Pain News and Research

Latest Pain News and Research

Clinical study shows association between Corus CAD blood test scores and cardiovascular event rates

CardioDx, Inc., a molecular diagnostics company specializing in cardiovascular genomics, announced today results from a genomic substudy of the NHLBI-funded Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial in nondiabetic patients receiving the Corus CAD blood test.

7 Apr 2016

3D MRE offers accurate non-invasive method to detect advanced fibrosis

Nonalcoholic fatty liver disease, or NAFLD, comprises a group of liver disorders whose prevalence is widespread and rising. It's estimated that at least one-third of Americans have NAFLD; among obese persons, the figure is 50 percent.

6 Apr 2016

Bariatric surgery improves pain, physical function in obese patients

Among a group of patients with severe obesity who underwent bariatric surgery, a large percentage experienced improvement in pain, physical function, and walking capacity over 3 years, according to a study appearing in the April 5 issue of JAMA.

6 Apr 2016

Inflectra (infliximab-dyyb) approved for multiple indications

The U.S. Food and Drug Administration today approved Inflectra (infliximab-dyyb) for multiple indications. Inflectra is administered by intravenous infusion. This is the second biosimilar approved by the FDA.

6 Apr 2016

$Ethnicity, socioeconomic status and place of residence influence risk of experiencing a fracture$

Ethnicity, socioeconomic status and place of residence influence risk of experiencing a fracture

Ethnicity, socioeconomic status and place of residence in the UK all influence the risk of breaking a bone, a new Southampton study has shown.

5 Apr 2016

New neurological mechanism can contribute to pain reduction

A UT Dallas scientist has found a new neurological mechanism that appears to contribute to a reduction in pain.

5 Apr 2016

Analysis reveals improved survivorship for acute liver failure patients

More patients hospitalized with acute liver failure - often the result of acetaminophen overdose - are surviving, including those who receive a liver transplant and those who don't, an analysis led by a UT Southwestern Medical Center researcher showed.

5 Apr 2016

New tool facilitates shared decision-making between physicians and patients with chest pain

Patients visiting a hospital emergency department with chest pain who engaged with their physician in shared decision-making using a tool called Chest Pain Choice showed improved knowledge of their health status and follow-up care options compared with patients who received standard counseling from a physician without the use of this decision aid, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

Electrical stimulation of deep brain structures to ease chronic pain

Abuse of prescription opioid medicines used to treat chronic pain has reached epidemic proportions, so much that the White House has announced new efforts to combat addiction and prevent the thousands of overdose-related deaths reported in the U.S. each year.

5 Apr 2016

Study: Disparities in pain management may be partly attributed to bias

Research has documented that black Americans are systematically undertreated for pain relative to white Americans, likely due to both the over-prescription and over-use of pain medications among white patients and the under-prescription of pain medications for black patients.

5 Apr 2016

Two established atrial fibrillation ablation techniques show similar effects, safety outcomes

Two established techniques for correcting the root cause of the heart rhythm disorder atrial fibrillation show similar effects and safety outcomes, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

Tests used for diagnosing heart disease appear to function differently for women and men

Tests used to diagnose and assess the severity of coronary artery disease appear to function differently for women and men who have stable symptoms, according to researchers from Duke Clinical Research Institute.

5 Apr 2016

Evolocumab could be more effective than ezetimibe in lowering cholesterol in statin-intolerant patients

In the first major trial of its kind, Cleveland Clinic researchers used a blinded rechallenge with atorvastatin or placebo to objectively confirm the presence of muscle-related symptoms in patients with a history of intolerance to multiple statins and found that evolocumab (a PCSK9 inhibitor) was a more effective option to lower cholesterol than ezetimibe in these patients.

4 Apr 2016

Patient-oriented tool helps shared decision-making between patients and physicians for chest pain

Patients who arrive at the emergency department with low-risk chest pain and talk through treatment options with a physician show improved knowledge of their health status and follow-up options, compared with patients who received standard counseling from a physician, according to Mayo Clinic research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Women who undergo uterine fibroid embolization experience improved sexual function

Women who underwent a nonsurgical, image-guided treatment, uterine fibroid embolization (UFE), for the treatment of uterine fibroids experienced improved sexual function and a higher overall quality of life. The research, part of a French multicenter study, presented at the Society of Interventional Radiology's Annual Scientific Meeting, also found the vast majority of women treated with UFE sustained improvement for more than a year.

4 Apr 2016

Researchers compare lipid-lowering efficacy for two nonstatin therapies in statin-intolerant patients

Steven E. Nissen, M.D., of the Cleveland Clinic, and colleagues identified patients with muscle-related adverse effects from statins and compared lipid-lowering efficacy for two nonstatin therapies, ezetimibe and evolocumab. The study was published online by JAMA, and is being released to coincide with its presentation at the American College of Cardiology's 65th Annual Scientific Session & Expo.

4 Apr 2016

Heart disease patients who experience mental stress ischemia tend to have higher levels of troponin

Some people with heart disease experience a restriction of blood flow to the heart in response to psychological stress. Usually silent (not painful), the temporary restriction in blood flow, called ischemia, is an indicator of greater mortality risk.

4 Apr 2016

Cholesterol drug evacetrapib fails to reduce risk of cardiovascular events

Despite lowering low-density lipoprotein (LDL), known as "bad" cholesterol, while markedly increasing levels of high-density lipoprotein (HDL), or "good" cholesterol, a large clinical trial to investigate the cholesterol drug evacetrapib was discontinued early after a preliminary analysis showed it did not reduce rates of major adverse cardiovascular events, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

NICE issues positive guidance on use of electroCore’s gammaCore treatment for migraine and cluster headache

The UK’s National Institute of Health and Care Excellence has published guidance that electroCore’s non-invasive vagus nerve stimulation treatment (gammaCore) for the prevention and acute treatment of migraine and cluster headache is safe and can now be used in the NHS.

4 Apr 2016

Researchers develop novel vaccine strategy to protect against Chikungunya virus

The Chikungunya virus (CHIKV) is transmitted through mosquitoes and causes fever and joint pain that can sometimes become severe and disabling. Outbreaks of the virus have already occurred in Africa, Asia, and Europe, and in late 2013, the virus was first seen in the Americas with the number of cases dramatically increased. No vaccine to prevent or treat this virus currently exists.

2 Apr 2016

Pain News and Research

Latest Pain News and Research

Clinical study shows association between Corus CAD blood test scores and cardiovascular event rates

3D MRE offers accurate non-invasive method to detect advanced fibrosis

Bariatric surgery improves pain, physical function in obese patients

Inflectra (infliximab-dyyb) approved for multiple indications

Ethnicity, socioeconomic status and place of residence influence risk of experiencing a fracture

New neurological mechanism can contribute to pain reduction

Analysis reveals improved survivorship for acute liver failure patients

New tool facilitates shared decision-making between physicians and patients with chest pain

Electrical stimulation of deep brain structures to ease chronic pain

Study: Disparities in pain management may be partly attributed to bias

Two established atrial fibrillation ablation techniques show similar effects, safety outcomes

Tests used for diagnosing heart disease appear to function differently for women and men

Evolocumab could be more effective than ezetimibe in lowering cholesterol in statin-intolerant patients

Patient-oriented tool helps shared decision-making between patients and physicians for chest pain

Women who undergo uterine fibroid embolization experience improved sexual function

Researchers compare lipid-lowering efficacy for two nonstatin therapies in statin-intolerant patients

Heart disease patients who experience mental stress ischemia tend to have higher levels of troponin

Cholesterol drug evacetrapib fails to reduce risk of cardiovascular events

NICE issues positive guidance on use of electroCore’s gammaCore treatment for migraine and cluster headache

Researchers develop novel vaccine strategy to protect against Chikungunya virus

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

Pain News and Research

Latest Pain News and Research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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