Pain

Using a Pain Diary

A pain diary to record chronic pain patterns and triggers can be useful to improve control of pain management.

Pain in the Lower Right Abdomen: When to be Concerned

Antidepressants in Pain Management

Chronic Pain: The 20 Most Painful Conditions

Comparing Nociceptive and Neuropathic Pain

Latest Pain News and Research

Artery scans detect “silent atherosclerosis” in 1 in 13 adults under 30

Researchers studying 16,808 adults aged 18 to 70 found that silent atherosclerosis was detectable in early adulthood, with plaque present in 57.1% of those who completed imaging across three arterial territories. Plaque prevalence and burden were higher in older age groups, with men showing earlier evidence of disease than women, while conventional cardiovascular risk scores identified relatively few people with existing plaque.

10 Nov 2026

Tobacco use independently linked to anorectal sensorimotor dysfunction and fecal incontinence

Tobacco use is independently associated with anorectal sensorimotor dysfunction and fecal incontinence, according to a recent study published ahead of print in The American Journal of Gastroenterology.

10 Nov 2026

A weight-loss drug eased knee arthritis pain in two major trials

Retatrutide effectively alleviates knee pain and enhances mobility in obese osteoarthritis patients, but long-term safety and joint health remain uncertain.

10 Nov 2026

Why are some patients lying to their doctors to get antibiotics?

A study finds 28% of adults misrepresent symptoms to secure antibiotics, highlighting risks for antimicrobial resistance and the need for better communication.

10 Nov 2026

Complex procedure offers relief for children with chronic pancreatitis

Acute recurrent pancreatitis or chronic pancreatitis can take an enormous toll on children, causing severe pain and repeated hospitalizations.

9 Nov 2026

ASA urges CMS to protect Medicare's physician supervision standard for anesthesia care

The American Society of Anesthesiologists (ASA) today urged the Centers for Medicare & Medicaid Services (CMS) to preserve Medicare's longstanding physician supervision standard for anesthesia care, warning that weakening or eliminating the standard would remove an important Medicare patient-safety safeguard.

9 Nov 2026

Blood biomarker tracks nerve damage from oxaliplatin-containing adjuvant chemotherapy

Oxaliplatin can cause numbness, tingling, and pain in the hands and feet, with consequences for mobility, work, and quality of life.

9 Nov 2026

Early heart procedures do not improve long-term survival in stable heart disease

Patients with stable heart disease and abnormal stress tests who have invasive procedures early in their care do not live longer than those initially treated with drugs and lifestyle changes alone, an international study shows.

8 Nov 2026

Retatrutide reduces knee pain and body weight in osteoarthritis patients

For people with painful knee osteoarthritis (OA) who are overweight or have obesity, everyday activities such as walking, climbing stairs and standing up from a chair can be difficult.

8 Nov 2026

Seasonal allergies may be driving recurrent sinus infections

"Every spring, I get sick. Then it happens again in the fall." If you have frequent sinus symptoms that follow a seasonal pattern, allergies may be the root cause. Seasonal allergies can cause congestion, drainage, facial pressure, and fatigue.

6 Nov 2026

Biodegradable microneedle particles improve drug delivery through the skin

Your skin is remarkably good at keeping things out of your body. Typically, that's a positive. It becomes an issue when medicine needs to get in.

6 Nov 2026

Virtual reality reduces anxiety among children awaiting surgery

Children who used a virtual reality (VR) headset before surgery showed reduced self-reported distress and fear, along with lower heart rate and blood pressure, according to a new study published November 5th in the open access journal PLOS Digital Health by Dayanjan Wijesinghe of Virginia Commonwealth University, US, and colleagues.

5 Nov 2026

Struggling with constipation? Two green kiwifruits a day may help

A narrative review of 33 publications found that consuming two fresh green kiwifruits daily for approximately four weeks can improve bowel movement frequency and gastrointestinal comfort in adults with functional constipation or constipation-predominant irritable bowel syndrome (IBS-C). Clinical studies reported broadly similar improvements with kiwifruit, psyllium, and prunes, although more research is needed to establish long-term benefits and differences between kiwifruit varieties.

5 Nov 2026

Review examines translational bottlenecks for plant-derived anti-inflammatory compounds

A review led by Professor Weidong Zhang at the School of Pharmacy, Naval Medical University, was published in Volume 2 of the journal Immunity & Inflammation on October 27, 2026. The article systematically examines the translational bottlenecks and potential solutions for plant-derived anti-inflammatory compounds.

5 Nov 2026

Topadur’s Phase 2a trial of TOP-N53 for systemic sclerosis-associated digital ulcers advances to next dose levels

Topadur Pharma AG, a Swiss clinical-stage biopharmaceutical company, today announced that the Safety Review Committee of its Phase 2a trial has recommended progression to the next planned dose levels.

5 Nov 2026

UCLA advances CRISPR gene-editing therapy for sickle cell disease

A UCLA-led team has described how they advanced an experimental CRISPR approach for sickle cell disease into a blood stem cell therapy that can be manufactured at the scale and quality required for a clinical trial.

4 Nov 2026

Women with DCIS may not need routine imaging after double mastectomy

Women who have undergone a double mastectomy to treat ductal carcinoma in situ (DCIS), a noninvasive form of breast cancer also known as stage 0 breast cancer, may not benefit from routine mammograms or other breast imaging after surgery, according to a new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center.

4 Nov 2026

Rutgers specialist launches awareness initiative for often-misdiagnosed tailbone pain

Thousands of people suffer with tailbone pain, often struggling to find an accurate diagnosis and effective treatment.

4 Nov 2026

Exercise may improve mood and memory, and researchers say doctors should prescribe it

In a Viewpoint, researchers examined evidence that exercise can reduce symptoms of depression and anxiety, support cognition, and may help lower the risk of cognitive decline, although evidence for dementia prevention remains largely observational. The authors argue that exercise should be prescribed as a structured component of brain-health care, with individualized recommendations that account for medical conditions, safety, and barriers to participation.

4 Nov 2026

A low-calorie diet and exercise helped 54% of younger adults achieve diabetes remission

In a randomized clinical trial involving 96 adults with early-onset type 2 diabetes and obesity, a 24-week program combining a low-energy diet with supervised exercise achieved diabetes remission in 54% of participants, compared with 4% receiving usual care. The intervention also reduced body fat, largely preserved muscle mass, and improved strength and body-mass-adjusted fitness, although the additional benefits attributable specifically to exercise remain uncertain.

3 Nov 2026