Pain

Using a Pain Diary

A pain diary to record chronic pain patterns and triggers can be useful to improve control of pain management.

Comparing Nociceptive and Neuropathic Pain

Pain in the Lower Right Abdomen: When to be Concerned

Antidepressants in Pain Management

Chronic Pain: The 20 Most Painful Conditions

Latest Pain News and Research

Fructans and ATIs impact digestive health in beer

The GLUTEN3S research group of the University of the Basque Country (EHU) has identified the presence of fructans and amylase/trypsin inhibitor (ATI) proteins in gluten-free beers made from barley, compounds that can cause digestive symptoms in sensitive individuals. Its content is comparable to that of traditional beers containing gluten, according to a study published in the Journal of Food Composition and Analysis.

16 Dec 2025

Hydrogel-based treatment achieves innervation and pulp-dentin regeneration

The dental pulp is susceptible to microbial infection, which often results in inflammation, necrosis, and defects in the pulp-dentin complex. Traditional treatment strategies suffer from multiple limitations and do not promote neural regeneration.

16 Dec 2025

Large-scale study to examine nail fungus impact on athletic performance

Athletes are 2.5 times more likely than the general public to develop nail fungus, according to a study in the Journal of the American Academy of Dermatology.

16 Dec 2025

Injury burden is higher during menstruation in professional female footballers

The menstrual cycle is a key physiological process in women: it impacts performance, neuromuscular control, metabolism, and immune response.

16 Dec 2025

One big beautiful bill act complicates state health care affordability efforts

As Congress debates whether to extend the temporary federal subsidies that have helped millions of Americans buy health coverage, a crucial underlying reality is sometimes overlooked: Those subsidies are merely a band-aid covering the often unaffordable cost of health care.

16 Dec 2025

Blood test identifies colon cancer patients who benefit from anti-inflammatory medication

A blood test could help doctors decide which patients with colon cancer should receive anti-inflammatory medication along with chemotherapy after surgery, according to new study in JAMA Oncology.

15 Dec 2025

Tiny blood particles help shuttle a hormone through the body

Researchers at Touro University Nevada have discovered that tiny particles in the blood, called extracellular vesicles (EVs), are a major player in how a group of hormones are shuttled through the body. Physical exercise can stimulate this process.

15 Dec 2025

Half of hospitalized COVID-19 patients developed long COVID

Research from Thailand shows high long COVID prevalence in hospitalized patients, with severe illness increasing risk and vaccination offering protection.

15 Dec 2025

Unnecessary gluten-free diets may put children at risk

Understanding gluten-related disorders is crucial for pediatric nutrition, as gluten-free diets can pose health risks without appropriate medical supervision.

15 Dec 2025

Cryo-EM reveals NPFFR1 activation and guides novel ligand design

This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1 (NPFFR1)-a Gi/o-coupled receptor that responds to endogenous RF-amide peptides (RFRP-3 from pro-NPFFB, NPFF from pro-NPFFA) and regulates physiological processes like opioid function, pain, and energy homeostasis.

13 Dec 2025

New CMS models could reshape the landscape for lifestyle medicine practice and reimbursement

The American College of Lifestyle Medicine (ACLM) applauds two new Centers for Medicare and Medicaid Services (CMS) models that could significantly reshape the landscape for lifestyle medicine practice and reimbursement.

12 Dec 2025

Etomidate proves safer than ketamine for emergency intubations

Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published Dec. 9 in the New England Journal of Medicine.

12 Dec 2025

SN101 iPSC-derived therapy relieves chronic pain and preserves joints

SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach to chronic pain management and joint tissue preservation.

12 Dec 2025

Interdisciplinary project aims reduce noise exposure for premature children in neonatal care

Premature babies are particularly susceptible to strong sensory impressions and high sound levels from the incubator. Now researchers will look at what can be done to protect children's hearing and development.

12 Dec 2025

Exclusive licensing agreement accelerates PHD inhibitor development for anemia in CKD patients

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and TaiGen Biotechnology, a listed discovery-based and market-focused pharmaceutical company, as well as TaiGen Biopharmaceuticals, its wholly-owned Beijing subsidiary (both referred to as "TaiGen"), today announced an exclusive pipeline out-licensing collaboration.

12 Dec 2025

AI-guided discovery of selective DGKα inhibitors to overcome checkpoint resistance in solid cancers

Insilico Medicine has developed a new class of small molecule inhibitors targeting diacylglycerol kinase alpha (DGKα) designed to restore T cell function and overcome resistance to immune checkpoint blockades in solid cancers.

12 Dec 2025

Maxillary nerve block may reduce perioperative opioid consumption in pediatric primary clefts

For infants undergoing cleft palate surgery, local anesthetic injection targeting the maxillary nerve of the face may reduce or eliminate the need for opioid medications to control postoperative pain, reports a study in The Journal of Craniofacial Surgery.

12 Dec 2025

Acupuncture improves breast cancer survivors' perceived cognitive impairment

Real and sham acupuncture were more effective at improving breast cancer survivors' perceived cognitive impairment compared with usual care, while real acupuncture was superior to sham acupuncture in improving objective cognitive function, according to results from the randomized ENHANCE phase II clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

12 Dec 2025

Mobile health intervention improves quality of life for adolescent and young adult breast cancer survivors

A mobile health (mHealth) intervention for adolescent and young adult breast cancer survivors that offered tailored support by monitoring electronic patient-reported outcomes (ePROs) significantly improved quality of life and symptoms related to vaginal and arm problems, according to results from a randomized clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

12 Dec 2025

Fear strongly influences pain perception in inflammatory bowel disease patients

Pain perception in affected individuals is more strongly influenced by learned fear than in healthy individuals. Changes along the gut-brain axis related to chronic inflammation may explain this.

12 Dec 2025