Sickle Cell Disease

Sickle-cell disease, or sickle-cell anaemia (or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in a risk of various complications.
Understanding Sickle Cell Disease

World Sickle Cell Day is June 19 and was created by the United Nations in 2006 to raise global awareness for sickle cell disease as a public health problem. Sickle cell disease is an extremely debilitating medical condition.

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Overview

Feature Articles

Latest Sickle Cell Disease News and Research

Oral prodrug delivers carbon monoxide to protect against acute kidney injury

Oral prodrug delivers carbon monoxide to protect against acute kidney injury

Most states did not use health equity committees to assist with COVID-19 vaccine distribution planning

Most states did not use health equity committees to assist with COVID-19 vaccine distribution planning

Citizens’ jury set to reflect deeply on the pros and cons of human genome editing

Citizens’ jury set to reflect deeply on the pros and cons of human genome editing

Global blood centers join hands to develop more efficient, accurate blood typing technology

Global blood centers join hands to develop more efficient, accurate blood typing technology

UCSF launches new initiative to propel the development of living therapeutics

UCSF launches new initiative to propel the development of living therapeutics

Johns Hopkins researcher receives prestigious award for breakthrough research in circadian science

Johns Hopkins researcher receives prestigious award for breakthrough research in circadian science

Pitt researchers use a unique and powerful MRI device to study sickle cell disease

Pitt researchers use a unique and powerful MRI device to study sickle cell disease

Researchers develop proof-of-concept treatment for blood disorders

Researchers develop proof-of-concept treatment for blood disorders

New technique can help to non-invasively assess progression of sickle cell retinopathy

New technique can help to non-invasively assess progression of sickle cell retinopathy

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

California and Texas took different routes to vaccination. Who’s ahead?

California and Texas took different routes to vaccination. Who’s ahead?

Toward a transformative therapy for sickle cell patients

Toward a transformative therapy for sickle cell patients

Adaptive cognitive training program can benefit children with sickle cell disease

Adaptive cognitive training program can benefit children with sickle cell disease

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Researchers identify factors linked to poor outcomes in patients with childhood-onset lupus

Researchers identify factors linked to poor outcomes in patients with childhood-onset lupus

Research could lead to a personalized approach for treating sickle cell disease

Research could lead to a personalized approach for treating sickle cell disease

People with high BMI may now receive their COVID-19 vaccine in California

People with high BMI may now receive their COVID-19 vaccine in California

Combined liver-cytokine humanization enhances human red blood cell production and survival

Combined liver-cytokine humanization enhances human red blood cell production and survival

A single letter difference in a single gene spells a lifetime of anemia, pain worldwide

A single letter difference in a single gene spells a lifetime of anemia, pain worldwide