Sickle Cell Disease

Sickle-cell disease, or sickle-cell anaemia (or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in a risk of various complications.
Understanding Sickle Cell Disease

World Sickle Cell Day is June 19 and was created by the United Nations in 2006 to raise global awareness for sickle cell disease as a public health problem. Sickle cell disease is an extremely debilitating medical condition.

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Overview

Feature Articles

Latest Sickle Cell Disease News and Research

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Health care costs for people with rare diseases have been underestimated, study shows

Health care costs for people with rare diseases have been underestimated, study shows

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Researchers seek to identify the role of hypoxia on red blood cell aging

Researchers seek to identify the role of hypoxia on red blood cell aging

Nemours receives $10.5 million NIH grant to support research in sickle cell disease

Nemours receives $10.5 million NIH grant to support research in sickle cell disease

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

Chief medical officers to consider vaccination of 12 to 15 year olds from a broader perspective

Chief medical officers to consider vaccination of 12 to 15 year olds from a broader perspective

Obstructive sleep apnea may affect heart health and increase blood pressure in children

Obstructive sleep apnea may affect heart health and increase blood pressure in children

Oral prodrug delivers carbon monoxide to protect against acute kidney injury

Oral prodrug delivers carbon monoxide to protect against acute kidney injury

Most states did not use health equity committees to assist with COVID-19 vaccine distribution planning

Most states did not use health equity committees to assist with COVID-19 vaccine distribution planning

Citizens’ jury set to reflect deeply on the pros and cons of human genome editing

Citizens’ jury set to reflect deeply on the pros and cons of human genome editing

Global blood centers join hands to develop more efficient, accurate blood typing technology

Global blood centers join hands to develop more efficient, accurate blood typing technology

UCSF launches new initiative to propel the development of living therapeutics

UCSF launches new initiative to propel the development of living therapeutics

Johns Hopkins researcher receives prestigious award for breakthrough research in circadian science

Johns Hopkins researcher receives prestigious award for breakthrough research in circadian science

Pitt researchers use a unique and powerful MRI device to study sickle cell disease

Pitt researchers use a unique and powerful MRI device to study sickle cell disease

Researchers develop proof-of-concept treatment for blood disorders

Researchers develop proof-of-concept treatment for blood disorders

New technique can help to non-invasively assess progression of sickle cell retinopathy

New technique can help to non-invasively assess progression of sickle cell retinopathy

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

California and Texas took different routes to vaccination. Who’s ahead?

California and Texas took different routes to vaccination. Who’s ahead?

Toward a transformative therapy for sickle cell patients

Toward a transformative therapy for sickle cell patients