Pain

Using a Pain Diary

A pain diary to record chronic pain patterns and triggers can be useful to improve control of pain management.

Chronic Pain: The 20 Most Painful Conditions

Antidepressants in Pain Management

Comparing Nociceptive and Neuropathic Pain

Pain in the Lower Right Abdomen: When to be Concerned

Latest Pain News and Research

Insilico and SK Biopharmaceuticals partner to develop AI-driven neuroimmune therapies

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and SK Biopharmaceuticals, a Korean-based company leads the way in biotech innovation with groundbreaking drug research, development, and commercialization worldwide, announced a research and development collaboration at the BIO 2026 International Convention to discover AI-enabled innovative drug candidates in the neuroimmune area of the central nervous system.

22 Jun 2026

Statins may trigger muscle side effects by activating inflammatory danger signals

An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote low-level muscle myopathy by reducing isoprenoid-dependent protein prenylation rather than by cholesterol lowering. In primed muscle cells and mouse models, impaired YAP signaling, reduced glycolysis, NLRP3/caspase-1 activation, and nuclear FOXO accumulation increased atrogin-1, reduced protein synthesis, and weakened muscle function.

22 Jun 2026

Study links neuroimmune dysregulation to complex fibromyalgia symptoms

Fibromyalgia is a complex disorder characterized primarily by chronic widespread pain, fatigue and other physical and cognitive symptoms.

22 Jun 2026

How clinicians can identify and manage Ebola, hantavirus

Two deadly infectious diseases, Ebola https://www.cmaj.ca/lookup/doi/10.1503/cmaj.260834 and hantavirus https://www.cmaj.ca/lookup/doi/10.1503/cmaj.260789, have made headlines in recent weeks as they pose serious threats to public health.

22 Jun 2026

Estradiol changes may shape how much women move during the menstrual cycle

A 28-day wearable-sensor study of 26 healthy naturally menstruating women found that active energy expenditure varied across the menstrual cycle and was higher in the early follicular phase than the late follicular phase.

21 Jun 2026

Milken Institute and Ann Theodore Foundation fund early-career sarcoidosis research grants

The Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), in partnership with the Ann Theodore Foundation (ATF), today announced that the Ann Theodore Foundation Learning Opportunities in Medicine and Sarcoidosis (ATF-LOMAS) grant program has committed its first cycle of funding, totaling US$600,000 to early-career faculty conducting biomedical research in sarcoidosis.

19 Jun 2026

Massage gun use around eyes may cause serious retinal injuries

Using a massage gun on or around the eyes risks major tearing and bruising to the retina-the light sensitive tissue at the back of the eye-doctors warn in the online journal BMJ Case Reports after treating a young man who had used one of these devices.

18 Jun 2026

Parents' phone distraction linked to insecure attachment in teenagers

We worry about the time kids spend using screens - but what if the time their caregivers spend on phones is also harmful? Scientists working on digital mental health noticed increasing reports of teenagers struggling with their parents' phone use and decided to investigate.

18 Jun 2026

AI-designed drug for Parkinson's begins first human trial

Insilico Medicine ("Insilico", HKEX: 3696), a clinical-stage biotechnology company powered by generative artificial intelligence (AI), today announced it has achieved the first clinical milestone in its co-development collaboration with Hygtia Therapeutics with the completion of first-in-human dosing in the Phase I study of ISM8969.

17 Jun 2026

Novel embolization technique reduces pain from knee osteoarthritis

Embolization of abnormal blood vessels using rapidly resorbable gelatin-based microspheres is safe and provides significant, lasting pain relief and functional improvement for patients with osteoarthritis-related knee pain, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

16 Jun 2026

Naloxone provides life-saving tool to reverse opioid overdoses

Anyone can save a life during an opioid overdose with naloxone, a front-line defense in the nation's overdose crisis.

16 Jun 2026

Individual traits and cultural factors reshape how brains process musical emotion

A new study from the University of Jyväskylä shows who is more likely to experience mixed emotions while listening to music – and that our relationship with music is more complex and nuanced than we might assume.

16 Jun 2026

Bionic cooling skin accelerates healing and combats wound infections

As the global burden of infected wounds continues to rise-with over 300 million surgeries performed annually and postoperative infections affecting 5–20% of patients-conventional wound dressings face a critical limitation: no single product has successfully integrated protective function, wearing comfort, and efficient antibacterial activity.

15 Jun 2026

Short-chain oat fiber helps steady glucose and ease gut symptoms in pilot trial

A 14-day open-label pilot study in 63 healthy adults found that short-chain oat fiber was well tolerated at doses up to 20 g/day and was associated with improved gastrointestinal symptom scores.

14 Jun 2026

Genetic data may predict steroid side effect risk

Oral corticosteroids (OCSs) are widely used and effective in the treatment of chronic inflammatory conditions such as arthritis, asthma, and autoimmune diseases. They work by reducing inflammation, relieving pain, and calming the immune system.

14 Jun 2026

Physical activity declines after starting GLP-1 obesity treatments

Adults with obesity losing weight with glucagon-like peptide-1 (GLP-1) receptor agonist medications significantly decreased their physical activity, which is essential to protect muscle, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Phase 3 study of in vivo CRISPR therapy for hereditary angioedema successfully completed

Researchers from Amsterdam UMC, in collaboration with other hospitals, have successfully completed the first-ever Phase 3 study of an in vivo CRISPR therapy.

13 Jun 2026

Injectable wireless device offers new approach to control nerve activity

Researchers from NYU Abu Dhabi, in collaboration with Cleveland Clinic Abu Dhabi, have developed a tiny, injectable medical device that introduces a new approach to treating chronic pain and movement disorders by controlling nerve activity without the need for surgery, batteries, or wires, offering a simpler and less invasive way to treat neurological conditions.

12 Jun 2026

Experimental vaccine protects against fentanyl and related opioids

Fentanyl and related variants of the synthetic opioid kill more Americans each year than car accidents and gun violence combined. In too-high doses, the drugs hijack brain chemistry and shut down the signals that control breathing.

11 Jun 2026

Trial finds prunes do not outperform calcium and vitamin D for male bone density

A one-year randomized trial found that daily prune supplementation did not improve total or lumbar spine bone mineral density in older men susceptible to, or with, osteopenia. Although some bone turnover biomarkers differed between prune and control groups, these changes did not translate into measurable bone density benefits beyond calcium and vitamin D3 supplementation.

11 Jun 2026