Pain News and Research

Latest Pain News and Research

Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

A clinical trial of an experimental drug for treatment-resistant major depression finds that modulation of the endogenous opioid system may improve the effectiveness of drugs that target the action of serotonin and related monoamine neurotransmitters.

12 Feb 2016

Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter and year ended December 31, 2015.

12 Feb 2016

Yale Cancer Center researchers identify cause of myeloma

Yale Cancer Center researchers have identified what causes a third of all myelomas, a type of cancer affecting plasma cells. The findings, published in the Feb. 11 issue of the New England Journal of Medicine, could fundamentally change the way this cancer and others are treated.

11 Feb 2016

Enhancing quality of life for people with serious illnesses

Being diagnosed with a potentially life-threatening illness is distressing enough but a dearth of cohesive services often compounds the difficulty, according to an NAU researcher.

11 Feb 2016

Vinegar could help fight ulcerative colitis

Vinegar is the perfect ingredient for making tangy sauces and dressings. Now, researchers report in ACS' Journal of Agricultural and Food Chemistry that the popular liquid could also help fight ulcerative colitis, an inflammatory bowel disease that research suggests is related to the gut microbiome.

11 Feb 2016

Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

New research uncovers a cascade of reactions within nerve cells that relay sensations of pain associated with inflammation. The findings, which are published in the British Journal of Pharmacology, indicate that drugs designed to curb this pathway may help relieve inflammatory pain in sufferers.

11 Feb 2016

Cranberry capsules more effective in lowering UTI risk than juice

A UTI is an infection in any part of the urinary system, kidneys, bladder or urethra. They are more common in women and affect more than 3 million Americans per year. Many in the population will turn to sipping on a cranberry juice cocktail to alleviate their symptoms, but, according to a Texas A&M Health Science Center urologist, drinking cranberry juice to treat a UTI is little more than an old wives' tale.

10 Feb 2016

Mayo Clinic researchers discover new bacterial species that triggers Lyme disease in people

Mayo Clinic researchers, in collaboration with the Centers for Disease Control and Prevention and health officials from Minnesota, North Dakota and Wisconsin, have discovered a new bacterial species that causes Lyme disease in people. The new species has been provisionally named Borrelia mayonii. Prior to this finding, the only species believed to cause Lyme disease in North America was Borrelia burgdorferi.

9 Feb 2016

Patients with COPD show decreased gray matter volume in certain areas of the brain

Chronic Obstructive Pulmonary Disease (COPD), a condition impacting nearly 24 million Americans, is often associated with disease-specific fears and avoidance of physical activity. Little is known of the structural brain processes that occur in COPD patients. A study published in the February issue of the journal CHEST found that patients with COPD demonstrated gray matter decreases in areas of the brain that process breathlessness, fear and sensitivity to pain.

9 Feb 2016

Taste deficits appear to be more prevalent in MS patients

Taste deficits appear to be more prevalent among multiple sclerosis (MS) patients than previously reported and correlate with brain lesions left by the debilitating disease, a new study from the University of Pennsylvania's Smell and Taste Center and the department of Radiology found.

9 Feb 2016

Wayne State inks exclusive license agreement with TRImaran Pharma for novel class of drugs

Wayne State University recently entered into an exclusive license agreement with TRImaran Pharma Inc. for a class of novel drugs developed at Wayne State University that aims to offer hope in the treatment of post-traumatic stress disorders (PTSD), depression, ADHD and other neurological disorders.

9 Feb 2016

New evidence highlights benefits and harms of using artificial mesh for surgical repair of vaginal prolapse

New evidence published today highlights benefits and harms of using artificial mesh when compared with tissue repair in the surgical treatment of vaginal prolapse. Slightly better repair with mesh needs to be weighed carefully against increased risk of harms.

9 Feb 2016

New pain management strategies key to maximizing patient outcomes after TKR procedures

According to a new literature review in the February issue of the Journal of the American Academy of Orthopaedic Surgeons, a team-based care approach (consisting of the patient, family members, the orthopaedic surgeon and other medical practitioners) on total knee replacement (TKR) procedures, in conjunction with newer pain management strategies, is key to maximizing patient outcomes.

9 Feb 2016

Effective treatments for knee instability may help reduce falls in older adults

Symptoms of knee instability in older adults may indicate an increased risk of falling and of experiencing the various physical and psychological effects that can result from falling, according to a study published in Arthritis Care & Research, a journal of the American College of Rheumatology.

8 Feb 2016

Better quality of care may reduce mortality risk in patients treated with opioid therapy for pain

Better quality of care may reduce the risk of death for patients who are prescribed opioid painkillers for chronic pain, say Yale researchers. Their study, published Feb. 4 in the Journal of General Internal Medicine, offers evidence that supports recommendations from clinical practice guidelines encouraging physicians to engage patients with mental health services and substance abuse treatment, as well as to avoid co-prescriptions for sedatives.

5 Feb 2016

Discovery takes researchers one step closer to preventing C. diff

Exposure to specific antibiotics is linked to the development of certain strains of antibiotic-resistant C. difficile, one of the fastest growing bacteria superbugs, according to a new study published by Stuart Johnson, MD, of Loyola University Health System, Loyola University Chicago Stritch School of Medicine and the Hines VA Medical Hospital.

5 Feb 2016

Meditation reduces anxiety, pain and fatigue in women undergoing breast cancer biopsies

Meditation eases anxiety, fatigue and pain for women undergoing breast cancer biopsies, according to researchers at the Duke Cancer Institute. They also found that music is effective, but to a lesser extent.

5 Feb 2016

Noninvasive FMRI may help evaluate effectiveness of new pain medications

New research may allow new, more effective and safer pain medications to reach patients who suffer from chronic pain sooner. According to a recent study published in Anesthesiology, the official medical journal of the American Society of Anesthesiologists, using functional magnetic resonance imaging (FMRI), to measure the brain's neural response to pain, may be a viable tool for evaluating the effectiveness of new pain medications during the early stages of human drug development - providing the needed objective evidence to prevent the premature discarding of potentially beneficial therapies.

4 Feb 2016

Prevalence of past-year generalized anxiety disorder much higher among older adults with COPD

The prevalence of past-year generalized anxiety disorder (GAD) for adults aged 50 and older with chronic obstructive pulmonary disease (COPD) is much higher compared to older adults without COPD (5.8% vs 1.7%), according to a new study published by University of Toronto researchers.

4 Feb 2016

NICE recommends Xofigo (radium-223 dichloride) for prostate cancer patients after treatment with docetaxel

The National Institute for Health and Care Excellence has issued its final guidance recommending Xofigo for use on the NHS in England and Wales as an option for treating adult men, with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastases, who have received previous docetaxel therapy.

4 Feb 2016

Pain News and Research

Latest Pain News and Research

Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

Yale Cancer Center researchers identify cause of myeloma

Enhancing quality of life for people with serious illnesses

Vinegar could help fight ulcerative colitis

Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

Cranberry capsules more effective in lowering UTI risk than juice

Mayo Clinic researchers discover new bacterial species that triggers Lyme disease in people

Patients with COPD show decreased gray matter volume in certain areas of the brain

Taste deficits appear to be more prevalent in MS patients

Wayne State inks exclusive license agreement with TRImaran Pharma for novel class of drugs

New evidence highlights benefits and harms of using artificial mesh for surgical repair of vaginal prolapse

New pain management strategies key to maximizing patient outcomes after TKR procedures

Effective treatments for knee instability may help reduce falls in older adults

Better quality of care may reduce mortality risk in patients treated with opioid therapy for pain

Discovery takes researchers one step closer to preventing C. diff

Meditation reduces anxiety, pain and fatigue in women undergoing breast cancer biopsies

Noninvasive FMRI may help evaluate effectiveness of new pain medications

Prevalence of past-year generalized anxiety disorder much higher among older adults with COPD

NICE recommends Xofigo (radium-223 dichloride) for prostate cancer patients after treatment with docetaxel

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

Pain News and Research

Latest Pain News and Research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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