Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Higher prevalence of anxiety disorders in youth with chronic medical conditions

Youth who report one of the seven chronic medical conditions (CMCs), including asthma, congenital heart disease, diabetes, epilepsy, inflammatory bowel disease, juvenile idiopathic arthritis, and sickle cell disease, are often diagnosed with an anxiety disorder.

4 May 2020

Rice University wins prestigious grant to develop new therapies for sickle cell disease

A Rice University lab has won a prestigious National Institutes of Health grant to pursue gene-editing research it hopes will lead to a cure for sickle cell disease (SCD).

25 Apr 2020

Exploring mechanisms of resistance to HIV in people with sickle cell disease

Analysis supports reports that sickle cell disease causes lower HIV infection rate, but cell studies did not reveal a mechanism.

8 Apr 2020

Study underscores the need for more precise rare disease definitions

Some diseases are like black swans. They occur so rarely that many physicians never encounter them in their clinical practice, complicating efforts to treat them.

5 Feb 2020

Certain enzymes implicated in diseases like cancer also destroy each other

Like motley bandits, certain enzymes implicated in cancer and other diseases also annihilate each other. A new study reveals details of their mutual foils in the hopes that these behaviors can be leveraged to fight the enzymes' disease potential.

20 Jan 2020

Enzymes that cannibalize each other and promote cancer

A new study to be published this week in the journal The Proceedings of the National Academy of Sciences in the week of January 20, 2020. shows that certain human enzymes play dual roles in health and disease. Not only do they promote the occurrence of cancer and some other illnesses, they also eliminate one another rather like cannibals. The researchers hope this behaviour can be exploited to prevent these enzymes from causing human disease.

20 Jan 2020

Effort to control opioids in an ER leaves some sickle cell patients in pain

India Hardy has lived with pain since she was a toddler — ranging from dull persistent aches to acute flare-ups that interrupt the flow of her normal life.

6 Jan 2020

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

A new study led by the Sainte-Justine University Hospital Centre and the University of Montreal, along with the Washington University School of Medicine in St. Louis, has found that transfusions using fresh red blood cells--cells that have spent seven days or less in storage--are no more beneficial than older red blood cells in reducing the risk of organ failure or death in critically ill children.

10 Dec 2019

Identifying the type of pain in adults with sickle cell disease may help improve treatment

Identifying the type of pain an adult with sickle cell disease experiences may be useful in improving treatment, according to a new study by researchers at Yale Cancer Center and Smilow Cancer Hospital.

8 Dec 2019

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a new study in the Nature journal Communications Biology describes a new innovation that could accelerate this work by rapidly revealing unintended and potentially harmful changes introduced by a gene editing process.

6 Dec 2019

Prenatal screening for hemoglobinopathies different in OBGYN practices and family medicine

Sickle cell disease is one of the most common inherited red blood cell disorders, yet many are not aware of their carrier status (Treadwell, J Nat Med Assoc, 2006), which can lead to confusion around pregnancy and newborn diagnosis.

5 Dec 2019

Pharma’s take on the Pelosi drug-pricing bill: Fair warning or fearmongering?

House Speaker Nancy Pelosi's flagship proposal to curb prescription drug prices, the "Lower Drug Costs Now Act" - H.R. 3 - could come up for a vote in the chamber this month.

5 Dec 2019

New project could mark a pivotal advancement in therapies to address male sterility

Researchers from the University of Georgia, Emory University School of Medicine and the University of Pittsburgh have received a $2.9 million grant from the National Institutes of Health to test a novel method of producing viable sperm cells from skin cells.

3 Dec 2019

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Along with the promise that CRISPR-Cas9 gene editing technology can offer new human therapies is the need to ensure its safety. A recent study showed that CRISPR-Cas9 did not produce off-target gene mutations in zebrafish. These results, published in Frontiers in Genetics, confirm previous data in animal models that the risk to the rest of the genome from gene editing is minimal.

3 Dec 2019

NIH Statement for World AIDS Day outlines efforts to end the HIV epidemic

With World AIDS Day on 1st December, we are reminded by the NIH of the work that needs to be done to end the HIV Epidemic.

28 Nov 2019

Mystery surrounds gene edited babies one year on

A year back Chinese scientist He Jiankui was in the news for all the wrong reasons. He had helped create the world’s first genetically edited human babies. After a year the world is still in dark about the whereabouts and health of the babies he had created and he himself has been not seen since January this year.

27 Nov 2019

Carbon monoxide has a beneficial side at low concentrations

Most people think of carbon monoxide as harmful, and with good reason -- the colorless, odorless gas sends 50,000 people in the U.S. to hospitals each year when their furnaces malfunction or car engines run in poorly ventilated spaces. But at low concentrations, carbon monoxide has a beneficial side that scientists are trying to harness to treat diseases, according to an article in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society.

20 Nov 2019

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Higher prevalence of anxiety disorders in youth with chronic medical conditions

Rice University wins prestigious grant to develop new therapies for sickle cell disease

Exploring mechanisms of resistance to HIV in people with sickle cell disease

Study underscores the need for more precise rare disease definitions

Certain enzymes implicated in diseases like cancer also destroy each other

Enzymes that cannibalize each other and promote cancer

Effort to control opioids in an ER leaves some sickle cell patients in pain

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

Identifying the type of pain in adults with sickle cell disease may help improve treatment

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Prenatal screening for hemoglobinopathies different in OBGYN practices and family medicine

Pharma’s take on the Pelosi drug-pricing bill: Fair warning or fearmongering?

New project could mark a pivotal advancement in therapies to address male sterility

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

NIH Statement for World AIDS Day outlines efforts to end the HIV epidemic

Mystery surrounds gene edited babies one year on

Carbon monoxide has a beneficial side at low concentrations

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

Novartis announces strategy to broaden patient reach and availability of medicines in sub-Saharan Africa

Improved gene editing technique can successfully cut out undesirable genetic information

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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