Pain News and Research

Latest Pain News and Research

Researchers explore brain activity linking nicotine withdrawal and pain sensitivity

Abstinent smokers experience increased pain sensitivity during withdrawal, to the point that they often require more pain relief after surgery.

8 Dec 2025

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Adults with chronic pain who participated in New York State's (NYS) Medical Cannabis Program were significantly less likely to require prescription opioids, according to a new study published today in JAMA Internal Medicine and led by researchers at Albert Einstein College of Medicine and Montefiore Health System.

8 Dec 2025

Novel wireless device uses light to send information directly to the brain

In a new leap for neurobiology and bioelectronics, Northwestern University scientists have developed a wireless device that uses light to send information directly to the brain - bypassing the body's natural sensory pathways.

8 Dec 2025

A slow-growing, bone-covered, noncancerous mass named as ossifying spindled and epithelioid tumor

It's not often that a pathologist gets to make a diagnosis that works for the patient by preventing treatment from occurring.

8 Dec 2025

A North Carolina hospital was slated to open in 2025. Mired in bureaucracy, it’s still a dirt field.

Madison County, tucked in the mountains of western North Carolina, has no hospital and just three ambulances serving its roughly 22,000 people.

8 Dec 2025

Virtual diet and exercise program shows promise in reducing lymphoma treatment side effects

Patients undergoing treatment for lymphoma often experience adverse side effects that can be so severe that they stop or slow treatment.

7 Dec 2025

Walking speed before surgery predicts who thrives after hip replacement

This study shows that preoperative gait speed is a strong predictor of patient-reported pain relief, function, and joint awareness after total hip arthroplasty for osteoarthritis. A walking speed of at least 1.0 m/s before surgery independently predicts excellent postoperative outcomes.

7 Dec 2025

Challenges and opportunities in delivering gene therapies for sickle cell disease and beta thalassemia

The first study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing demand for gene therapies in the coming years.

7 Dec 2025

Most sickle cell patients face long delays for recommended pain relief, study shows

A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by the American Society of Hematology (ASH) and National Heart, Lung, and Blood Institute (NHLBI).

6 Dec 2025

Exa-cel shows complete success in early pediatric trials for sickle cell disease and beta-thalassemia

Preliminary results from two trials of the gene therapy exagamglogene autotemcel (exa-cel) suggest the therapy offers an effective cure for beta-thalassemia and sickle cell disease in children younger than 12.

6 Dec 2025

New Lancet case study series highlights how social forces shape patient health

In November, The Lancet, one of the world's most esteemed medical journals, launched a new monthly series of case studies that goes beyond clinical diagnoses to illuminate the social and cultural forces that contribute to each patient's condition.

5 Dec 2025

Modern pollutants and ancient genetic variants could explain why some women develop endometriosis

A new study suggests that certain genetic differences, passed down from ancient human ancestors, and exposure to common present-day chemicals could explain why some women are more likely to develop endometriosis.

5 Dec 2025

Study shines light on how P2X4 receptor can be inhibited

A study carried out by the University of Bonn and the University Hospital Bonn throws light on how an important receptor can be inhibited.

5 Dec 2025

First new fibromyalgia drug in 15 years, Tonmya (cyclobenzaprine HCl) gains FDA approval and hits pharmacy shelves

In a milestone moment for chronic pain management, Tonix Pharmaceuticals announced on August 15, 2025, that its novel sublingual therapy Tonmya has received approval from the U.S. Food and Drug Administration (FDA) - marking the first new drug for Fibromyalgia in more than 15 years.

From Hanson Wade Group - Non-Opioid Pain Therapeutics Summit 5 Dec 2025

Concussion history accurately predicts long-term health in former NFL players

A UNC-Chapel Hill study conducted by the Matthew Gfellar Center studied more than 1,500 former NFL players found that two of the most commonly used ways to estimate head injury risk, years played and playing position, are not actually linked to poorer long-term physical or mental health.

4 Dec 2025

Dark web users show markedly higher mental health vulnerabilities

The dark web – a hidden corner of the internet accessed through privacy-preserving tools like the Tor browser – operates beyond the reach of traditional search engines and public platforms.

3 Dec 2025

Medical cannabis evidence falls short for most conditions

Medical cannabis lacks adequate scientific backing for most of the conditions it is commonly used to treat, including chronic pain, anxiety and insomnia, according to a comprehensive review led by UCLA Health.

3 Dec 2025

How anger and injustice shape the course of chronic pain

We all know stress can worsen pain, but new research shows that anger and a sense of injustice may be even more powerful triggers. In a study of more than 700 people living with chronic pain, researchers uncovered four distinct "anger profiles" that help explain why some patients hurt more, and longer, than others.

3 Dec 2025

A personalized approach to treating pancreatic cancer

It's not surprising that pancreatic cancer is often referred to as a silent killer. With few early symptoms and an aggressive nature, it has one of the lowest survival rates of all cancers.

3 Dec 2025

Mindfulness can help reduce problematic smartphone use

With more than four billion people around the globe owning a smartphone, researchers are now looking at ways to reduce a growing public health concern-problematic smartphone use.

3 Dec 2025

Pain News and Research

Latest Pain News and Research

Researchers explore brain activity linking nicotine withdrawal and pain sensitivity

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Novel wireless device uses light to send information directly to the brain

A slow-growing, bone-covered, noncancerous mass named as ossifying spindled and epithelioid tumor

A North Carolina hospital was slated to open in 2025. Mired in bureaucracy, it’s still a dirt field.

Virtual diet and exercise program shows promise in reducing lymphoma treatment side effects

Walking speed before surgery predicts who thrives after hip replacement

Challenges and opportunities in delivering gene therapies for sickle cell disease and beta thalassemia

Most sickle cell patients face long delays for recommended pain relief, study shows

Exa-cel shows complete success in early pediatric trials for sickle cell disease and beta-thalassemia

New Lancet case study series highlights how social forces shape patient health

Modern pollutants and ancient genetic variants could explain why some women develop endometriosis

Study shines light on how P2X4 receptor can be inhibited

First new fibromyalgia drug in 15 years, Tonmya (cyclobenzaprine HCl) gains FDA approval and hits pharmacy shelves

Concussion history accurately predicts long-term health in former NFL players

Dark web users show markedly higher mental health vulnerabilities

Medical cannabis evidence falls short for most conditions

How anger and injustice shape the course of chronic pain

A personalized approach to treating pancreatic cancer

Mindfulness can help reduce problematic smartphone use

Innovation in neuroscience drug discovery - eBook eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Pain News and Research

Latest Pain News and Research

Innovation in neuroscience drug discovery - eBook eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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