Sickle Cell Disease

Sickle-cell disease, or sickle-cell anaemia (or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in a risk of various complications.
Understanding Sickle Cell Disease

World Sickle Cell Day is June 19 and was created by the United Nations in 2006 to raise global awareness for sickle cell disease as a public health problem. Sickle cell disease is an extremely debilitating medical condition.

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Overview

Feature Articles

Latest Sickle Cell Disease News and Research

Six-country African study highlights the potential dangers of getting COVID-19 during pregnancy

Six-country African study highlights the potential dangers of getting COVID-19 during pregnancy

Novel gene-based therapies for sickle cell disease rely on finding the right mouse for the job

Novel gene-based therapies for sickle cell disease rely on finding the right mouse for the job

Brigham receives $16 million Helmsley Charitable Trust grant to improve healthcare delivery for NCDs

Brigham receives $16 million Helmsley Charitable Trust grant to improve healthcare delivery for NCDs

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

New Stad Center for Pediatric Pain, Palliative & Integrative Medicine launched with a $3 million gift

New Stad Center for Pediatric Pain, Palliative & Integrative Medicine launched with a $3 million gift

Study highlights the economic burden affecting individuals with sickle cell disease

Study highlights the economic burden affecting individuals with sickle cell disease

Corticosteroid exposure associated with hospitalization for severe pain event among patients with sickle cell disease

Corticosteroid exposure associated with hospitalization for severe pain event among patients with sickle cell disease

Young adult men with sickle cell disease are unaware of SCD-associated fertility issues, study reveals

Young adult men with sickle cell disease are unaware of SCD-associated fertility issues, study reveals

UNSW research improves fundamental understanding of the mechanism behind sickle cell disease

UNSW research improves fundamental understanding of the mechanism behind sickle cell disease

Big pharma is betting on bigger political ambitions from Sen. Tim Scott

Big pharma is betting on bigger political ambitions from Sen. Tim Scott

Music therapy is beneficial for patients with sickle cell disease

Music therapy is beneficial for patients with sickle cell disease

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Health care costs for people with rare diseases have been underestimated, study shows

Health care costs for people with rare diseases have been underestimated, study shows

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Researchers seek to identify the role of hypoxia on red blood cell aging

Researchers seek to identify the role of hypoxia on red blood cell aging

Nemours receives $10.5 million NIH grant to support research in sickle cell disease

Nemours receives $10.5 million NIH grant to support research in sickle cell disease

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients