Serotonin News and Research

Latest Serotonin News and Research

Use of a common type of antidepressant may increase gastrointestinal (GI) bleeding

In fact, the study suggests that the increase is similar to that associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs, known as pain relievers). DDW is the largest international gathering of physicians, academics and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

17 May 2005

St. John's Wort only minimally effective in relieving major depression

St. John’s Wort, the herbal medicinal long thought to relieve symptoms of depression, provides only minor benefits in patients with the most acute depression and perhaps no benefit for those with chronic depression.

16 May 2005

Fat-fighting drugs may be a far riskier business than they seem

Experts are warning that despite the fact that obesity is one of the biggest preventable causes of death, fat-fighting drugs may be a far riskier business than they seem, particularly for investors.

11 May 2005

Clues about how alcoholic behavior is “switched” on

As part of an ongoing effort to understand the biochemical basis of alcohol abuse, scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have published two studies on how modulating receptors for dopamine - a chemical “signaler” in the brain’s reward circuits - affects drinking behavior in mice and rats.

9 May 2005

Suspect gene may increase susceptibility to anxiety and depression

People with the depression-linked gene variant showed less gray matter and weaker connections in the mood-regulating circuit. How well the circuit was connected accounted for nearly 30 percent of their anxious temperament

8 May 2005

Psychological treatment most effective treatment for pediatric obsessive-compulsive disorder

Psychological treatment that teaches children to face their fears is the most effective treatment for pediatric obsessive-compulsive disorder (OCD), according to a new Mayo Clinic analysis of previously published research.

4 May 2005

Direct-to-consumer advertising may influence physicians' prescribing decisions

Patients requesting specific medications can have a profound effect on physicians prescribing medications for major depression, according to a new study in the April 27 issue of JAMA.

26 Apr 2005

EU calls for tougher warnings on antidepressants for kids

A committee of experts in Europe are calling for strong warnings to be placed on two classes of antidepressants, informing doctors and parents of the risk they could pose to children and adolescents.

25 Apr 2005

Brain-injury rehabilitation depends on acetylcholine circuitry

The ability of the brain to recover from such injury as stroke or trauma depends on a particular circuitry of neurons that "talk" to one another using the brain chemical acetylcholine, researchers led by James Conner and Mark Tuszynski in the Neural repair Group at UCSD have discovered.

20 Apr 2005

A parent's weight may also play a role in adolescent weight gain

The prevalence of adolescent obesity has doubled over the last 30 years and can lead to serious medical problems, like high blood pressure, diabetes, cardiovascular disease and colorectal cancer.

11 Apr 2005

Study may lead to a better understanding of how antidepressants like Prozac work

According to results published in today's issue of the journal Neuron, a study in mice proposes that dopamine and serotonin neurotransmitter systems in the brain occasionally get their signals crossed, causing delays in stabilizing mood.

7 Apr 2005

SSRI antidepressants "hijack" dopamine signaling as well launching serotonin signals

Researchers have discovered that antidepressant drugs such as Prozac not only affect levels of the neurotransmitter serotonin in the brain, but also "hijack" dopamine signaling as well--causing it to launch serotonin signals. Their findings offer new insight into how Prozac and other "selective serotonin uptake inhibitors" (SSRIs) work and how they might cause problems in patients taking them.

6 Apr 2005

Metabolic side effects of antipsychotics are known, but rarely monitored

Psychiatrists are doing a “modest” job of monitoring for weight gain, diabetes and other metabolic problems that may result from use of the newer antipsychotics for schizophrenia, researchers say.

5 Apr 2005

Could NAADP/cholecystokinin-combo attack fat from inside and out?

One traditional approach to pharmaceutical design uses so-called “first messengers” – hormones, other natural facilitators or synthetic products – to initiate various cellular cascades for the desired physiological effect. To date, despite concerted efforts at all levels of research, this approach has failed to develop a truly successful obesity drug to address this major global health problem.

3 Apr 2005

Drugs alone are not enough for fighting obsessions and compulsions

Both medication and psychotherapy are effective in obsessive-compulsive disorder (OCD). However, they both have disadvantages. A group of researchers at the La Sapienza University studied the long-term effectiveness of integrated treatment compared with medication alone.

21 Mar 2005

Antidepressants not the culprit in depression linked to heart attacks

The increased risk of heart attack associated with taking antidepressants may be caused by the depression itself rather than the drugs themselves, suggests new research reported in the current issue in the British Medical Journal. At least one in 10 older people are prescribed antidepressants.

15 Mar 2005

Second-generation Antidepressants

A recent article in the prestigious British Medical Journal seems to confirm an increased risk for suicidal behavior among adults taking popular antidepressants. This follows evidence that certain selective serotonin reuptake inhibitors (SSRIs) may have a similar effect among children and adolescents.

27 Feb 2005