Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

EvoGenix expands capabilities through US acquisition

EvoGenix and Absalus own complementary technologies which, when combined, are capable of streamlining the identification of new antibody drug candidates and improving the development of safe and effective human therapeutic antibodies.

4 Apr 2005

Mutations in the HFE gene directly associated with chronic joint disease

Mutations in the HFE gene, which is involved in iron regulation, seem to be directly associated with chronic joint disease (or haemophilic arthropathy) among haemophilic patients, claim a team of Portuguese scientists in the April issue of the journal Blood.

4 Apr 2005

Tumour Necrosis Factor alpha (TNF-alpha) blocking agents cause skin disease

Members of the second most important family of drugs used to treat rheumatoid arthritis can cause serious dermatological conditions in a quarter of patients under treatment, reveals a study published in the journal Arthritis Research and Therapy.

3 Apr 2005

Discovery of gene STAT6(B) may lead to new treatments for inflammatory diseases

In a paper featured in Proceedings of the National Academy of Science (PNAS), researchers from Boston University School of Dental Medicine report the discovery of a new gene, STAT6(B), that helps regulate production of the potentially deadly tumor necrosis factor alpha (TNF-alpha) cytokine.

28 Mar 2005

How does the body keep the number of neutrophils produced constant in the blood?

Every day, the human body manufactures and destroys about 100 billion neutrophils- the most common type of white blood cell and one of the most highly-produced cells. Neutrophils live about eight hours, are bacteria-eaters and are a key component of the immune system. Without them, the body can be subject to life-threatening infection.

23 Mar 2005

Scientists have found genetic regions that, when defective, allow the immune system to attack the pancreas

Scientists at Joslin Diabetes Center have found genetic regions that, when defective, allow the immune system to attack the pancreas -- the first in a series of mis-steps that lead to type 1 diabetes. Armed with these findings, published yesterday, March 22, in the journal Immunity, the researchers are now trying to hone in on the exact genes involved, in mice and in human patients.

23 Mar 2005

Inflammation is a strong risk factor for cardiovascular disease among rheumatoid arthritis patients

Mayo Clinic epidemiologists have found that the systemic inflammation characterizing rheumatoid arthritis may be to blame for the increased risk of cardiovascular death in patients with the disease.

3 Mar 2005

Cigarette smokers have an increased risk of experiencing rotator cuff tears

Cigarette smokers have an increased risk of experiencing rotator cuff tears in their shoulders than their tobacco-free counterparts, according to study results presented today at the 72nd Annual Meeting of the American Academy of Orthopaedic Surgeons.

27 Feb 2005

Discovery could lead to the prevention, and possibly treatment of autoimmune diseases such as Type 1 diabetes

Scientists at the University of Maryland School of Medicine in Baltimore have identified a way to prevent Type I diabetes in rats that are genetically prone to develop the disease.

23 Feb 2005

Lack of collagen increases likelihood of osteoarthritis

Duke University Medical Center researchers have found that joints whose cartilage lacks a specific type of collagen will develop osteoarthritis – the so-called "wear-and-tear" form of the disease – at a greatly accelerated rate.

20 Feb 2005

Renovis announces investigational medicine for multiple sclerosis study

Renovis announced today the initiation of a Phase Ia clinical trial for REN-850, an investigational oral small molecule that is being targeted for the treatment of multiple sclerosis (MS).

14 Feb 2005

Asthma or allergies in an expectant mother may increase the likelihood that her child will exhibit symptoms of autism

This association between a mother's asthma and allergies and a child's autism has not been reported in the medical literature previously, says Dr. Croen, and requires replication in further studies.

7 Feb 2005

Rheumatoid arthritis linked to excess risk of congestive heart failure

A serious chronic disease, rheumatoid arthritis (RA) is characterized by inflammation and damage of the joint, major organ involvement and increased mortality. Among patients, about one in three deaths results from cardiovascular disease (conditions affecting the heart or blood vessels).

3 Feb 2005

People with rheumatoid arthritis have more silent, unrecognized heart attacks and sudden cardiac deaths

People with rheumatoid arthritis not only have a higher risk of coronary heart disease than those in the general population, but they have more silent, unrecognized heart attacks and sudden cardiac deaths, according to a Mayo Clinic study published in the February issue of Arthritis & Rheumatism.

3 Feb 2005

Enbrel to treat rheumatoid arthritis approved in Japan

Wyeth K.K. and Takeda Pharmaceutical Company Limited (Takeda) have announced that Enbrel (etanercept) has been approved by the Japan Ministry of Health, Labour and Welfare (MHLW) for the treatment of rheumatoid arthritis (RA) in patients who had an inadequate response to existing therapies.

27 Jan 2005

Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition

A Johns Hopkins-led study designed to evaluate the ability of etanercept to maintain disease remissions in a serious autoimmune disorder has failed to show any benefit. Etanercept, also called Enbrel, is a common treatment for rheumatoid arthritis and other types of joint inflammation.

26 Jan 2005

Monoclonal antibody therapeutics to fill vacuum left by ineffective conventional therapies

Currently, the limited efficacy of conventional therapies, especially in the case of several oncology and autoimmune and inflammatory disorders (AIID), is creating the need for safe and effective treatment alternatives.

25 Jan 2005

Promising new evidence for the optimal use of biologic therapies for rheumatoid arthritis

A major cause of pain and disability, rheumatoid arthritis (RA) is also potentially the most treatable form of chronic arthritis. Researchers, doctors, and patients agree that a group of drugs called disease-modifying antirheumatic drugs (DMARDs) can effectively reduce joint pain and stiffness.

7 Jan 2005

Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein

Aggressive therapy with statins -- drugs that inhibit cholesterol synthesis -- works better than moderate statin therapy in reducing fats and proteins in the blood that have been linked to atherosclerosis, a new multi-center study concludes. Statins’ effects on both complex compounds appear beneficial in cutting patients’ cardiovascular risks.

6 Jan 2005

Chronic users NSAIDs have greater risk of bleeding and visible damage to their small intestine

According to a study published today in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, chronic users of non-steroidal anti-inflammatory drugs (NSAIDs) have an increased risk of bleeding and visible damage to their small intestine.

4 Jan 2005

Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

EvoGenix expands capabilities through US acquisition

Mutations in the HFE gene directly associated with chronic joint disease

Tumour Necrosis Factor alpha (TNF-alpha) blocking agents cause skin disease

Discovery of gene STAT6(B) may lead to new treatments for inflammatory diseases

How does the body keep the number of neutrophils produced constant in the blood?

Scientists have found genetic regions that, when defective, allow the immune system to attack the pancreas

Inflammation is a strong risk factor for cardiovascular disease among rheumatoid arthritis patients

Cigarette smokers have an increased risk of experiencing rotator cuff tears

Discovery could lead to the prevention, and possibly treatment of autoimmune diseases such as Type 1 diabetes

Lack of collagen increases likelihood of osteoarthritis

Renovis announces investigational medicine for multiple sclerosis study

Asthma or allergies in an expectant mother may increase the likelihood that her child will exhibit symptoms of autism

Rheumatoid arthritis linked to excess risk of congestive heart failure

People with rheumatoid arthritis have more silent, unrecognized heart attacks and sudden cardiac deaths

Enbrel to treat rheumatoid arthritis approved in Japan

Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition

Monoclonal antibody therapeutics to fill vacuum left by ineffective conventional therapies

Promising new evidence for the optimal use of biologic therapies for rheumatoid arthritis

Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein

Chronic users NSAIDs have greater risk of bleeding and visible damage to their small intestine

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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