Pain

Using a Pain Diary

A pain diary to record chronic pain patterns and triggers can be useful to improve control of pain management.

Pain in the Lower Right Abdomen: When to be Concerned

Antidepressants in Pain Management

Chronic Pain: The 20 Most Painful Conditions

Comparing Nociceptive and Neuropathic Pain

Latest Pain News and Research

Researchers identify molecular targets to treat painful nerve neuromas

Human peripheral nerves have a remarkable ability to regenerate after damage. However, when re-growing axons fail to meet their target organ, they can transform into painful neuromas.

11 Aug 2026

Medical reassurance often stops patients from seeking treatment

Doctors may think they're saying "Don't panic." But many patients hear "Don't bother" instead.

10 Aug 2026

New drug delivers promising survival gains in pancreatic cancer

About 90% of people with pancreatic cancer have pancreatic ductal adenocarcinoma (PDAC), which is driven by an activating mutation in the KRAS gene.

9 Aug 2026

Targeting small group of brain cells may reduce opioid addiction risk

Researchers at Duke University School of Medicine are investigating how to keep opioids' pain-relieving benefits while reducing their addictive potential. In a study published in Nature, they report a step toward that goal.

7 Aug 2026

Piezo ion channels: Key regulators of digestive health and disease

Mechanosensitive Piezo ion channels, particularly Piezo1 and Piezo2, are gaining recognition as central regulators of digestive system physiology and disease.

7 Aug 2026

New review explores purinergic signaling pathways in osteoarthritis progression

A growing understanding of purinergic signaling is reshaping how scientists view osteoarthritis (OA), revealing an intricate communication network that influences joint inflammation, cartilage degeneration, bone remodeling, and chronic pain.

7 Aug 2026

New research aims to switch off chronic pain at its source

A major new Adelaide University research program will strive to improve the lives of millions by developing targeted therapies for chronic visceral pain, a debilitating primary symptom associated with irritable bowel syndrome (IBS), inflammatory bowel disease (IBD) and endometriosis.

7 Aug 2026

Scientists map key differences in stem cell potency for treating knee osteoarthritis

Knee osteoarthritis (KOA) affects more than 1 in 10 people over 40 years of age, impairing patients' mobility and quality of life.

7 Aug 2026

Firearm injury patients face measurable risk of bacterial infections

A new study from researchers at the University of Maryland School of Medicine (UMSOM) found that bacterial infections develop in approximately 5 percent of adults hospitalized with firearm injuries, with most infections occurring during the initial hospitalization rather than after patients return home.

6 Aug 2026

Multi-omics research uncovers new therapeutic targets for Fabry disease

A comprehensive review is shedding new light on Fabry disease, a rare inherited disorder that can progressively damage multiple organs and significantly affect quality of life.

6 Aug 2026

Combining genetics and AI to discover new osteoarthritis drugs

Osteoarthritis (OA) is a chronic, painful joint disease and a leading cause of disability. Despite its prevalence, therapies for osteoarthritis are limited and focus on symptom management.

6 Aug 2026

Digital care app improves quality of life for breast cancer patients

Regularly checking in with patients with metastatic breast cancer by way of an app to enquire about their well-being – and responding promptly – can alleviate their debilitating fatigue and make their daily lives easier.

6 Aug 2026

Live tracking reveals how robotic surgery impacts surgeon stress

Robot-assisted surgery (RAS) is one of the most advanced tools in modern medicine. These systems give surgeons extreme precision, allowing procedures to be performed through small incisions that minimize both pain and recovery time.

6 Aug 2026

Genetic changes in zebrafish reveal new pathways for back pain

Neck and back pain could be caused by changes in gene activity that trigger the breakdown of the spine's natural shock absorbers, new research suggests.

6 Aug 2026

Nerve-tumor interactions emerge as a transformative frontier in oncology

A new review article highlights a rapidly emerging frontier in oncology: the dynamic and influential relationship between nerves and tumors.

6 Aug 2026

Nerve-blocking therapy improves growth plate repair in injured bones

With the support of National Institutes of Health funding, Johns Hopkins Medicine investigators, led by pathologist Aaron W. James, M.D., Ph.D., previously discovered that sensory neurons in skeletal tissue are constantly sensing their environment and are quick to respond to injuries.

5 Aug 2026

Neuroscience-informed therapy provides massive cost-savings for opioid addiction treatment

A new economic evaluation from the University of California San Diego School of Medicine has revealed that Mindfulness-Oriented Recovery Enhancement (MORE) - an innovative, evidence-based, neuroscience-informed therapy for opioid misuse and chronic pain - provides $12 in cost savings for every dollar spent, between two and six times more cost effective than other addiction treatments such as residential or intensive outpatient treatment.

5 Aug 2026

Cellular senescence drives progression of spinal disc degeneration and pain

A growing body of scientific insight is drawing attention to cellular senescence as a central force in the progression of intervertebral disc degeneration (IDD), a leading contributor to chronic low back pain worldwide.

5 Aug 2026

Medical cannabis compound alleviates nightmares associated with PTSD

Nightmares are among the most agonizing symptoms of post-traumatic stress disorder (PTSD) – a condition that can develop after exposure to severe traumatic experiences, such as disasters, serious accidents, acts of violence, or wartime experiences. Individuals affected relive the events intensely at night, as if they were real, time and time again.

5 Aug 2026

Air pollution may worsen rheumatoid arthritis symptoms and flare risk

A novel study shows that exposure to air pollution, especially fine particulate matter like dust, soot, and smoke (PM2.5), is associated with increased disease activity and flare risk in rheumatoid arthritis (RA).

5 Aug 2026