Pain

Using a Pain Diary

A pain diary to record chronic pain patterns and triggers can be useful to improve control of pain management.

Comparing Nociceptive and Neuropathic Pain

Pain in the Lower Right Abdomen: When to be Concerned

Antidepressants in Pain Management

Chronic Pain: The 20 Most Painful Conditions

Latest Pain News and Research

Novel peptide approach reduces chronic neuropathic pain in mice

Understanding and treating chronic neuropathic pain has remained challenging due to its complex nature. New research from the lab of Clifford Woolf, MB, BCh, PhD, at Boston Children's Hospital's FM Kirby Neurobiology Center describes a novel approach for reducing pain by disrupting interactions within pain-sensing nerve cells called nociceptors

6 Oct 2026

Targeting the brain's Default Mode Network may help better manage chronic low back pain

Low back pain is the single leading cause of disability worldwide, according to the World Health Organization.

6 Oct 2026

Cannabis products associated with sustained improvements in patients with inflammatory arthritis

The sustained use of medical cannabis preparations provides safe and effective relief for patients with inflammatory arthritis, according to observational data published in the journal Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders.

6 Oct 2026

One Health approach could improve India’s response to mycetoma

A 60-year-old Indian farmer developed two infections—one in his foot following an injury from a cow's hoof, the other in his buttock after a thorn prick in the fields three years later.

5 Oct 2026

Online approach helped patients manage anxiety after chest pain

The PACER study reveals that peer-supported CBT significantly lowers anxiety in low-risk chest pain patients, enhancing mental health in emergency settings.

2 Oct 2026

NCCN introduces first-ever evidence-based guidelines for pediatric bone sarcoma

Today, the National Comprehensive Cancer Network (NCCN) published the first-ever edition of NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Bone Sarcoma.

1 Oct 2026

CBL-514 injection reduces visceral and subcutaneous fat in trials

Details of a new injection that targets fat cells will be released at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

1 Oct 2026

New framework maps depression symptoms to unique brain circuits

A research team from the Sant Pau Research Institute (IR Sant Pau) has published a scientific review proposing a paradigm shift in the way depression is understood and studied.

1 Oct 2026

Bioinspired sensor mimics haptic and pain perception for prosthetics

Lower-limb amputation not only impairs mobility but is also frequently accompanied by phantom limb pain and disrupted haptic and nociceptive perception in the residual limb, which can compromise prosthetic use and rehabilitation.

1 Oct 2026

Esophageal cancer leaves a distinct metabolic signature in the gut

The study uncovers gut microbial and metabolic signatures in esophageal cancer, emphasizing lipid dysregulation and its potential role in disease progression.

1 Oct 2026

Wearable AI forecasts prolonged sitting in women with chronic pelvic pain disorders

Researchers at the Icahn School of Medicine at Mount Sinai have developed an artificial intelligence (AI) approach using data from wearable devices that can forecast upcoming periods of prolonged sitting in women with chronic pelvic pain disorders.

30 Sep 2026

Exercise therapy reduces knee osteoarthritis risk after ACL surgery

Exercise-based rehabilitation and education can reduce the chance of knee osteoarthritis following ACL reconstruction in people aged under 40, as well as improve pain and quality of life, a study by La Trobe University researchers has found.

29 Sep 2026

Experimental mRNA therapy protects the liver after acetaminophen overdose

When a patient arrives at the hospital with an acetaminophen overdose, it's often a race against the clock. The only FDA-approved antidote for overdose-related liver injury, N‑acetylcysteine, must be administered within hours to be effective.

28 Sep 2026

Childhood cancer survivors face severe mental health challenges as adults

Consultant and researcher Magnus Aasved Hjort believes that people who survive childhood cancer should receive far better support as adults.

28 Sep 2026

Low-dose radiation shows lasting benefits in patients with knee osteoarthritis

Low-dose radiation therapy may do more than relieve pain from early knee osteoarthritis, with a long-term analysis suggesting it could also influence how the disease progresses.

27 Sep 2026

Long-term endocrine therapy adherence remains low after breast cancer surgery

Many patients with early-stage breast cancer do not consistently maintain the long-term hormone therapy prescribed after lumpectomy, a large U.S. insurance claims analysis indicates.

27 Sep 2026

Ultra-low-dose radiation therapy eases painful bone lesions in multiple myeloma

A short course of ultra-low-dose radiation therapy relieved painful bone lesions from multiple myeloma for most patients in a multi-institutional phase 2 clinical trial.

27 Sep 2026

Nasal spray offers needle-free pain relief for children with injuries

A treatment for pain, that is delivered via a nasal spray, offers an effective, needle-free option for children being seen in the emergency department for a range of injuries, according to research presented at the European Emergency Medicine Congress today (Sunday).

27 Sep 2026

Virtual reality and music may help lower blood pressure during emergencies

A virtual reality landscape of a flowing river and trees, accompanied by classical music, can help to reduce patients' blood pressure significantly within 15 minutes of their being seen in an emergency department.

25 Sep 2026

UC researcher receives funding to study bone complications in people with sickle cell disease

September is National Sickle Cell Awareness Month, and a University of Cincinnati College of Medicine hematology researcher has received new grant funding to study one of the disease's painful, under-recognized complications: bone damage.

25 Sep 2026