Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

New treatment approach for severe asthma

Researchers have uncovered a potentially new treatment approach for severe asthma, by blocking a powerful immune system chemical, present in large amounts in patients with the severe form of the disease, a small study in Thorax reveals.

20 Sep 2005

Drug AMD-3100 may help cancer patients who need stem cell transplants

A new drug may help cancer patients mobilize the cells necessary to restore their blood-forming system after high-dose chemotherapy, according to results from a clinical trial at the Kimmel Cancer Center at Thomas Jefferson University Hospital in Philadelphia and at other centers across the nation.

19 Sep 2005

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

A major finding by researchers at the La Jolla Institute for Allergy & Immunology (LIAI) has identified a previously unknown cellular mechanism that acts as an off switch for immune system function.

12 Sep 2005

Nuclear receptor proteins could change anti-inflammatory treatments

Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).

12 Sep 2005

Recent evidence suggests caution in prescribing hormone therapy for breast cancer

One of the most effective new treatments for breast cancer is a hormone therapy. Aromatase inhibitors work by powerfully blocking the conversion of androgen precursors into estrogens, which lowers estradiol levels in the bloodstream and estrogen levels in peripheral tissues.

4 Sep 2005

Is the disease course of rheumatoid arthritis becoming milder?

Rheumatoid arthritis (RA) is a chronic inflammatory disease, marked with joint pain and erosion. The course of RA can vary considerably, from mild to crippling, and is difficult to predict.

4 Sep 2005

Pomegranate fruit extracts can block enzymes that contribute to osteoarthritis

The study looked at the ability of an extract of pomegranate fruit against Interleukin-1b (IL-1b), a pro-inflammatory protein molecule that plays a key role in cartilage degradation in osteoarthritis.

1 Sep 2005

Disease modifying activity of 2ME2 demonstrated in preclinical rheumatoid arthritis studies

EntreMed a clinical-stage pharmaceutical company developing therapeutics primarily for the treatment of cancer and inflammatory diseases, has announced the presentation of positive preclinical results for its lead compound, 2-methoxyestradiol (2ME2), in models of rheumatoid arthritis.

24 Aug 2005

Patients with primary biliary cirrhosis who are treated with methotrexate have an increased risk of death

In five randomized controlled trials involving 457 people, the authors report that for patients treated with methotrexate, as a single therapy or in combination with other drug treatment, pooled data showed a tendency toward an increased risk of death or liver transplantation. The brand names for methotrexate are Rheumatrex and Trexall.

23 Aug 2005

New research says brightly-coloured fruit and veggies protects against arthritis

Apparently rheumatoid arthritis currently affects around 1% adults in the UK, and previous studies have suggested that vitamin C and the pigment beta-cryptoxanthin, both of which are found in brightly-coloured fruit and vegetables, may act as antioxidants, and protect the body against the oxidative damage which can cause inflammation.

22 Aug 2005

Brightly-coloured fruit and veg, may act as antioxidants - protect against rheumatoid arthritis

Rheumatoid arthritis currently affects around 1% adults in the UK. Previous studies have suggested that vitamin C and the pigment beta-cryptoxanthin, both of which are found in brightly-coloured fruit and veg, may act as antioxidants, and protect the body against the oxidative damage which can cause inflammation.

From The University of Manchester 17 Aug 2005

Discovery of gene that controls the speed at which patients develop tuberculosis

Scientists at the Research Institute of the McGill University Health Centre (RI MUHC) have discovered a gene that controls the speed at which patients develop tuberculosis--the first time such a gene has been discovered for this disease.

16 Aug 2005

New hope for those deaf from immune system attack

A new study may one day help those deafened by immune system attack, and possibly also lead to a test that could show which patients may be helped by immediate steroid treatment.

16 Aug 2005

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

For people with long-standing rheumatoid arthritis, combined treatment with the new "biologic" drug adalimumab and methotrexate is about five times more effective than methotrexate alone, according to a new systematic review of studies.

15 Aug 2005

Abbott receives European approval to market Humira

Abbott has announced that it has received approval from the European Commission to market Humira (adalimumab) as a treatment for psoriatic arthritis and early rheumatoid arthritis (RA) in Europe.

15 Aug 2005

Scientists discover how an HIV protein fragment shuts down an immune response

The HIV virus hides out in the very immune system cells that are meant to protect the body from viral infection. But how does it prevent these cells from mounting a full-scale attack against the invader?

11 Jul 2005

Patients with rheumatoid arthritis are at increased risk of coronary artery disease

The findings of research published today in Arthritis Research & Therapy show that CAD is accelerated in RA patients, and patients with both RA and CAD are at an increased risk of death from heart disease.

28 Jun 2005

Enzyme known as cathepsin G may be a target for anti-inflammatory treatments

The finding by researchers at Washington University School of Medicine in St. Louis shows that an enzyme known as cathepsin G regulates the ability of immune cells known as neutrophils to secrete chemicals that attract other immune cells and start the local inflammatory process. Over time, the excessive accumulation of immune cells can lead to tissue and cartilage damage in joints, causing pain and limiting mobility.

27 Jun 2005

Expression profiles and functional analyses of Wnt-related genes in human joint disorders

The cellular signaling protein Wnt, which is involved in embryonic development and cancer, contributes to disease progression of both rheumatoid arthritis and osteoarthritis.

26 Jun 2005

Immunomedics awarded U.S. and Australian patents

Immunomedics announced that it has received notices that the U.S. and Australian patent offices have allowed claims in respective patent applications covering methods for treating a wide range of autoimmune diseases using monoclonal antibodies that bind to the CD22 antigen present on B-lymphocytes.

16 Jun 2005

Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

New treatment approach for severe asthma

Drug AMD-3100 may help cancer patients who need stem cell transplants

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

Nuclear receptor proteins could change anti-inflammatory treatments

Recent evidence suggests caution in prescribing hormone therapy for breast cancer

Is the disease course of rheumatoid arthritis becoming milder?

Pomegranate fruit extracts can block enzymes that contribute to osteoarthritis

Disease modifying activity of 2ME2 demonstrated in preclinical rheumatoid arthritis studies

Patients with primary biliary cirrhosis who are treated with methotrexate have an increased risk of death

New research says brightly-coloured fruit and veggies protects against arthritis

Brightly-coloured fruit and veg, may act as antioxidants - protect against rheumatoid arthritis

Discovery of gene that controls the speed at which patients develop tuberculosis

New hope for those deaf from immune system attack

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

Abbott receives European approval to market Humira

Scientists discover how an HIV protein fragment shuts down an immune response

Patients with rheumatoid arthritis are at increased risk of coronary artery disease

Enzyme known as cathepsin G may be a target for anti-inflammatory treatments

Expression profiles and functional analyses of Wnt-related genes in human joint disorders

Immunomedics awarded U.S. and Australian patents

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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