Sickle Cell Disease

Sickle-cell disease, or sickle-cell anaemia (or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in a risk of various complications.
Understanding Sickle Cell Disease

World Sickle Cell Day is June 19 and was created by the United Nations in 2006 to raise global awareness for sickle cell disease as a public health problem. Sickle cell disease is an extremely debilitating medical condition.

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Overview

Feature Articles

Latest Sickle Cell Disease News and Research

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

Majority of U.S. COVID-19 fatalities had underlying medical conditions

Majority of U.S. COVID-19 fatalities had underlying medical conditions

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

New research project receives federal funding to expand treatment options for sickle cell patients

New research project receives federal funding to expand treatment options for sickle cell patients

Cannabis could be a potentially effective treatment for sickle cell disease pain

Cannabis could be a potentially effective treatment for sickle cell disease pain

PCORI approves up to $50 million in funding for new projects to address COVID-19

PCORI approves up to $50 million in funding for new projects to address COVID-19

Globally, 350 million could be at risk of severe COVID-19 and hospitalization

Globally, 350 million could be at risk of severe COVID-19 and hospitalization

Study provides genetic explanation behind the sex bias observed in certain diseases

Study provides genetic explanation behind the sex bias observed in certain diseases

Higher prevalence of anxiety disorders in youth with chronic medical conditions

Higher prevalence of anxiety disorders in youth with chronic medical conditions

Rice University wins prestigious grant to develop new therapies for sickle cell disease

Rice University wins prestigious grant to develop new therapies for sickle cell disease

Exploring mechanisms of resistance to HIV in people with sickle cell disease

Exploring mechanisms of resistance to HIV in people with sickle cell disease

Study underscores the need for more precise rare disease definitions

Study underscores the need for more precise rare disease definitions

Certain enzymes implicated in diseases like cancer also destroy each other

Certain enzymes implicated in diseases like cancer also destroy each other

Enzymes that cannibalize each other and promote cancer

Enzymes that cannibalize each other and promote cancer

Effort to control opioids in an ER leaves some sickle cell patients in pain

Effort to control opioids in an ER leaves some sickle cell patients in pain

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

Identifying the type of pain in adults with sickle cell disease may help improve treatment

Identifying the type of pain in adults with sickle cell disease may help improve treatment

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Prenatal screening for hemoglobinopathies different in OBGYN practices and family medicine

Prenatal screening for hemoglobinopathies different in OBGYN practices and family medicine

Pharma’s take on the Pelosi drug-pricing bill: Fair warning or fearmongering?

Pharma’s take on the Pelosi drug-pricing bill: Fair warning or fearmongering?