Covid-19 fight

A clinical viscosity diagnostic instrument is proving to be valuable in the research and treatment of coronavirus after laboratory scientists have identified its ability to provide meaningful data for medical teams treating Covid-19 patients.

3 Jul 2020

Researchers receive innovative grants to understand the biological underpinnings of blood cancers

Seeking to ignite the next major breakthroughs to treat blood cancers, The Leukemia & Lymphoma Society (LLS), The Mark Foundation, and The Paul G. Allen Frontiers Group today announced more than $6.75 million awarded to nine of the most exceptional scientists in the field.

1 Jul 2020

Multiple Myeloma

Overview

Multiple Myeloma Diagnosis

Multiple Myeloma Pathophysiology

Multiple Myeloma Treatment

Feature Articles

Multiple Myeloma Epidemiology

Multiple Myeloma Symptoms

Management of Myeloma

Multiple Myeloma Imaging Strategies

Latest Multiple Myeloma News and Research

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Underrepresented minorities are at increased risk for AL amyloidosis

Beat AML trial achieves primary endpoint

Advancements in research on cancer signal transduction and treatment

Radiation therapy before CART-BCMA appears to be a safe option for multiple myeloma patients

Researchers are developing a new class of compounds against various cancers

Challenges in High Complexity Flow Cytometry

Research uncovers potential cause of neurotoxicity due to immunotherapy

New partnership aims to advance predictive tests for multiple myeloma in Ireland

Neil Bell appointed as Chief Development Officer of Avacta Life Sciences

New alpha-radioimmunotherapy for multiple myeloma shows promise in preclinical study

Chemists discover a way to create synthetic version of natural anti-cancer compound

Waterloo tech profiles antibodies in blood of COVID-19 patients

First CAR T-cell therapy for mantle cell lymphoma receives FDA approval

Fox Chase and BGU receive grant for cancer treatment study

Stand Up To Cancer announces new effort to achieve health equity for underserved lung cancer patients

New cancer vaccine shows promising signs in preclinical studies

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Latest findings put Benson Viscometers at the forefront of Covid-19 fight

Researchers receive innovative grants to understand the biological underpinnings of blood cancers

Could beta-blockers be a potential treatment for COVID-19?

The American Lung Association say to wear masks to stop the spread of COVID-19; Here’s why

The Prospects of Semaglutide for Treatment of Type 2 Diabetes Patients

Multiple Myeloma

Overview

Feature Articles

Multiple Myeloma Epidemiology

Multiple Myeloma Symptoms

Management of Myeloma

Multiple Myeloma Imaging Strategies

Latest Multiple Myeloma News and Research

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