Serotonin News and Research

Latest Serotonin News and Research

Post-COVID depressive symptoms respond well to antidepressants, study shows

The COVID pandemic has led to a significant increase in mental health problems. Now, in some good news, a pilot study has shown that depressed patients who have suffered from COVID respond better to standard antidepressants than do people who have not had COVID.

4 Oct 2021

Existing drug used to treat constipation may boost people's ability to think more clearly

The development of drugs to treat cognitive problems in patients with mental illness may be a step closer after a team of researchers discovered that an existing drug - used to treat constipation - may be able to boost our ability to think more clearly.

4 Oct 2021

Study finds genetic link between driving convictions, accidents and everyday behavior

A new long-term psychological study of drivers has found an association between driving convictions, accidents and everyday behavior such as eating junk food or alcohol consumption.

3 Oct 2021

Researchers explore the clinical use of intravenous infusions of ketamine to treat depression

Depression is the most common mental illness as well as the number one cause of disability among people between the ages of 15 and 44. And for millions of sufferers, antidepressants have literally saved lives that could otherwise have been lost to suicide.

29 Sep 2021

Classic antidepressants show potential to enhance modern cancer treatments

Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term.

28 Sep 2021

Research paves the way for advances in the treatment of many brain disorders

Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.

16 Sep 2021

Drug accumulation alters gut bacterial metabolism and composition

In a research paper recently published in the journal Nature by Klünemann et al. (September 8th, 2021), the interaction of 15 diverse drugs with 25 common strains of gut bacteria is investigated, revealing 70 bacteria-drug interactions that include 29 entirely novel mechanisms not yet reported.

15 Sep 2021

Elevated levels of serotonin can curb cocaine addiction in mice

Elevated levels of serotonin can prevent the development of compulsive cocaine seeking and addiction in mice, researchers report.

13 Sep 2021

Neuroscientists reveal brain mechanism related to how serotonin controls cocaine addiction

Contrary to common thinking, cocaine triggers an addiction only in 20% of the consumers. But what happens in their brains when they lose control of their consumption? Thanks to a recent experimental method, neuroscientists at the University of Geneva, Switzerland, have revealed a brain mechanism specific to cocaine, which has the particularity of triggering a massive increase in serotonin in addition to the increase in dopamine common to all drugs.

12 Sep 2021

Study finds SARS-CoV-2 affects the brain by binding with MAO enzymes

A new study by researchers in Croatia and Slovenia shows the SARS-CoV-2 spike protein has an affinity towards monoamine oxidases (MAO) enzymes. Changes in MAO levels have been the culprit for several neuropsychiatric disorders such as Parkinson’s or Alzheimer’s disease.

6 Sep 2021

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Oncotarget published "Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis" which reported that microscopic imaging, immunocytochemistry, wound healing assay, caspase-cleaved cytokeratin 18 CytoDeath ELISA assay, immunofluorescence labeling assays for apoptosis, hypoxia, Western Blotting, Tunnel assay, measurement of 5-HT secretion by carbon fiber amperometry assay, quantitative methylation-specific PCR, morphologic changes, cell viability, apoptosis activity and the expression levels of phospho-Akt1, Akt1, HIF-1α, PI3K, p21, CAIX, 5-HT, phospho-mTOR, and mTOR in xenografts derived from typical H727 and atypical H720 BC cell lines.

28 Aug 2021

FDA-approved antiplatelet drug shows potential as new, low-cost heart failure therapy

Sarpogrelate, an antiplatelet medication, has potential as a new heart failure therapy and, according to researchers, could potentially decrease health care costs associated with cardiovascular disease, according to preliminary animal research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2021.

23 Aug 2021

Research shines light on histamine as a potential key player in depression

Bodily inflammation dampens levels of a ‘feel-good molecule’ and antidepressants’ ability to boost them, according to new research in mice.

17 Aug 2021

Women say California insurer makes it too hard to get drug for postpartum depression

When Miriam McDonald decided she wanted to have another baby at age 44, her doctor told her she had a better chance of winning the lottery. So when she got pregnant right away, she and her husband were thrilled. But within three days of giving birth to their son, in September 2019, everything shifted.

28 Jul 2021

Investigational antipsychotic treatment offers sustained benefits for people with dementia-related psychosis

Evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis has been published.

22 Jul 2021

Gene therapy delivered into the brain may be safe, effective in treating rare neurological disorder

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

16 Jul 2021

Novel method of gene therapy promises to transform the treatment of rare genetic disorder

A novel method of gene therapy is helping children born with a rare genetic disorder called AADC deficiency that causes severe physical and developmental disabilities.

12 Jul 2021

Non-toxic derivative of tetanus neurotoxin may help treat depression, neurodegenerative diseases

Depression has been treated traditionally with inhibitors of serotonin reuptake in the central nervous system.

9 Jul 2021

Prenatal THC and CBD exposure impairs offspring's ability to respond to fluoxetine

Scientists at Indiana University have found that significant amounts of the two main components of cannabis, THC and CBD, enter the embryonic brain of mice in utero and impair the mice's ability as adults to respond to fluoxetine, a drug commonly used to treat anxiety and depression and known by the brand name Prozac.

1 Jul 2021

Declining sense of smell among older adults is more complex than previously believed

Contrary to what science once suggested, older people with a declining sense of smell do not have comprehensively dampened olfactory ability for odors in general - it simply depends upon the type of odor.

1 Jul 2021

Serotonin News and Research

Latest Serotonin News and Research

Post-COVID depressive symptoms respond well to antidepressants, study shows

Existing drug used to treat constipation may boost people's ability to think more clearly

Study finds genetic link between driving convictions, accidents and everyday behavior

Researchers explore the clinical use of intravenous infusions of ketamine to treat depression

Classic antidepressants show potential to enhance modern cancer treatments

Research paves the way for advances in the treatment of many brain disorders

Drug accumulation alters gut bacterial metabolism and composition

Elevated levels of serotonin can curb cocaine addiction in mice

Neuroscientists reveal brain mechanism related to how serotonin controls cocaine addiction

Study finds SARS-CoV-2 affects the brain by binding with MAO enzymes

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

FDA-approved antiplatelet drug shows potential as new, low-cost heart failure therapy

Research shines light on histamine as a potential key player in depression

Women say California insurer makes it too hard to get drug for postpartum depression

Investigational antipsychotic treatment offers sustained benefits for people with dementia-related psychosis

Gene therapy delivered into the brain may be safe, effective in treating rare neurological disorder

Novel method of gene therapy promises to transform the treatment of rare genetic disorder

Non-toxic derivative of tetanus neurotoxin may help treat depression, neurodegenerative diseases

Prenatal THC and CBD exposure impairs offspring's ability to respond to fluoxetine

Declining sense of smell among older adults is more complex than previously believed

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Serotonin News and Research

Latest Serotonin News and Research

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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