Pain News and Research

Latest Pain News and Research

GLP-1 drugs calm inflammation beyond diabetes and weight loss

This Journal of Clinical Investigation review describes how glucagon-like peptide-1 (GLP-1)–based medicines reduce systemic and tissue inflammation through both weight-dependent and weight-independent mechanisms. It details preclinical and clinical evidence linking GLP-1 receptor activation to cardiovascular, renal, hepatic, neural, and joint anti-inflammatory effects while outlining uncertainties and future research needs.

4 Nov 2025

Over one-third of men would rather endure stressful situations than discuss prostate health

A new survey from Orlando Health reveals that over one-third of men (38%) would rather endure stressful situations, such as watching their team lose a big game or being stuck in traffic, than discuss their prostate health.

4 Nov 2025

Indoor hydroponic gardening boosts wellbeing for cancer patients

Indoor hydroponic gardening - a method of growing plants using nutrient-rich water instead of soil - could help cancer patients develop better mental health, eat a healthier diet and enjoy a better overall quality of life.

4 Nov 2025

Personalized pain care could greatly improve life for Australians with Parkinson’s

Every 27 minutes, someone in Australia is diagnosed with Parkinson's disease. Best known for its tremors, movement and balance issues, it also brings another, often overlooked burden – persistent pain.

3 Nov 2025

AI in Healthcare: How generative tools are transforming clinical practice

Discover how generative AI is reshaping clinical care with real-world examples, challenges, and expert advice for AI adoption in healthcare

3 Nov 2025

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest receptors into precision tools - opening the door to a new generation of safer, smarter medicines.

31 Oct 2025

Novel approaches to understanding EETs and cardiovascular disease

Some products of arachidonic acid have already been well studied: the prostanoids formed by cyclooxygenases are central mediators of inflammation, fever, and pain.

31 Oct 2025

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms — pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination.

31 Oct 2025

Unusual presentation of vulvar mucinous cyst with multiple bartholin cysts in a reproductive-age woman

A new case report was published in Volume 12 of Oncoscience on October 9, 2025, titled "Vulvar mucinous cyst mimicking common lesions with concurrent multiple bartholin cysts in a reproductive-age woman: A rare case report and review of literature."

30 Oct 2025

Some hormonal contraceptives linked to higher risk of breast cancer

Some common hormonal contraceptives are linked to a slightly higher risk of breast cancer than others.

30 Oct 2025

Scientists uncover why many cancer patients develop chemotherapy-induced neuropathy

Scientists at Wake Forest University School of Medicine, in collaboration with researchers at Weill Cornell Medicine, have made a breakthrough in understanding why many cancer patients develop nerve damage after chemotherapy.

30 Oct 2025

Home exercise alone highly effective for meniscal tear and osteoarthritis pain, says study

People with a meniscal tear and osteoarthritis prescribed home exercises with or without physical therapy reported substantial improvements in knee pain, according to a new study led by Mass General Brigham researchers.

30 Oct 2025

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Peripheral afferent neurons - nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord) - are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often accompanied by severe pain.

29 Oct 2025

Study highlights high prevalence of non-coeliac gluten sensitivity lacking clear markers

Around one in ten people worldwide report gastrointestinal and other symptoms such as fatigue and headache after eating foods containing gluten or wheat despite not having a diagnosis of either coeliac disease or wheat allergy, finds a large systematic review and meta-analysis published online in Gut.

29 Oct 2025

$Reducing femoral fractures in total hip replacement with safer implant designs$

Reducing femoral fractures in total hip replacement with safer implant designs

As populations continue to age, total hip replacement (THR) is becoming an increasingly common surgical procedure.

28 Oct 2025

Study links poor sleep to adverse health outcomes in seniors

Sleep problems affect more than one in five residents in long-term care facilities, with pain, daytime napping and certain medications emerging as key contributors.

28 Oct 2025

Study highlights need to establish clinical practice guidelines for surgical patients receiving MOUDs

In an effort to stem the death toll from opioid overdose, United States public health officials have promoted the prescription and use of medications like buprenorphine that blunt the effects of illicit opioids such as fentanyl.

27 Oct 2025

Adequate support needed to address Canada's rising youth opioid use

Youth opioid use is increasing in Canada, as are related emergency department visits and deaths, yet governments are not providing adequate support to address this public health crisis, argue the authors of a CMAJ.

27 Oct 2025

Research shows a decline in opioid dispensing across Canadian provinces

Efforts to promote safer opioid prescribing in Canada appear to be having an effect, as new research in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250670 shows a decrease in opioid dispensing between 2018 and 2022.

27 Oct 2025

Excess mortality associated with chronic pain can be avoided through spinal cord stimulation

Treating chronic neuropathic pain with spinal cord stimulation may help prevent excess mortality associated with chronic pain, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

27 Oct 2025

Pain News and Research

Latest Pain News and Research

GLP-1 drugs calm inflammation beyond diabetes and weight loss

Over one-third of men would rather endure stressful situations than discuss prostate health

Indoor hydroponic gardening boosts wellbeing for cancer patients

Personalized pain care could greatly improve life for Australians with Parkinson’s

AI in Healthcare: How generative tools are transforming clinical practice

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

Novel approaches to understanding EETs and cardiovascular disease

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

Unusual presentation of vulvar mucinous cyst with multiple bartholin cysts in a reproductive-age woman

Some hormonal contraceptives linked to higher risk of breast cancer

Scientists uncover why many cancer patients develop chemotherapy-induced neuropathy

Home exercise alone highly effective for meniscal tear and osteoarthritis pain, says study

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Study highlights high prevalence of non-coeliac gluten sensitivity lacking clear markers

Reducing femoral fractures in total hip replacement with safer implant designs

Study links poor sleep to adverse health outcomes in seniors

Study highlights need to establish clinical practice guidelines for surgical patients receiving MOUDs

Adequate support needed to address Canada's rising youth opioid use

Research shows a decline in opioid dispensing across Canadian provinces

Excess mortality associated with chronic pain can be avoided through spinal cord stimulation

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Pain News and Research

Latest Pain News and Research

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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