Pain

Using a Pain Diary

A pain diary to record chronic pain patterns and triggers can be useful to improve control of pain management.

Chronic Pain: The 20 Most Painful Conditions

Antidepressants in Pain Management

See more featured articles »

Comparing Nociceptive and Neuropathic Pain

Pain in the Lower Right Abdomen: When to be Concerned

Latest Pain News and Research

For many patients leaving the ICU, the struggle has only just begun

The accident happened in Pittsburgh on Nov. 16. Joseph Masterson, a lawyer who was just days from retiring at age 63, suffered cardiac arrest while driving, plowed into a guardrail, and lost consciousness.

10 Apr 2026

IBS diagnosis gaps persist across racial and gender groups in the U.S.

A national survey study led by UCLA Health and Cedars-Sinai Medical Center found significant disparities in how irritable bowel syndrome, or IBS, is diagnosed across sex and racial groups in the U.S., with men and Black patients considerably less likely than women and white patients to receive a formal diagnosis.

9 Apr 2026

Study measures global burden of facial pain condition

Facial pain is one of the most common forms of chronic pain. Despite this, there has previously been no standardized burden measurements, such as impact on the individual and healthcare costs across countries and in relation to other diseases.

9 Apr 2026

Study finds gap in school-based dental care participation

Children who don't go to the dentist are less likely to participate in school-based cavity prevention programs, according to research published in JAMA Network Open.

9 Apr 2026

AI-powered chemistry accelerates discovery of selective cancer inhibitors

Recently, the Insilico team's research entitled "An Internal Sulfur-Lone Pair Interaction Enabled the Discovery of Potential and Sub-Family Selective PKMYT1 Inhibitors" was invited for publication as a cover Feature in ChemMedChem.

9 Apr 2026

Microplastics found in human bile may be associated with gallstones

Findings show microplastics in bile may trigger cellular senescence, suggesting a link to gallstone disease and highlighting the need for further research.

9 Apr 2026

Social support, physical health and spiritual engagement help older adults truly flourish

Older Canadians who are socially connected, physically healthy, and spiritually engaged are significantly more likely to experience complete mental health, according to a new nationally representative study examining adults aged 65 and older.

8 Apr 2026

Insilico Medicine nominates AI-driven drug candidate for cancer, Cushing's syndrome and obesity

The NR3C1 (nuclear receptor subfamily 3 group C member 1) gene encodes the glucocorticoid receptor (GR), a nuclear receptor vital for maintaining physiological homeostasis, and inhibition of NR3C1 could increase the sensitivity of cancer cells to standard chemotherapy, particularly in ovarian cancer.

8 Apr 2026

Duloxetine fails to prevent nerve damage caused by chemotherapy

A randomized trial conducted by the Alliance for Clinical Trials in Oncology with support from the National Cancer Institute has found that duloxetine, a medication commonly used to treat chronic pain and psychiatric conditions, does not prevent nerve damage caused by chemotherapy in patients with colorectal cancer.

8 Apr 2026

Long-term study links common IBS medications to mortality risk

A large, long-term study led by Cedars-Sinai Health Sciences University investigators suggests that some medications commonly prescribed to treat irritable bowel syndrome (IBS)-including antidepressants-may be associated with a small but measurable increase in the risk of death.

8 Apr 2026

Urgent care clinics move to fill abortion care gaps in rural areas

Providing abortions was the last thing Shawn Brown thought she'd be doing when she opened an urgent care clinic in this remote town in Michigan's Upper Peninsula.

8 Apr 2026

World Health Day 2026: WHO urges global collaboration and science for better health

The World Health Organization (WHO) today calls on people everywhere to renew their commitment to working together and supporting science as the twin engines driving better health, under the World Health Day 2026 theme: "Together for health. Stand with science."

6 Apr 2026

Metformin mimics exercise-related metabolic effects in prostate cancer patients

A new study has found that metformin, a widely prescribed diabetes drug, may mimic one of exercise's core biological effects in men with prostate cancer, raising levels of a molecule tied to energy balance and weight control even when patients are inactive.

6 Apr 2026

State-run insurance plans for foster kids leave some of them without doctors

Ollie Super has moved in and out of cancer treatment since she was diagnosed with neuroblastoma as a toddler in foster care. Now 8, the second grader is dealing with it again. Her cancer came back late last year.

2 Apr 2026

Celiac disease weakens gut microbes that digest fiber

Findings suggest that impaired fiber metabolism in celiac disease is due to microbial deficits, not just diet, emphasizing the need for targeted interventions.

2 Apr 2026

New brain circuit discovery offers hope for chronic pain treatment

A new map of a brain circuit specific to chronic pain suggests a promising route to treatment for the roughly 60 million Americans living with persistent pain, according to a study published in Nature.

1 Apr 2026

Gene-edited treatment shows promising outcomes for severe sickle cell disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

1 Apr 2026

Highly potent opioid shows potential as therapy for pain and opioid use disorder

Researchers at the National Institutes of Health (NIH) have identified a novel, highly potent opioid that shows potential as a therapy for both pain and opioid use disorder.

1 Apr 2026

Kinesio taping offers limited benefits for treating musculoskeletal pain and mobility

Kinesio taping, or 'KT tape' as it's usually known-widely used to ease joint/muscle pain and boost range of movement-may not be all that effective, suggests a pooled data analysis of the existing evidence, published in the online journal BMJ Evidence Based Medicine.

1 Apr 2026

Fiber supplement stabilizes blood sugar in gestational diabetes

Dietary fiber supplementation shows potential in managing blood sugar levels and preventing preterm births in pregnancies at risk for gestational diabetes.

1 Apr 2026