Sickle Cell Disease

Sickle-cell disease, or sickle-cell anaemia (or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in a risk of various complications.
Understanding Sickle Cell Disease

World Sickle Cell Day is June 19 and was created by the United Nations in 2006 to raise global awareness for sickle cell disease as a public health problem. Sickle cell disease is an extremely debilitating medical condition.

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Overview

Feature Articles

Latest Sickle Cell Disease News and Research

New technique can help to non-invasively assess progression of sickle cell retinopathy

New technique can help to non-invasively assess progression of sickle cell retinopathy

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

California and Texas took different routes to vaccination. Who’s ahead?

California and Texas took different routes to vaccination. Who’s ahead?

Toward a transformative therapy for sickle cell patients

Toward a transformative therapy for sickle cell patients

Adaptive cognitive training program can benefit children with sickle cell disease

Adaptive cognitive training program can benefit children with sickle cell disease

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Researchers identify factors linked to poor outcomes in patients with childhood-onset lupus

Researchers identify factors linked to poor outcomes in patients with childhood-onset lupus

Research could lead to a personalized approach for treating sickle cell disease

Research could lead to a personalized approach for treating sickle cell disease

People with high BMI may now receive their COVID-19 vaccine in California

People with high BMI may now receive their COVID-19 vaccine in California

Combined liver-cytokine humanization enhances human red blood cell production and survival

Combined liver-cytokine humanization enhances human red blood cell production and survival

A single letter difference in a single gene spells a lifetime of anemia, pain worldwide

A single letter difference in a single gene spells a lifetime of anemia, pain worldwide

Differences in immune response to SARS-CoV-2 determine disease severity, study finds

Differences in immune response to SARS-CoV-2 determine disease severity, study finds

Study explains why people of African descent are less likely to find bone marrow donors

Study explains why people of African descent are less likely to find bone marrow donors

Enriched diet and companionship can reduce pain in mice with sickle cell disease

Enriched diet and companionship can reduce pain in mice with sickle cell disease

Researchers identify genetic risk factors contributing to pneumonia susceptibility and severity

Researchers identify genetic risk factors contributing to pneumonia susceptibility and severity

New taxonomic classification of non-skeletal rare congenital disorders with impact on bone physiology

New taxonomic classification of non-skeletal rare congenital disorders with impact on bone physiology

New toolkit aims to maximize high-quality collection of thrombosis data in COVID-19 clinical studies

New toolkit aims to maximize high-quality collection of thrombosis data in COVID-19 clinical studies

Detailed simulations reveal new information on sickle cell disease

Detailed simulations reveal new information on sickle cell disease

New diagnostic technology accurately tests for anemia, sickle cell disease

New diagnostic technology accurately tests for anemia, sickle cell disease