Pain

Using a Pain Diary

A pain diary to record chronic pain patterns and triggers can be useful to improve control of pain management.

Chronic Pain: The 20 Most Painful Conditions

Antidepressants in Pain Management

Pain in the Lower Right Abdomen: When to be Concerned

Comparing Nociceptive and Neuropathic Pain

Latest Pain News and Research

Maternal opioid use in pregnancy linked to childhood hospitalizations

Children whose mothers received opioid prescriptions during pregnancy have a higher rate of hospital admission in childhood than unexposed children, including unexposed siblings, according to a new study published October 13th in the open access journal PLOS Medicine by Dong Keon Yon of Kyung Hee University College of Medicine, South Korea, and colleagues.

13 Oct 2026

Women with autoimmune diseases more likely to receive psychiatric misdiagnoses

Females with autoimmune diseases are significantly more likely than males to have their autoimmune disease misdiagnosed as a psychiatric or psychosomatic condition, according to a study of more than 6,600 patients.

12 Oct 2026

Your favorite song might make a needle prick hurt less

A study of 204 patients undergoing intravenous cannulation before MRI found that those listening to their favorite music reported significantly lower pain scores than patients hearing no music at 30 seconds and two minutes after puncture. Mozart was also associated with lower pain scores among patients with pre-existing pain, while relaxation music showed no significant benefit, although the non-randomized findings require confirmation.

12 Oct 2026

Study identifies Piezo channels as targets for orthodontic care

A new review in Genes & Diseases highlights Piezo channels as important biological links between mechanical forces and the cellular processes that shape the face, move teeth and influence oral health.

12 Oct 2026

Review highlights EP4 receptor as target for inflammatory diseases

A review published in Genes & Diseases highlights the prostaglandin E2 receptor subtype 4 (EP4) as an important regulator of inflammation and a promising therapeutic target for a wide range of inflammatory and inflammation-related diseases.

12 Oct 2026

Severe long Covid associated with distinct oral and lung microbiomes

A study of more than 700 people has shown that those with long Covid have distinct differences in the mix of bacteria that live in their mouths and lungs, according to a study published today (Monday) in the European Respiratory Journal.

11 Oct 2026

Gut bacteria may help explain why endometriosis pain varies

A study of 50 women with surgically confirmed endometriosis found that differences in gut bacterial composition were associated with menstrual pain, urinary symptoms, and infertility.

9 Oct 2026

Expert consensus statement outlines shared medical appointments to improve chronic disease care

The American College of Lifestyle Medicine (ACLM) has published an expert consensus statement identifying best practices for delivering lifestyle interventions through shared medical appointments (SMAs), a care model that combines individualized medical care with group support.

8 Oct 2026

A study spanning 118 countries reveals a divide in pain and aging

Global pain trajectories indicate that while some pain types peak early, musculoskeletal pain increases with age, challenging aging assumptions.

8 Oct 2026

Hydroxyurea does not increase infection risk in children with sickle cell anemia

Children living with sickle cell anemia have no higher incidence of clinically diagnosed infections when treated with hydroxyurea.

8 Oct 2026

Warning signs for chronic pelvic pain emerge during adolescence

A new McMaster University study of nearly half a million people has found that many people who go on to develop chronic pelvic pain (CPP) may have been showing warning signs years before diagnosis, offering a potential opportunity to identify people at increased risk earlier in life.

7 Oct 2026

Long-term opioid use does not improve chronic back pain outcomes

Taking opioids for years does not seem to improve pain and functioning in people with chronic back pain, according to a new Northwestern University study that compared 70 long-term opioid users to 70 similar patients not taking opioids.

6 Oct 2026

Blood protein patterns may help explain pain levels in sickle cell disease

A small pilot study led by a Rutgers researcher has found differences in blood proteins between people experiencing high and low levels of pain from sickle cell disease, findings that may inform research on new treatments and better pain management.

6 Oct 2026

Study identifies RGS4 protein as potential target for chronic pain

Chronic pain can continue long after an initial injury. When a nerve outside the brain and spinal cord (a peripheral nerve) is damaged and does not heal properly, it keeps sending constant pain signals.

6 Oct 2026

Genetic and tissue analysis reveals new targets for lymphatic malformations

Lymphatic malformations are rare disorders in which lymph vessels develop abnormally, often beginning in childhood and sometimes causing swelling, infection, bleeding, pain, or airway obstruction.

6 Oct 2026

Novel peptide approach reduces chronic neuropathic pain in mice

Understanding and treating chronic neuropathic pain has remained challenging due to its complex nature. New research from the lab of Clifford Woolf, MB, BCh, PhD, at Boston Children's Hospital's FM Kirby Neurobiology Center describes a novel approach for reducing pain by disrupting interactions within pain-sensing nerve cells called nociceptors

6 Oct 2026

Targeting the brain's Default Mode Network may help better manage chronic low back pain

Low back pain is the single leading cause of disability worldwide, according to the World Health Organization.

6 Oct 2026

Cannabis products associated with sustained improvements in patients with inflammatory arthritis

The sustained use of medical cannabis preparations provides safe and effective relief for patients with inflammatory arthritis, according to observational data published in the journal Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders.

6 Oct 2026

One Health approach could improve India’s response to mycetoma

A 60-year-old Indian farmer developed two infections—one in his foot following an injury from a cow's hoof, the other in his buttock after a thorn prick in the fields three years later.

5 Oct 2026

Online approach helped patients manage anxiety after chest pain

The PACER study reveals that peer-supported CBT significantly lowers anxiety in low-risk chest pain patients, enhancing mental health in emergency settings.

2 Oct 2026